Influence of Peripheral Vascular Occlusive Disease on the Morbidity and Mortality of Coronary Artery Bypass Grafting
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概要
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The impact of peripheral vascular occlusive disease(PVD) on outcome for patients who have undergone coronary artery bypass grafting(CABG) was assessed by comparing preoperative and intraoperative patient characteristics and outcome in 2 groups of patients who underwent CABG (patients with PVD, n=96; patients without PVD, n=593). Patients with PVD were significantly older (69±8.4 vs 63±8.7; p<0.0001), and had a higher incidence of diabetes mellitus (48% vs 32%; p<0.01), hypertension (62% vs 46%; p<0.01), preoperative cerebral infarction (26% vs 12%; p<0.001) and chronic renal dysfunction (11% vs 4.4%; p<0.01) than those without PVD. Postoperative morbidity and mortality were assessed, after those risk factors were adjusted, using multivariate logistic regression analysis. The perioperative myocardial infarction(PMI) rate and in-hospital mortality rate were significantly higher in patients with PVD than in patients without PVD (9.4% vs 3.0%; p=0.0108, 17% vs 2.7%; p=0.0003, respectively). The odds ratio of PMI and in-hospital mortality were 3.4 (95% confidence intervals (CI): 1.3-8.6) and 4.3 (95% CI: 2.0-9.5), respectively. Although the excess mortality rate was mainly the result of cardiac problems, such as low output syndrome or arrhythmia, in most of the cases, PVD, which may frequently prevent the use of the intraaortic balloon pump, also seemed to have a strong relation to postoperative morbidity and mortality.
- 社団法人日本循環器学会の論文
- 2000-11-20
著者
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MATSUMOTO Masahiko
Department of Biochemistry, School of Medicine, Tokai University
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KONISHI YUTAKA
Department of Cardiovascular Surgery
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Sugimoto Akihiro
Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University
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Aota Masaki
Department of Cardiovascular Surgery Kyoto University Faculty of Medicine
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Aota Masaki
Department Of Cardiovascular Surgery Japanese Red Cross Society Wakayama Medical Center
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Matsumoto Masahiko
Department Of Biochemistry School Of Medicine Tokai University
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Konoshi Yutaka
Department Of Cardiovascular Surgery Japanese Red Cross Society Wakayama Medical Center
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Matsumoto Masahiko
Department Of Cardiovascular Surgery Japanese Red-cross Sociaty Wakayama Medical Center
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Minakata Kenji
Department of Cardiovascular Surgery, Japanese Red Cross Society Wakayama Medical Center
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Nonaka Michihito
Department of Cardiovascular Surgery, Japanese Red Cross Society Wakayama Medical Center
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Yamada Narihisa
Department of Cardiovascular Surgery, Japanese Red Cross Society Wakayama Medical Center
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Minakata Kenji
Department Of Cardiovascular Surgery Japanese Red-cross Sociaty Wakayama Medical Center
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Sugimoto Akihiro
Department Of Cardiovascular Surgery Japanese Red Cross Society Wakayama Medical Center
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Yamada Narihisa
Department Of Cardiovascular Surgery Japanese Red-cross Sociaty Wakayama Medical Center
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Minakata Kenji
Department Of Cardiovascular Surgery Japanese Red Cross Society Wakayama Medical Center
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Konishi Yutaka
Department Of Cardiovascular Surgery Japanese Red-cross Sociaty Wakayama Medical Center
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Nonaka Michihito
Department Of Cardiovascular Surgery Japanese Red Cross Society Wakayama Medical Center
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