Dissociation of alterations in levels of myosin light chain kinase and cyclic AMP-dependent protein kinase in rabbit myometrium during pregnancy.
スポンサーリンク
概要
- 論文の詳細を見る
The alteration in levels of myosin light chain kinase and cyclic AMP-dependent protein kinase was studied in rabbit myometrium during pregnancy. The specific activity of myosin light chain kinase was 160.9±2.7, 128.1±3.5, and 126.5±4.4% at the 10th, 20th and 28th days after pregnancy, respectively, in comparison with the value seen in samples from non-pregnant rabbits. On the other hand, the specific activity of cyclic AMP-dependent protein kinase gradually decreased to 75.9±1.7, 58.7±3.5 and 36.9±1.9% of that of the control at each time with the increase in the time of gestation. The protein kinase inhibitor was not involved in the decrease in cyclic AMP-dependent protein kinase. These results suggest that the dissociation of the dynamic states of the two enzymes may make it possible for the myometrium to efficiently respond for contraction in the last stage of pregnancy.
- 社団法人 日本内分泌学会の論文
著者
-
Higashi Kenji
Department Of Materials Science Graduate School Of Engineering Osaka Prefecture University
-
Fukunaga Kohji
Department Of Pharmacology Graduate School Of Pharmaceutical Sciences Tohoku University
-
Miyamoto Eishichi
Department Of Electrical Engineering And Bioscience Graduate School Of Science And Engineering Wased
-
Maeyama Masao
Department Of Obstetics And Gynecology Kumamoto University Medical School
-
Maeyama Masao
Department Of Obstetrics And Gynecology Kumamoto University Medical School
-
Matsui Kazuo
Department Of Gynecology And Obstetrics Fukuda Hospital
-
FUKUNAGA Kohji
Department of Pharmacology, Kumamoto University Medical School
関連論文
- Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D2 and D3 Receptors
- Texture Randomization of AZ31 Magnesium Alloy Sheets for Improving the Cold Formability by a Combination of Rolling and High-Temperature Annealing
- Effect of Tool Materials on Dynamic Friction Characteristics and Microstructural Evolution at Elevated Temperature in Extruded AZ31 Magnesium Alloy
- Dissimilar Welding of Al and Mg Alloys by FSW
- Development of Constitutive Equation on Superplastic RS P/M Mg-Y-Zn Alloy
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions : Expression and Function of Forkhead Transcription Factors in Neurons
- Akt Is a Molecular Target for Signal Transduction Therapy in Brain Ischemic Insult
- Effect of Reduction Ratio of Hot-Extrusion on Microstructures of Superplastic Si_3N_4whisker/Al-Mg-Si Alloy Composites Studied by Transmission Electron Microscopy
- The Effect of Deformation Temperature on Microstructure and Superplastic Flow in Al-Cu-Mg/Si_3N_4p Composites
- Effect of Cell Size on the Dynamic Compressive Properties of Open-Celled Aluminum Foams
- The Critical Stress at the Interface for Cavity Nucleation in Superplastic Aluminum Matrix Composites Reinforced with Si_3N_4 Particles
- β-Amyloid Accumulation in Neurovascular Units Following Brain Embolism
- Development of a Closed Cell Aluminum Alloy Foam with Enhancement of the Compressive Strength
- Functional Proteins Involved in Regulation of Intracellular Ca^ for Drug Development : Role of Calcium/Calmodulin-Dependent Protein Kinases in Ischemic Neuronal Death
- High-Temperature Plastic Flow in Pre-Annealed Zr-Al-Ni-Cu Bulk Metallic Glass in a Supercooled Liquid Region
- Inhibition of Nitric Oxide Production and Protein Tyrosine Nitration Contribute to Neuroprotection by a Novel Calmodulin Antagonist, DY-9760e, in the Rat Microsphere Embolism(Pharmacology)
- Suppression of Macroscopic Defects through the Control of Friction between Workpiece and Dies in a Forged Magnesium Alloy Part with Ribs
- New Forming Process of Three-Dimensionally Shaped Magnesium Parts Utilizing High-Strain-Rate Superplasticity
- Secondary Processing of AZ31 Magnesium Alloy Concomitant with Grain Growth or Dynamic Recrystallization
- Plane-Strain Fracture Toughness on Thin AZ31 Wrought Magnesium Alloy Sheets
- The Grain Size Dependence on Diffusion Bonding Behavior in Superplastic Mg Alloys
- Experimental Study on Diffusion Bonding in Pure Magnesium
- The Post-ischemic Administration of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5, 6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e), a Novel Calmodulin Antagonist, Prevents Delayed Neuronal Death in Gerbil H
- Fracture Mechanism and Forming Limit in Deep-Drawing of Magnesium Alloy AZ31
- Effect of Small Addition of Zinc on Creep Behavior of Tin
- Effect of Pre-Introduced Shear Bands Direction on Deformation Behavior in Zr_Al_Ni_5Cu_ Bulk Metallic Glass
- Effect of Initial Grain Size on Dynamically Recrystallized Grain Size in AZ31 Magnesium Alloy
- Optimum Processing and Tool Controls for Three-Dimensional Friction Stir Welding
- Optimization of Welding Condition for Nonlinear Friction Stir Welding
- Optimization of Rolling Conditions in Mg-Al-Ca Alloy Containing Insoluble Second Phase Particles
- Effects of Size and Volume Fraction of Precipitated Crystalline Phase Induced by Friction Stir Processing on Hardness in Zr-Al-Ni-Cu Bulk Metallic Glass
- Cavitation Behavior in Superplastically Deformed Zn-22mass% Al Alloy at Room Temperature
- Energy Absorption in Closed-Cell Al-Zn-Mg-Ca-Ti Foam
- High-Strain-Rate Superplasticity in Metallic Materials and the Potential for Ceramic Materials
- Post-characteristics of Formed Zn-22 mass%Al Alloy to Seismic Damper for General Residence
- Room Temperature Deformation Behavior of Zn-22mass%Al Alloy with Nanocrystalline Structure
- Investigation on Dynamic Friction Properties of Extruded AZ31 Magnesium Alloy Using by Ring Upsetting Method
- Creep Deformation Mechanisms in Coarse-Grained Solid Solution Mg Alloys
- The Effect of Ram Speed on Mechanical and Thermal Properties in ECAE Process Simulation
- High Cycle Fatigue Property of Extruded Non-Combustible Mg Alloy AMCa602
- High Cycle Fatigue Property and Micro Crack Propagation Behavior in Extruded AZ31 Magnesium Alloys
- Characterization of αT3-1 Cells Stably Transfected with Luteininzing Hormone β-Subunit Complementary Deoxyribonucleic Acid
- Superplasticity at Room Temperature in Zn-22Al Alloy Processed by Equal-Channel-Angular Extrusion
- Pulmonary Fibrosis Associated with Polymyalgia Rheumatica
- Environmentally Friendly Composite Film of Anodizing and Electrodeposition Coating Having a High Corrosion Resistance on Magnesium Alloy AZ91D
- High Corrosion and Weather Resistant Anionic Resin Coating for 2014 T6 Aluminum Alloys Which Maintains Mirror Luster
- Optimization of Environmentally Friendly Anodic Oxide Film for Magnesium Alloys
- Elastic Constants of AlLi from First Principles
- Cold-Rolled Mg-14 mass%Li-1 mass%Al Alloy and Its Friction Stir Welding
- High-Strengthening of Mg-5.5mass%Y-4.3mass%Zn Cast Alloy by Friction Stir Processing
- Effect of Microstructural Change on High-Temperature Deformation in Pre-Annealed Zr_Al_Ni_Cu_ Bulk Metallic Glass
- Deformation Mechanism of Fine-Grained Superplasticity in Metallic Materials Expected from the Phenomenological Constitutive Equation
- Microstructure in Zn-Al Alloys after Equal-Channel-Angular Extrusion
- Materials Processing for Structural Stability in a ZK60 Magnesium Alloy
- Mechanical Properties of Mg-Y-Zn Alloy Processed by Equal-Channel-Angular Extrusion
- High-Strain-Rate Superplasticity in an AZ91 Magnesium Alloy Processed by Ingot Metallurgy Route
- Grain Size Control of Commercial Wrought Mg-Al-Zn Alloys Utilizing Dynamic Recrystallizaiton
- Effect of Grain Refinement on Tensile Ductility ZK60 Magnesium Alloy under Dynamic Loading
- Superplasticity of a Particle-Strengthened WE43 Magnesium Alloy
- Superplastic Deformation Behavior in Commercial Magnesium Alloy AZ61
- Low Temperature Superplasticity in a ZK60 Magnesium Alloy
- Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin
- Processing of Ductile Magnesium Alloy under Dynamic Tensile Loading
- Improvement of Crashworthiness in Ultra Lightweight Metallic Foam by Heat-Treatment for Microstructural Modification of Base Material
- Summary in the Project "Towards Innovation in Superplasticity"
- Ab Initio Calculation on the Structure and Elastic Properties of a Magnesium-Lithium Alloy
- Spatiotemporal expression of four isoforms of Ca^/calmodulin-dependent protein kinase I in brain and its possible roles in hippocampal dendritic growth
- Changes of Shape and Stress Distribution during Free Bulging in Axisymmetrically Blow-Formed Superplastic Sheet
- Novel Electroforming Process for Bulk Nanocrystalline Ni-W Alloys with Minimizing W-Concentration Gradient and Fluctuation
- Application of Electroforming Process to Bulk Amorphous Ni-W Alloy
- Effects of Flow Stress and Grain Size on the Evolution of Grain Boundary Microstructure in Superplastic 5083 Aluminum Alloy
- Ni-W Amorphous/Nanocrystalline Duplex Composite Produced by Electrodeposition
- Influence of Bath Composition on Tensile Ductility in Electrodeposited Bulk Nanocrystalline Nickel
- MALIGNANT DEGENERATION OF BENIGN CYSTIC TERATOMA OF THE BILATERAL OVARIES : ADENOSQUAMOUS CARCINOMA IN THE RIGHT TUMOUR AND SQUAMOUS CARCINOMA IN THE LEFT TUMOUR
- Effect of Titania Doping on Phase Stability of Zirconia Bioceramics in Hot Water
- Clarification of the Necessary Value of Surface Roughness for Developing Luster on an AZ31 Magnesium Alloy Surface with or without Acid Aqueous Solution Treatment
- Addition of an Aminic Antioxidant to a Hindered Ester-Based Heat Resisting Oil to Improve Lubrication for Press Forming of Magnesium Alloy Sheets
- Tribological Properties of Hybrid Process DLC Coating against Magnesium Alloy
- Optimization of Die Material and Its Surface Coating for Press Forming Magnesium Alloy
- Effect of Small Amount of Insoluble Dopant on Tetragonal to Monoclinic Phase Transformation in Tetragonal Zirconia Polycrystal
- A role of Ca^/calmodulin-dependent protein kinase II in the induction of long-term potentiation in hippocampal CA1 area
- Surface Treatment to Provide a Metallic Luster to AZ31 Magnesium Alloy
- Experimental Investigation of Cavitation Behavior in AZ61 Magnesium Alloy
- High-Strain-Rate Superplasticity and Its Applications
- Cardioprotection by Vanadium Compounds Targeting Akt-Mediated Signaling
- A working model of CaM kinase II activity in hippocampal long-term potentiation and memory
- Current Studies on a Working Model of CaM Kinase II in Hippocampal Long-Term Potentiation and Memory
- Special Issue on Platform Science and Technology for Advanced Magnesium Alloys IV
- Rolling Texture Evolution of AZ31 Magnesium Alloy Sheets by Isothermal Eccentric-Rolls Drawing
- PREFACE
- PREFACE
- The Optimal Surface Roughness Condition on Diffusion Bonding
- Dynamic Friction Properties and Microstructural Evolution in AZ31 Magnesium Alloy at Elevated Temperature during Ring Compression Test
- PREFACE
- The Post-ischemic Administration of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a Novel Calmodulin Antagonist, Prevents Delayed Neuronal Death in Gerbil Hi
- Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders : Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D_2 and D_3 Receptors
- Regulation by estrogen and progesterone of protein kinases in rabbit myometrium.
- Dissociation of alterations in levels of myosin light chain kinase and cyclic AMP-dependent protein kinase in rabbit myometrium during pregnancy.
- Interaction of PICK1 with C-Terminus of Growth Hormone–Releasing Hormone Receptor (GHRHR) Modulates Trafficking and Signal Transduction of Human GHRHR
- The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation