ROLE OF MESANGIAL PROLIFERATION IN ANGIOTENSIN II AND ANTIDIURETIC HORMONE INDUCED CHANGES IN GLOMERULAR FILTRATION RATE

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概要

• 論文の詳細を見る

• The effects of administration of angiotensin II (ANG II) and antidiuretic hormone (ADH) on the glomerular filtration rate (GFR, measured as creatinine clearance) were examined in patients with mesangial proliferation. For this study, the patients whose conditions were similar to that of healthy subjects, except for asymptomatic urinary abnormalities and glomerular histological changes, were selected. Both ANG II and ADH administration significantly decreased GFR in the patients and the healthy subjects. Compared to the healthy subjects, a significantly greater drop in GFR was observed in the patients following ANG II infusion with or without SQ14225 administration, but not following ADH infusion. We conclude that mesangial proliferation may modulate an ANG II induced drop in GFR.

• 社団法人日本循環器学会の論文
• 1985-11-20

著者

• Fujiwara Yoshihiro

  Department Of Medicine Osaka University Medical School

• ORITA Yoshimasa

  Department of Clinical Laboratory Science, School of Allied Health Sciences, Faculty of Medicine Osa

• Takamitsu Yoshihiro

  Department Of Medicine Kagawa Medical School

• Abe Hiroshi

  Cardiovascular Division Osaka National Hospital

• SASAKI Eiki

  Department of Medicine, Osaka University Medical School

• MIKI Shigehiro

  Medicine, Kagawa Medical School

• ABE Hiroshi

  Osaka National Hospital

• Yamabe Takashi

  National Cardiovascular Center

• Sasaki Eiki

  Department Of Medicine Osaka University Medical School

• Miki Shigehiro

  Medicine Kagawa Medical School

• Fujiwara Yoshihiro

  Department Of Anesthesiology Aichi Medical University

• Orita Yoshimasa

  Department Of Medicine Osaka University Medical School

• Orita Y

  First Department Of Internal Medicine:osaka University Hospital

• Orita Yoshimasa

  Department Of Clinical Laboratory Science School Of Medicine Osaka University

• Takamitsu Yoshihiro

  The First Department Of Medicine Osaka University Medical School

• Takamitsu Yoshihiro

  Department Of Medicine Hospital And Research Institute National Cardiovascular Center

• Orita Yoshimasa

  The First Department Of Medicine Osaka University Medical School

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