An Analysis of Regional Left Ventricular Function Utilizing Pressure-Length Relationship in Patients with Coronary Artery Disease : SYMPOSIUM ON MECHANICS OF CONTRACTION AND RELAXATION OF THE ISCHEMIC MYOCARDIUM : 50th Annual Scientific Session of Japanes
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概要
- 論文の詳細を見る
Mechanisms related to increased left ventricular filling pressure associated with myocardial ischemia were studied in 13 patients with coronary artery disease. Single-plane left ventriculograms were obtained using a high fidelity micromanometer-tipped catheter in the control and post-pacing periods. All patients developed typical anginal pain during pacing tachycardia. Seven patients (group I) demonstrated no significant changes in ejection fraction (EF) and peak systolic pressure-end-systolic volume ratio (P/Ves) after rapid pacing. End-diastolic pressure (EDP), however, increased significantly from 14.9±4.9 to 24.4±8.5 mmHg (p<0.01). The regional myocardial function was expressed by a radial coordinate system with its origin at the center of gravity of the end-diastolic contour. In the normal segment, the end-diastolic length (EDL) was augmented by 13.6%, associated with a 22.4% increase in stroke excursion with pacing stress. In the ischemic segment, EDL remained unchanged, but stroke excursion was significantly reduced. The diastolic pressure-volume curve shifted directly upward or more to the right, while the diastolic pressure-length curve moved up on the single curve in the normal segment and shifted directly upward or more to the right, while the diastolic pressure-length curve moved up on the single curve in the normal segment and shifted directly upward in the ischemic segment, so that pressure was higher at any given segment length in the ischemic segment, indicating regional alteration of the diastolic properties. Thus, an ischemic response to pacing tachycardia Changes in the regional myocardial performance are consistent and the global function is determined by the interaction of changes in regional function of both normal and ischemic myocardium.
- 社団法人日本循環器学会の論文
- 1987-01-20
著者
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Kawai Chuichi
The Kyoto And Shiga Myocardial Infarction (kysmi) Study Group:kyoto University
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MIYAZAKI SHUNICHI
The Third Division, Department of Internal Medicine, Kyoto University Hospital
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Miyazaki Shunichi
The Third Division Department Of Internal Medicine Kyoto University Hospital
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Kawai Chuichi
The Third Division Department Of Internal Medicine. Faculty Of Medicine Kyoto University
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Kawai Chuichi
The Third Division Department Of Internal Medicine Kyoto University And Department Of Medicine Beth
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Sasayama Shigetake
The Third Division Of Medicine Kyoto University
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NONOGIH HIROSHI
Otowa Hospital, Kyoto
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SASAYAMA SHIGETAKE
TheSecond Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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Sawada Shigeo
Virus Center National Kyoto Hospital
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Sasayama Shigetake
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Sasayama Shigetake
Division Of Medicine Hamamatsu Rosai Hospital Shizuoka
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Kawai Chuichi
The Third Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Kawai Chuichi
3rd Div. Dept Of Intern Med. Kyoto Univ
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Miyazaki Shunichi
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Sasayama Shigetake
Department Of Cardiology Doshisha University
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Sasayama Shigetake
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Miyazaki Shunichi
The Third Division Department Of Internal Medicine Kyoto University
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Nonogih Hiroshi
Otowa Hospital Kyoto
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Sasayama Shigetake
Third Division Department Of Internal Medicine Kyoto University
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Sasayama Shigetake
Second Division Internal Medicine Toyama Medical And Pharmaceutical School
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Sasayama Shigetake
Thesecond Department Of Internal Medicine Toyama Medical And Pharmaceutical University
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