神経芽細胞腫の特性に関する研究(第三報) : 初診時年齢と性別,原発腫瘍発生部位,組織型等17因子間からみた2年以上生存率および発生頻度の検討

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Study Group on Neuroblastoma in 1977 and 1978, granted by the Ministry of Health and Welfare This study included 330 cases of neuroblastoma, excluding 24 cases of ganglineuroma and 26 cases of neuroblastoma under 2 years of follow-up period, that our research group experienced in 11 facilities. We investigated on the occurrence rate and survival rate of these 330 cases from the analysis, on the relationship between the age and the various factors, such as the histological type, the site of origin, the site of metastasis and the results of hematological and chemical examinations. We summerized some new facts as follows: (1) The survival rate of the group over 4 years of age in the initial exmination was significantly higher than that between 3 and 4 years. (2) The survival rate of female was significantly higher than male. (3) The age distribution among the tumor of adrenal origin gave a convex type with a peak between 12 and 18 months. (4) The rosette forming type in histology had lower occurrence rate in accordance with age, while the round cell type had higher occurrence. (5) The survival rate of the H_3, D_2 group with the more advanced metastasis of liver and skin was higher than that of the H_1, H_2, D_0 group with the less advanced metastasis. Seventy per cent of the H_3, D_1, D_2 group, occured in the age under 6 months of age, with better prognosis. (6) The groupwith the preoperative positive urinary VMA had higher survival rate than that with negative urinary VMA. This was reversal among the cases between 1 and a half and 4 years of age. The ratio with positive urinary VMA had a tendency of increase in accordance with age.
日本小児外科学会の論文
1980-02-20

神経芽細胞腫の特性に関する研究(第三報) : 初診時年齢と性別,原発腫瘍発生部位,組織型等17因子間からみた2年以上生存率および発生頻度の検討

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