Hollow-centered balloon catheterを用いた血栓形成による動脈瘤治療に関する実験的研究

概要

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Temporary intravascular occlusion of experimental aneurysms by hollow-centered balloon (HCB) catheter permitting blood flow through the main artery was studied in six canines. Of six experimental aneurysms of cervical arteries, which were made by the ligation of external carotid arteries, four aneurysms were thrombosed by HCB for 30 minutes to 120 minutes. The remaining two did not get thrombosed. One of the thrombosed aneurysms, which was occluded by HCB for 120 minutes, showed a complete occlusion of the cervical carotid artery. However, in the rest of the aneurysms, the internal carotid arteries were well demonstrated through HCB on angiograms. Due to occlusion by HCB the lumen of the internal carotid arteries was found dilated, and the endothelial cell layer was histologically compressed. HCB might be applied for clinical trial for inaccessible intracranial aneurysms, especially for giant aneurysms in the cavernous portion of the internal carotid artery, although further improvement of HCB is needed to be able to introduce it into the intracranial vessels without difficulty.
日本脳神経外科学会の論文
1987-05-15