新生児の Gastroesophageal Reflux (GER)

概要

論文の詳細を見る
Thirty three cases of GER in newborn infants were reviewed. Manometric study (23 cases), 24 hour pH monitoring (23 cases) and endoscopy (33 cases) were done at admission and repeated three weeks later. Twenty seven patients were followed from one month to 8 years. Male and female ratio was 17 : 16, 27 cases (80%) had symptoms before 72 hours after birth. Severe esophagitis with ulcer and erosion was found in 25 cases and equally frequent with or without hiatus hernia (HH). But pH score was significantly higher in patient with HH. Twelve cases of GER without HH healed in one month and no one needed surgery. In GER with HH, vomiting disappeared between 3 and 12 months (mean 5.2 months) and reflux under fluoroscopy disappeared between 3 and 14 months (mean 7.6 months). One patient with HH underwent surgery because of failure to thrive and persisting esophagitis. The prognosis of GER in newborn period is much better than expected, and medical therapy is tried while the symptoms and results of examination are improving.
日本小児外科学会の論文
1992-06-20