正常圧水頭症(第1報) : シャント術前後の脳血流量

概要

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Pre- and post-operative r-CBF was examined with the ^<133>Xe inhalation method in 11 patients of normal pressure hydrocephalus (NPH). In the effective shunt group consisting of 8 patients, the preoperative mean hemispheric CBF was slightly lower than normal, while depression of the r-CBF in the frontal and parietal lobes was considerable. However, in the non-effective shunt group consisting of 3 patients, the preoperative mean hemispheric CBF was significantly lower than normal, and the r-CBF in the frontal, parietal and temporal lobes was consistantly low. In the effective shunt group, about a 10% increase in the postoperative mean hemispheric CBF was noticed and the increased r-CBF was more prominent in the frontal and parietal lobes. However, the postoperative CBF did not increase in the non-effective shunt group. Improvement of symptoms did not always parallel the postoperatively increased mean hemispheric CBF. The possibility of predicting shunt effectiveness from the features of preoperative r-CBF study in NPH, the mechanism of the postoperative change in CBF, and the necessity of pathogenetic diagnosis of NPH for the evaluation of pre- and post-operative CBF study were discussed.
日本脳神経外科学会の論文
1982-06-15