Influence of Aerobic Exercise Training on Brain Natriuretic Peptide Secretion in Patients in the Chronic Phase of Myocardial Infarction
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概要
- 論文の詳細を見る
Brain natriuretic peptide(BNP)secretion increases after myocardial infarction(MI);its plasma level may reflect the degree of left ventricular dysfunction.This study examines how aerobic exercise therapy for MI influences BNP secretion.Subjects included 70 patients(mean age, 62.0±11.3 years)who were divided into four groups:(1)20 patients with an anterior MI and exercise training;(2)20 patients with an anterior MI and no exercise training;(3)15 patients with an inferior MI and exercise training;and(4)15 patients with an inferior MI and no exercise training.The training groups performed aerobic exercise 3 times a week for 2 months.Exercise intensity was defined as a heart rate of anaerobic threshold(AT), derived from the treadmill cardiopulmonary exercise testing at 1 month after the onset of MI.The subjects underwent cardiopulmonary exercise testing again at 3 months after the onset of MI.To measure BNP, blood samples were obtained in the resting state and immediately after the peak exercise.AT and peak oxygen uptake increased in the training group with anterior MI and in both the training and nontraining groups with inferior MI.Significant serial change in plasma BNP level was not observed in the inferior MI groups.Plasma BNP level decreased longitudinally only in the nontraining anterior MI group.It was concluded that exercise training in patients with an anterior MI could delay the recovery of left ventricular function, but will increase exercise tolerance.
- 社団法人日本循環器学会の論文
- 1998-08-20
著者
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Itoh Haruki
Second Department of Internal Medicine, Tokyo Medical And Dental University
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Itoh Haruki
Second Department Of Internal Medicine Akita University
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Murayama Masahiro
Division Of Cardiology St. Marianna University School Of Medicine
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Iinuma Hiroyuki
鹿児島大学 大学院医歯学総合研究科循環器･呼吸器･代謝内科学
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Kawara Tokuhiro
心臓血管研究所
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Yamamoto Akiko
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Yokoyama Yasuhiro
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Tanabe Kazuhiko
Second Department of Internal Medicine, St Marianna University School of Medicine
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Yamamoto Akiko
Second Department of Internal Medicine, St Marianna University School of Medicine
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Yokoyama Yasuhiro
Second Department of Internal Medicine, St Marianna University School of Medicine
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Murayama Masahiro
Second Department of Internal Medicine, St Marianna University School of Medicine
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Yokoyama Yasuhiro
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Tanabe Kazuhiko
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Yamamoto Akiko
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Murayama Masahiro
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Yamamura Yukio
The Department Of Public Health St. Marianna University School Of Medicine
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Yamuura Yukio
Department Of Public Health St. Marianna University School Of Medicine
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Murayama Masahiro
The Second Department Of Internal Medicine St. Marianna University School Of Medecine
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Murayama Masahiro
Department Of Internal Medicine (cardiology) St Marianna University
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Murayama Masahiro
Second Department Of Internal Medicine St Marianna University School Of Medicine
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Murayama Masahior
The 2nd Department Of Internal Medicine St. Marianna University
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Murayama Masahiro
The Second Department Of Internal Medicine St Marianna University School Of Medicine
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