Stress-Induced ST-Segment Elevation Following Myocardial Infarction and Its Role in Wall Motion Abnormality, Myocardial Ischemia and Viability : Comparison of Response to Exercise, Dobutamine and Dipyridamole
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概要
- 論文の詳細を見る
Stress-induced ST-segment elevation following myocardial infarction(MI)has been correlated with myocardial ischemia, viability and wall motion abnormality, but its mechanism is still unclear, so the present study compared ST-segment elevation and wall motion response during exercise, dobutamine and dipyridamole stresses. Twentyfive, patients with their first anterior MI underwent exercise, dobutamine and dipyridamole echocardiography on different days 4-6 weeks after MI. Left ventricular wall motion was analyzed using 5-grade/16-segment model and myocardial ischemia was considered as a worsening of the wall motion score index(WMSI)during the stress test; myocardial viability was defined as a reduction of WMSI during low dose dobutamine. Dyskinesis formation was defined by visual analysis as akinesis that became dyskinetic or if the dyskinesis worsened. Both exercise and dobutamine induced ST-segment elevation, but dipyridamole did not. There was no significant difference in the degree of ST-segment elevation between the patients with and without myocardial ischemia or dyskinesis formation. Exercise induced a higher ST-segment elevation in patients with myocardial viability than those without(0.17±0.09 mV vs 0.09±0.07 mV, p<0.05). Exercise-induced ST-segment elevations correlated with dobutamineinduced ST-segment elevations(p<0.01), changes in heart rate(p<0.05)and systolic blood pressure(p<0.05). In conclusions, stress-induced ST-segment elevation does not correlate with either myocardial ischemia or stressinduced dyskinesis, but may be associated with myocardial viability.
- 社団法人日本循環器学会の論文
- 2001-11-20
著者
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Yamamoto Toshio
Life Science Institute Kinki University School Of Medicine
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MIYAZAKI Toshio
First Department of Internal Medicine, Kinki University School of Medicine
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YAMAMOTO Tadahiko
First Department of Internal Medicine, Kinki University School of Medicine
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Hirano Yutaka
First Department of Internal Medicine, Kinki University School of Medicine
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Miyazaki Toshio
The First Department Of Medicine Kinki University School Of Medicine
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Miyazaki Toshio
First Department Of Internal Medicine Kinki University School Of Medicine
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Yamamoto Toshio
First Department Of Internal Medicine Kinki University School Of Medicine
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Tashi Masahiro
First Department Of Internal Medicine Kinki University School Of Medicine
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Hirano Yutaka
Division Of Clinical Laboratory Kinki University Hospital
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Tashi Masahiro
The First Department Of Medicine Kinki University School Of Medicine
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lshikawa Kinji
First Department of Internal Medicine, Kinki University School of Medicine
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Yamamoto Tadahiko
First Department Of Internal Medicine Kinki University School Of Medicine
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Yamamoto Tadahiko
The First Department Of Medicine Kinki University School Of Medicine
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Hirano Yutaka
First Department Of Internal Medicine Kinki University School Of Medicine
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Lshikawa Kinji
First Department Of Internal Medicine Kinki University School Of Medicine
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