Magnesium Dynamics and Relation to Left Ventricular Function in Acute Myocardial Infarction
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概要
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The present study investigated the serial changes in serum magnesium (Mg) and erythrocyte concentration of Mg in patients with acute myocardial infarction (AMI) and the relationship between these changes and left ventricular ejection fraction (LVEF) at 1 month after the onset of infarction. The study group comprised 26 patients with AMI (mean age, 57.9±8.9 years). Serum Mg and erythrocyte Mg were measured on hospital days 1, 2, 4, 7 and 21. The change in erythrocyte Mg during the acute phase was calculated as a ratio: [(erythrocyte Mg at day 2)-(erythrocyte Mg at day 1)]/(erythrocuyte Mg at day 1). The change in serum Mg was calculated similarly. The following results were obtained. (1) Serum Mg tended to increase from the onset of myocardial infarction (day 1: 1.86±0.19, day 2: 1.93±0.22, day 4: 2.17±0.23, day 7: 2.25±0.20; day 21: 2.12±0.15 mg/dl). (2) Erythrocyte Md on day 2 and day 4 showed a significalt decrease compared with day 1 (day 1: 2.45±0.40, day 2: 2.09±0.41, day 4: 2.07±0.37, day 7: 2.22±0.33, day 7: 2.34±0.28 mg/dl per 400×10^4/mm^3 cells).(3) A significant positive correlation was observed between the change in serum Mg and LVEF (r=0.55, p<0.05), and a significant negative correlation was observed between the change in erythrocyte Mg and LVEF (r=-0.57, p<0.05). Thus, it was concluded that an extracellular shift in intracellular Mg occurred during the first 2 days after the onset of myocardial infarction. This responsive increase in the extracellular Mg level may be an important factor for maintaining left ventricular function in patients 1 month after the onset of AMI.
- 社団法人日本循環器学会の論文
- 2000-04-20
著者
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Suzuki Noriyuki
Division Of Cardiology St. Marianna University School Of Medicine
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Itoh Haruki
Department Of Cardiology Sakakibara Heart Institute
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Itoh Haruki
心臓血管研究所
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Tanabe Kazuhiko
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Murayama Masahiro
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Murayama Masahiro
Division Of Cardiology St. Marianna University School Of Medicine
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Nakayama Masaru
Third Department Of Internal Medicine Showa University School Of Medicine
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Osada Naohiko
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Osada Naohiko
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Iinuma Hiroyuki
鹿児島大学 大学院医歯学総合研究科循環器･呼吸器･代謝内科学
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OMIYA Kazuto
Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine
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MIYAKE Fumihiko
Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine
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Kawara Tokuhiro
心臓血管研究所
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Nakayama Masaru
Division Of Cardiology The Cardiovascular Institute
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Itoh Haruki
Division of Cardiology, The Cardiovascular Institute
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Yamamoto Akiko
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Yokoyama Yasuhiro
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Oya Misa
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Murabayashi Taizo
Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine
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Yokoyama Yasuhiro
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Omiya Kazuto
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Nakayama Masaru
Department Of Cardiology Sakakibara Heart Institute
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Miyake Fumihiko
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Tanabe Kazuhiko
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Oya Misa
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Itoh Haruki
Division Of Cardiology The Cardiovascular Institute
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Yamamoto Akiko
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Murabayashi Taizo
Division Of Cardiology Department Of Internal Medicine St. Marianna University School Of Medicine
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Nakayama Masaru
Division Of Cardiology Kashima Hospital
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Oya Misa
The Cardiovascular Institute
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Murayama Masahiro
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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Yamamura Yukio
The Department Of Public Health St. Marianna University School Of Medicine
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Yamuura Yukio
Department Of Public Health St. Marianna University School Of Medicine
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Murayama Masahiro
The Second Department Of Internal Medicine St. Marianna University School Of Medecine
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Murayama Masahiro
Department Of Internal Medicine (cardiology) St Marianna University
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Murayama Masahior
The 2nd Department Of Internal Medicine St. Marianna University
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Murayama Masahiro
The Second Department Of Internal Medicine St Marianna University School Of Medicine
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Miyake Fumihiko
Division Of Cardiology Department Of Internal Medicine St Marianna University School Of Medicine
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