Subacute and Chronic Effects of DDD Pacing on Left Ventricular Diastolic Function in Ptients With Non-Obstructive Hypertrophic Cardiomyopathy
スポンサーリンク
概要
- 論文の詳細を見る
The present study examined the ability of dual-chamber (DDD) pacing to improve symptoms and exercise tolerance in patients with non-obstructive hypertrophic cardiomyopathy (HNCM). Seven patients with HNCM who had failed to benefit from pharmacotherapy participated in the study. The New York Heart Association (NHYA) functional class status and execise tolerance, which was determined by the treadmill exercise test, were recorded and an echocardiographic observation was performed before, and 1 week, 3 months and 1 year after the implantation of a permanent DDD pacemaker. The atrioventricular delay (AVd) was determined by measuring the point of peak rapid filling velocity and maximum cardiac output (CO). Two patients were not implanted with a permanent pacemaker because their CO and blood pressure decreased or because palpitation occurred during temporary pacing. The ratio between early and late peaks of flow velocity (1.56, 1.21, 0.95, and 0.86 before implantation and 1 week, 3 months and 1 year after implantation, respectively; deceleration time (ms: 263.2, 217.6, 204.6, 187.0); peak filling rate (m1/s: 146.2, 204.0, 233.2, 243.6); NYHA functional class status (2.0, 1.8, 1.6, 1.4); and exercise tolerance (s: 203, 264, 403, 480) were significantly improved after implantation. However, left ventricular dimension, percent fractional shortening, ejection fraction, acceleration time and the isovolumic relaxation time were not changed significantly. In conclusion, DDD pacing improved symptoms and the NYHA functional class status, which is associated with improvement of left ventricular diastolic function. It is proposed that DDD pacing would be useful in patients not only with obstructive but also non-obstructive hypertrophic cardiomyopathy refractory to medical treatment, depending on the careful selection of subjects.
- 社団法人日本循環器学会の論文
- 2001-03-20
著者
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SUZUKI Jun
Department of Health Care Chemistry, College of Environmental Health, Azabu University
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Watanabe Kouki
Uwashima City Hospital
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Watanabe Kouki
Department Of Biofunctional Science Faculty Of Agriculture And Life Science Hirosaki University
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SUEDA Shozo
Department of Internal Medicine, Ehime Prefectural Niihama Hospital
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Funada Jun-ichi
Department of Cardiology, Ehime National Hospital
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Sekiya Michihito
Department of Cardiology, Ehime National Hospital
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Watanabe Koki
Uwashima City Hospital
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Ikeda Shuntaroh
Department of Internal Medicine, Ehime Prefectural Minamiuwa Hospital
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Tsuruoka Takashi
Department of Internal Medicine, Ehime Prefectural Minamiuwa Hospital
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Funada Jun-ichi
Department Of Cardiology Ehime National Hospital
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Sueda Shozo
Department Of Cardiology Saiseikai Saijo Hospital
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Sueda Shozo
Department Of Cardiology Ehime Prefectural Niihama Hospital
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Suzuki Jun
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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Funada Jun-ichi
Department Of Cardiology Saiseikai Saijo Hospital
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Sekiya Michihito
Department Of Cardiology Ehime Hospital
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Sekiya Michihito
Department Of Cardiology Ehime Natinal Hospital
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Watanabe Koki
Saiseikai Matsuyama Hospital
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Tsuruoka Takashi
Department Of Internal Medicine Ehime Prefectural Minamiuwa Hospital
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Watanabe Kouki
Department Of Cardiology Uwajima City Hospital
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Funada Junnichi
Department Of Cardiology Ehime National Hospital
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Sekiya Michihito
Department Of Cardiology Saiseikai Saijo Hospital
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Ikeda Shuntaroh
Department Of Internal Medicine Ehime Prefectural Minamiuwa Hospital
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Suzuki Jun
Department Of Cardiology Saiseikai Saijo Hospital
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Watanabe Kouki
Department Of Cardiology Saiseikai Saijo Hospital
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Tsuruoka Takashi
Department of Cardiology, Kita Medical Association Hospital
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