Experimental Coxsackievirus B3 Perimyocarditis in the Right Ventricle in BALB/c Mice: a One-year Follow-up Study : Proceedings of the IV Conference on Prevention for Rheumatic Fever and Rheumatic Heart Disease, January 1979, Kyoto
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概要
- 論文の詳細を見る
We described severe perimyocarditis in weanling BALB/C mice inoculated with coxsackievirus B3 (Nancy strain) which was exclusively limited to the right ventricle. Yellowish-white patches were seen on the surface of the right ventricle of the heart on the seventh day through 360th day after inoculation with virus. Following myocardial degeneration and necrosis, marked perimyocardial fibrosis with calcification was observed 90 days after inoculation with virus and persisted through 360th day. Spontaneous pericardial lesions were observed in the right ventricle in a few control mice, but these changes were different in severity and localization from perimyocarditis observed in mice infected with coxsackievirus B3. This animal model may provide an opportunity to study the natural course of perimyocarditis of viral etiology and possible sequel chronic or constrictive pericarditis in humans."
- 社団法人日本循環器学会の論文
- 1980-11-20
著者
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Kawai Chuichi
The 3rd Division Dept. Of Intern. Med. Kyoto University School Of Medicine And Osaka Medical College
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Sasayama Shigetake
浜松労災病院
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MATSUMORI AKIRA
The 3rd Division, Department of International Medicine, Faculty of Medicine
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Sawada Shigeo
Department Of Cardiology Doshisha University
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Sasayama Shigetake
The Third Division Of Medicine Kyoto University
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SAWADA SHIGEO
Virus Center, National Kyoto Hospital
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Sawada Shigeo
Virus Center National Kyoto Hospital
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Sasayama Shigetake
Division Of Medicine Hamamatsu Rosai Hospital Shizuoka
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Kawai Chuichi
The 3rd Department Of Internal Medicine Kyoto University School Of Medicine
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Sasayama Shigetake
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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YAMAMOTO KIYOHARU
Virus Center, National Kyoto Hospital
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Matsumori Akira
The 3rd Department Of Medicine. Faculty Of Medicine Kyoto University
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Yamamoto Kiyoharu
Virus Center National Kyoto Hospital
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Sasayama Shigetake
Thesecond Department Of Internal Medicine Toyama Medical And Pharmaceutical University
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Sawada Shigeo
Division Of Medicine Hamamatsu Rosai Hospital Shizuoka
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