1歳未満で診断された神経芽腫537例の検討 : 第1編:臨床像について

概要

論文の詳細を見る
To recommend therapeutic regimen for neuroblastoma patients diagnosed before 1 year of age, we conducted a survey for clinical characteristics and present status of treatment in the patients through a questionaire all over Japan. 537 cases were registered. 314 were male and 223 were female. 355 cases were detected asymptomatically by mass screening. 45 were detected incidentally by physical findings at medical examination. 137 were diagnosed by clinical symptoms. The site of primary tumor was abdomen in 456 cases (including the adrenal gland in 275 and retroperitoneum in 156) , followed by mediastinum in 62 and neck in 11. There was no characteristic primary site for all of these cases. The extent of diseases at diagnosis was Stage I (141) , Stage II (154) , Stage III (92) , Stage IV A (37) , Stage IV B (34) , Stage IV S (73) , and unknown stages (6) . 77% of the cases detected by mass screening were in Stage I, II or IV S, and 23% were in Stage III, IV A or IV B. 53% of the others were in Stage I, II or IV S, and 45% were in Stage III, IV A or IV B. 50% of the cases diagnosed by clinical symptoms were in Stage III, IV A or IV B.
日本小児外科学会の論文
1992-12-20