PRIMARY MALIGNANT MELANOMA OF THE VULVA ASSOCIATED WITH PREGNANCY : CLINICAL, LIGHT AND ELECTRON MICROSCOPIC OBSERVATIONS
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概要
- 論文の詳細を見る
31歳の妊婦に発生した腟原発悪性黒色腫について,臨床的,光学顕微鏡的並びに電子顕微鏡的観察を行って次の如き知見を得たので報告する.息者は,妊娠第14週時に右小陰唇に黒褐色の小結節を指摘されたが,処置を受けなかった.妊娠第41週にて2,660gの女子を経腟分娩時に外陰のその病変部が生検された.組織学的診断は,Level V.の悪性黒色腫であつた.Radical vulvectomy並びにbnateral inguino-femoral lymphadenectomyが施行され,right inguinal lymph nodeに転移巣があった.この悪性黒色腫に対してDTIC,ACNU,VCRおよびOK432によるchemoimmunotherapyを実施した.さらに,電子顕微鏡観察において,黒色腫細胞の細胞質中に発育の種々なstagesにおける多数のmelanosomesおよびpremelanosomesが,透過型電子顕微鏡並びに走査型電子顕微鏡にょり認められた.本患者は,その診断23カ月後の現在臨床的に再発の所見は認められない.
- 社団法人日本産科婦人科学会の論文
- 1983-12-01
著者
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INOUE Satoru
Department of Neurosurgery, National Shizuoka Hospital
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Iwamasa Teruo
Department Of Clinical Chemistry And Pathology Shimonoseki Chuo General Hospital
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Fukuda Shigeru
Department Of Obstetrics And Gynecology Kumamoto University Medical School
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Iwamasa Teruo
Department Of Obstetricsgynecology And 'pathology Kumamoto University Medical School
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Maeyama Masao
Department Of Obstetics And Gynecology Kumamoto University Medical School
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Maeyama Masao
Department Of Obstetrics And Gynecology Kumamoto University Medical School
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MUNEMURA Masahide
Department of Obstetrics and Gynecology, Kumamoto University Medical School
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RlN Yasuo
Department of Obstetrics and Gynecology, Kumamoto University Medical School
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Rln Yasuo
Department Of Obstetrics And Gynecology Kumamoto University Medical School
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Munemura Masahide
Department Of Obstetrics And Gynecology Kumamoto University Medical School
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Inoue Satoru
Department Of Obstetrics And Gynecology Kumamoto University Medical School
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Inoue Satoru
Department Of Biology Faculty Of Science Kumamoto University
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MAEYAMA Masao
Department of Obstetrics and Gynecology, Kumamoto University Medical School
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