Granulocyte Activation in Restenosis After Percutaneous Transluminal Coronary Angioplasty
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概要
- 論文の詳細を見る
To examine whether or not granulocyte activation is involved in restenosis after percutaneous transluminal coronary angioplasty (PTCA), we prospectively followed the time course of the plasma level of granulocyte elastase, which is an index of granulocyte activation, before and after successful angioplasty in 43 consecutive patients. Restenosis was defined as a more than 50% loss of the initial gain in the coronary diameter achieved by PTCA with more than a 50% resultant stenosis in the follow-up coronary arteriography performed 3 months after PTCA. There was no difference in the level of granulocyte elastase between the 2 groups with (n=15) and without (n=28) restenosis before, the day after and 1 month after PTCA. However, 3 months after PTCA, the level of granulocyte elastase was significantly higher in the group with restenosis than in that without restenosis (171±13 vs 147±6 mg/l, P<0.05). The level of granulocyte elastase at 3 months after PTCA also correlated significantly with the percent luminal stenosis at the angioplasty site (P<0.05). These results suggest that granulocyte activation may be involved in restenosis after PTCA.
- 社団法人日本循環器学会の論文
- 1995-12-20
著者
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Tsutsui Masato
Department Of Pharmacology School Of Medicine University Of Occupational And Environmental Health
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Shimokawa Hiroaki
Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit
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Shimokawa Hiroaki
Research Institute Of Angiocardiology And Cardiovascular Clinic Kyushu University School Of Medicine
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Matsuguchi Takeyuki
The Department Of Cardiology Iizuka Hospital
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Okamatsu Shuichi
Department Of Cardiology Aso-iizuka Hospital
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Okamatsu Shuichi
The Department Of Cardiology Iizuka Hospital
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Tanaka Seiya
Department of Cardiology and Nephrology, University of Occupational & Environmental Health
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Higuchi Seiji
The Department of Cardiology, Iizuka Hospital
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YOSHIHARA Shingo
Department of Chemistry and Material Engineering, Shinshu University
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Tanaka Seiya
Department Of Cardiology And Nephrology University Of Occupational & Environmental Health
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Tanaka Seiya
Department Of Cardiology Iizuka Hospital
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Higuchi Seiji
The Department Of Cardiology Iizuka Hospital
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Tsutsui Masato
Department Of Dermatology Asahikawa Medical College
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Tsutsui Masato
The Department Of Cardiology Iizuka Hospital
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Higuchi Seiji
Department of Cardiology, Iizuka Hospital
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Matsuguchi Takeyuki
Department of Cardiology, Iizuka Hospital
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Yoshihara Shingo
The Department Of Cardiology Iizuka Hospital
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Yoshihara Shingo
Department Of Chemistry And Material Engineering Shinshu University
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TSUTSUI Masato
Department of Cardiology, Iizuka Hospital
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