Intracellular Magnesium Deficiency in Acute Myocardial Infarction.
スポンサーリンク
概要
- 論文の詳細を見る
It has been hypothesized that intracellular magnesium deficiency is a pathogenetic factor in acute myocardial infarction. This study examined the time course of changes in the erythrocyte magnesium concentration and the correlation between the erythrocyte magnesium concentration and the severity of acute myocardial infarction in 49 consecutive patients with transmural acute myocardial infarction. The data were compared with results from 20 control patients without ischemic heart disease. The erythrocyte magnesium concentration (mg/dl) decreased significantly during the acute phase of the infarction (4.86±0.09 on day 1, 4.89±0.10 on day 2 and 4.86±0.10 on day 3 versus 5.26±0.19 for controls, all P<0.05) and then normalized gradually to 5.25±0.10 on day 28. The serum magnesium concentration (mg/dl) also decreased significantly during the acute phase of the infarction (1.93±0.04 on day 1 and 2.11±0.03 on day 2 versus 2.26±0.08 for controls, all P<0.05), before recovering to 2.28±0.06 on day 28. There were significant correlations between the erythrocyte magnesium concentration on day 1 and maximal values of serum cardiac enzymes (r=-0.30 for creatine kinase, r=-0.34 for glutamic oxaloacetie transaminase and r=-0.57 for lactate dehydrogenase, all P<0.05). Moreover, the erythrocyte magnesium concentration was significantly lower in patients with (4.32±0.08mg/dl, n=13) than in those without (5.06±0.09mg/dl, n=36, P<0.0001) serious arrhythmias. These data indicate that intracellular magnesium deficiency is involved in the acute phase of myocardial infarction.
- International Heart Journal刊行会の論文
著者
-
Okamatsu Shuichi
Department Of Cardiology Aso-iizuka Hospital
-
Sobashima Atsushi
Department Of Cardiovascular Medicine Aso-iizuka Hospital
-
Hayashida Kiyoshi
Department Of Astrophysics Osaka University
-
Shimokawa Hiroaki
Department Of Cardiology Tohoku University School Of Medicine
-
Higuchi Seiji
Department of Cardiology, Iizuka Hospital
-
Matsuguchi Takeyuki
Department of Cardiology, Iizuka Hospital
-
Yoshihara Shingo
Department Of Chemistry And Material Engineering Shinshu University
-
Yamamoto Kunihiko
Department Of Anesthesiology And Critical Care Medicine Asahikawa Medical College
-
TSUTSUI Masato
Department of Cardiology, Iizuka Hospital
-
YAMAMOTO Kunihiko
Department of Cardiology, Iizuka Hospital
-
SHIMOKAWA Hiroaki
Department of Cardiology, Iizuka Hospital
-
YOSHIHARA Shingo
Department of Cardiology, Iizuka Hospital
-
SOBASHIMA Atsushi
Department of Cardiology, Iizuka Hospital
関連論文
- Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris
- PJ-302 High-Resolution Measurement of Carotid Artery Wall Elasticity for Clinical Tailor-Made Risk Management of Arteriosclerosis(Atherosclerosis, clinical-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Suzaku Observations of Abell 1795 : Cluster Emission to r_
- Long-Term Treatment with Eicosapentaenoic Acid Improves Exercise-Induced Vasodilation in Patients with Coronary Artery Disease
- New CTI Correction Method for Spaced-Row Charge Injection of the Suzaku X-Ray Imaging Spectrometer
- Energy-Scale Calibration of the Suzaku X-Ray Imaging Spectrometer Using the Checker Flag Charge-Injection Technique in Orbit
- Reproducibility of Non-X-Ray Background for the X-Ray Imaging Spectrometer aboard Suzaku
- The X-Ray Observatory Suzaku
- Guidelines for Diagnosis and Treatment of Patients With Vasospastic Angina (Coronary Spastic Angina) (JCS 2008) : Digest Version
- Trends in Acute Myocardial Infarction Incidence and Mortality Over 30 Years in Japan : Report From the MIYAGI-AMI Registry Study
- Evidence for Rho-Kinase Activation in Patients With Pulmonary Arterial Hypertension
- PJ-477 Diagnostic Usefulness of Vasodilator Test with Inhaled Nitric Oxide in Patients with Pulmonary Veno-Occlusive Disease(PJ080,Pulmonary Circulation 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PE-445 Renin-Angiotensin System Plays an Important Role in Diabetes Mellitus-Induced Diastolic Dysfunction in Hypertensive Rats(PE075,Heart Failure (Pathophysiology) (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulati
- PE-444 Prognostic Impact of Myocardial Fibrosis in Systolic Heart Failure : New Aspect of Usefulness of Myocardial Biopsy(PE075,Heart Failure (Pathophysiology) (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Soc
- PE-349 Gender Difference in the Responsiveness to Corticosteroid Therapy in Patients with Cardiac Sarcoidosis(PE059,Heart Failure (Treatment) 2 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-129 Genetic Deletion of OX40 Ligand Suppresses the Development of Atherosclerosis in Apolipoprotein E-Deficient Mice(PE022,Atherosclerosis, Basic (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Optical Coherence Tomography as a Novel Diagnostic Tool for Distal Type Chronic Thromboembolic Pulmonary Hypertension
- X-Ray Properties of the Nucleus of M81
- 1 Current Status of Vasospastic Angina in Japan : An Interim-report of the Multicenter Registry of the Coronary Spasm Association of Japan(Recent Progress in the Management of Vasospastic Angina,Meet the Expert 6 (ME-6) (IHD),The 73rd Annual Scientific Me
- 2 Microvascular Angina : Invisible but Important Player in Cardiovascular Gender Medicine(Recent Progress of Gender-specific Medicine in Cardiology,Meet the Expert 4 (ME-4) (H),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Lamin A/C Gene Mutations in Familial Cardiomyopathy with Advanced Atrioventricular Block and Arrhythmia
- Importance of Dual Induction Tests for Coronary Vasospasm and Ventricular Fibrillation in Patients Surviving Out-of-Hospital Cardiac Arrest
- 1 Importance of Medical Treatment for Vasospastic Angina : Lessons from Multicenter Registry by Coronary Spasm Association of Japan(Therapeutic Decision Making for Coronary Artery Disease Among PCI, CABG, and Medication,Symposium 3 (SY-03) (IHD),The 73rd
- Electrophysiological Properties of the Right Atrial Septum in Patients with Atrial Tachyarrhythmias
- OJ-261 Hydrogen Peroxide Derived from Beating Heart Mediates Coronary Microvascular Dilatation during Tachycardia in Dogs in Vivo(Coronary circulation, basic/clinical-2 (IHD) OJ44,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting
- OE-218 Risk Factors and Incidence of Pulmonary Embolism in Japan 2004(Thromboembolism/Antithrombotic therapy/Thrombolysis-1 (H) OE37,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Diabetes mellitus accelerates left ventricular diastolic dysfunction through activation of the renin-angiotensin system in hypertensive rats
- PJ-171 Pravastatin Ameliorates Hypoxia-Induced Pulmonary Arterial Hypertension Through Down-regulation of Stromal Cell-Derived Factor-1 in Mice(Pulmonary circulation(03)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circul
- Prognostic Importance of Chronic Kidney Disease in Japanese Patients With Chronic Heart Failure : Implications of the CHART Study
- PE-483 Prognostic Impact of Central Sleep Apnea in Patients with Chronic Heart Failure(Heart failure, clinical-9 (M) PE81,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-385 End-tidal Carbon Dioxide Predicts the Responsiveness of Patients with Chronic Heart Failure Associated with Central Sleep Apnea to Oxygen Therapy(Heart failure, clinical-6 (M) OJ65,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific
- OJ-247 Chronic Hypoxia Mobilizes Smooth Muscle Progenitors in Mice(Vascular smooth muscles-1 (H) OJ42,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-103 Therapeutic Importance of Angiotensin-Converting Enzyme Inhibitor and/or Angiotensin Receptor Blocker in Patients with Diastolic Heart Failure(Heart failure, clinical-4 (M) OJ18,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Me
- OE-168 Hemoglobin Level Predicts Sudden Death in Patients with Diastolic Heart Failure(Heart failure, clinical-1 (M) OE28,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 1 Accumulated Risks and Non-Optimum Medical Treatment in Japanese Older Patients with Chronic Heart Failure : Results from the CHART Study(Characteristics and Management Strategies of Chronic Heart Failure in the Japanese,Symposium 12 (SY12) (M),The 70th
- PE-171 Co-existence of Coronary Vasospasm and Ventricular Fibrillation in Patients Survived from Out-of-Hospital Cardiac Arrest(PE029,Cardiopulmonary and Critical Care/ACLS (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Ci
- PE-004 Significance of Basal Coronary Artery Tone in Patients with Vasospastic Angina : Analysis by Using Quantitative Coronary Angiography(Angina pectoris, basic/clinical(03)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese
- OE-393 Importance of Dual Induction Test for Coronary Vasospasm and Ventricular Fibrillation in Patients Survived from Out-of-Hospital Cardiac Arrest(Emergency care/CPR(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese C
- PJ-759 Equivalent Inhibitory Effects of 4.0-mm-Diameter Bare Metal Stent with 3.5-mm-Diameter Drug-eluting Stent to Prevent Restenosis after Percutaneous Coronary Intervention(Coronary revascularization, PCI-22, The 71st Annual Scientific Meeting of the J
- PJ-329 Low-dose of Thyroid Hormone Restores Depressed Contractility and Impaired Calcium Handling in Chronically Unloaded Heart in Rats(Cardiac function, basic/clinical-4 (M) PJ56,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of
- Slim-Disk model for Soft X-Ray Excess and Variability of Narrow-Line Seyfert 1 Galaxies
- Extracorporeal Shock Wave Therapy as a New and Non-invasive Angiogenic Strategy
- PJ-731 Genetic Disruption of All Nitric Oxide Synthase Isoforms Causes Accelerated Renal Lesion Formation in Mice in Vivo(PJ123,Kidney/Renal Circulation/CKD 6 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Soc
- PJ-693 Inhibition of Sodium Channels Enhances Arrhythmogenic Regional Endocardial Substrate in Patients with Brugada Syndrome(PJ116,Ventricular Arrhythmia (Clinical/Pathophysiology) (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The J
- PJ-533 Role of H_2O_2 as an Endogenous EDHF during Coronary Occlusion and Injection of Erythropoietin in Canine Coronary Native Collateral Microvessels(PJ090,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Poster Session (Japanese),Th
- PJ-234 Usefulness of Cardiac Magnetic Resonance Imaging to Evaluate Cardiac Dyssynchrony in Patients with Chronic Heart Failure(PJ040,CRT/ICD 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-188 Combination Therapy with an Angiotensin Receptor Blocker and a Calcium Channel Blocker Improves EDHF-Mediated Responses in Diabetic Apolipoprotein E-Deficient Mice(PJ032,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 1 (H),Poster
- PE-451 Extracorporeal Cardiac Shock Wave Therapy Ameliorates Left Ventricular Remodeling after Myocardial Ischemia-Reperfusion Injury in Pigs in Vivo(PE076,Regeneration (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circul
- OJ-046 Evidence for Rho-kinase Activation in Patients with Pulmonary Arterial Hypertension(OJ08,Pulmonary Circulation (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- 3 Evidence for Rho-kinase Activation in Patients with Pulmonary Arterial Hypertension(Young Investigator's Award for International Students Finalists Lecture (YIA International),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- 5 Differential Roles of Progenitor Cells in the Arterial Development of the Abnormal Vasculature(Young Investigator's Award Finalists Lectures (YIA),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Performance of the Charge-Injection Capability of Suzaku XIS
- Orbital Calibration of the XIS(Chapter 12. Instructions of Suzaku Data Analysis, The Extreme Universe in the Suzaku Era)
- Suzaku Observations of Abell 1795 : Cluster Emission to r_(Chapter 2. Thermal Structure/Dynamics of Groups and Clusters of Galaxies, The Extreme Universe in the Suzaku Era)
- Search for Oxygen Emission from Warm-Hot Intergalactic Medium around A 2218 with Suzaku
- X-Ray Imaging Spectrometer (XIS) on Board Suzaku
- OE-298 Cyclophilin A Promotes Vascular Oxidative Stress and Accelerates Development of Angiotensin II-induced Aortic Aneurysms(OE51,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) (H),Oral Presentation (English),The 73rd Annual Scientific
- OE-234 Cyclophilin A is a Novel Pro-Inflammatory Cytokine that Accelerates Development of Atherosclerosis(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- FRS-092 Cyclophilin A Promotes Angiotensin II-Induced Inflammation and Cardiovascular Hypertrophy in Mice(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of T
- OE-100 Role of Rho-kinase in the Pathogenesis of Coronary Hyperconstricting Responses Induced by Paclitaxel-Eluting Stent(OE17,Coronary Revascularization, PCI (Restenosis/Others/DES) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of
- Monte Carlo Simulator and Ancillary Response Generator of Suzaku XRT/XIS System for Spatially Extended Source Analysis
- Identification of endothelium-derived hyperpolarizing factor : an evolving concept on endothelium-derived relaxing factors
- PJ-417 Human Atrial Natriuretic Peptide Has the Protective Effect for Renal Function in Patients with Warm and Wet Heart Failure(Heart failure, clinical-13 (M) PJ70,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese C
- PE-008 Percutaneous Coronary Arterial Thrombectomy for AMI Protects Against LV Remodeling Related to the Proximal LAD and RCA(Acute myocardial infarction, clinical (diagnosis/treatment)-5 (IHD) PE2,Poster Session (English),The 70th Anniversary Annual Scie
- Diabetes Mellitus Causes Heart Failure due to Diastolic Dysfunction and Increases the Rate of readmission(Heart Failure, Clinical 15 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Percutaneous Coronary Arterial Thrombectomy for Acute Myocardial Infarction Reduces No-reflow and Protects Against LV Remodeling Related LAD Coronary Artery(Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 14 (IHD), The 69th Annual Scienti
- OE-107 Long-Term Inhibition of Rho-Kinase Suppresses Left Ventricular Remodeling After Myocardial Infarction in Mice(Heart Failure, Basic 1 (M) : OE13)(Oral Presentation (English))
- Disruption of Inducible Nitric Oxide Synthase Improved Beta-Adrenergic Inotropic Responsiveness but not the Survival of Cytokine-Induced Cardiomyopathy
- Suzaku Observations of the Hard X-Ray Variability of MCG -6-30-15 : the Effects of Strong Gravity around a Kerr Black Hole
- Thirty-Meter X-Ray Pencil Beam Line at the Institute of Space and Astronautical Science
- Suzaku Observations of the Cluster of Galaxies Abell 2052
- X-Ray Spectral Variability of the Seyfert Galaxy NGC 4051 Observed with Suzaku
- Suzaku Observation of 1H0707-495 : Puzzling Spectral Drop around 7keV(Chapter 10. Super Massive Black Holes, The Extreme Universe in the Suzaku Era)
- Estimation of Central Black Hole Masses in Low-Luminosity Active Galactic Nuclei
- Evidence for solar-wind charge-exchange X-ray emission from the earth's magnetosheath
- X-Ray Temperature and Mass Measurements to the Virial Radius of Abell 1413 with Suzaku
- Suzaku Observation of the Ophiuchus Galaxy Cluster : One of the Hottest Cool Core Clusters
- Performance of the Charge-Coupled Device for Direct X-ray Detection in the Energy Range of 1-9 keV at the Synchrotron Radiation Facility
- A Study of X-Ray Sources in the Central Region of NGC 1569 with Chandra(Poster)
- High Metallicity of the X-Ray Gas Up to the Virial Radius of a Binary Cluster of Galaxies : Evidence of Galactic Superwinds at High-Redshift
- Evidence for Solar-Wind Charge-Exchange X-Ray Emission from the Earth's Magnetosheath
- How Linearly Polarized Is the X-Ray Beam from the X-Ray Generator?
- Discovery of Short-Timescale Variability of Seyfert 2 Galaxy NGC 6300 with XMM-Newton(Poster)
- New Transient X-Ray Source in the Scutum Region Discovered with ASCA
- Suzaku Observation of Diffuse X-Ray Emission from the Open Cluster Westerlund 2 : a Hypernova Remnant?
- Spectral Statistics and Luminosity Function of a Hard X-Ray Complete Sample of Brightest AGNs(Poster)
- ASCA Observation of Unusually X-Ray-Hard Radio-Quiet QSO Kaz 102
- The Variable O VIII Warm Absorber in MCG-6-30-15
- X-Ray Color Movie Using the Charge-Coupled Device with a Direct X-Ray Detection Method
- Granulocyte Activation in Restenosis After Percutaneous Transluminal Coronary Angioplasty
- Acute renal failure associated with systemic capillary leak syndrome
- Suzaku Wide-Band X-Ray Observation of the Narrow-Line Seyfert 1 Galaxy Ton S180
- Discovery of Gas Bulk Motion in the Galaxy Cluster Abell 2256 with Suzaku
- Orbital Calibration of the XIS
- Evidence for solar-wind charge-exchange X-ray emission from the earth's magnetosheath
- Spectral Statistics and Luminosity Function of a Hard X-Ray Complete Sample of Brightest AGNs(Poster)
- Discovery of Short-Timescale Variability of Seyfert 2 Galaxy NGC 6300 with XMM-Newton(Poster)
- A Study of X-Ray Sources in the Central Region of NGC 1569 with Chandra(Poster)
- Intracellular Magnesium Deficiency in Acute Myocardial Infarction.
- Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope.