EFFECTS OF NIVALENOL ON THE BONE MARROW IN MICE
スポンサーリンク
概要
- 論文の詳細を見る
In order to investigate the toxic effects of nivalenol, one of the trichothecene mycotoxins, we performed a short-term feeding trial for 24 days using feed supplemented with rice artificially molded with nivalenol producing fungus, Fusarium nivale Fn 2B, in female C57BL/6CrSlc SPF mice. A significant erythropenia and slight leukopenia were observed in the 30 ppm group, but no marked changes were observed in other hematological parameters, feed consumption, body weight gain, or weights of the liver, spleen, and thymus. Ultrastructural studies also revealed polyribosomal breakdowns of the bone marrow cells in the 30 ppm group.
- 日本トキシコロジー学会の論文
- 1987-02-25
著者
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UENO Yoshio
Department of Toxicology and Microbial Chemistry, Faculty of Pharmaceutical Sciences, Science Univer
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MORI Mayumi
Department of Hematology, Tokyo Metropolitan Geriatric Hospital
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Mori Mayumi
Department Of Hematology Tokyo Metropolitan Geriatric Hospital
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Ryu Jae-chun
Department Of Toxicology And Microbial Chemistry Faculty Of Pharmaceutical Sciences Science Universi
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IZUMIYAMA Naotaka
Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology
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Tanaka Toshitsugu
Division Of Food Chemistry Public Health Research Institute Of Kobe City
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Mori Mayumi
Life Science Research Center Shiseido Co. Ltd.
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OHTSUBO Kohichiro
Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology
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UENO Yoshio
Tochigi Institute of Clinical Pathology
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Ueno Y
Department Of Toxicology And Microbial Chemistry Faculty Of Pharmaceutical Sciences Science Universi
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Ueno Yoshio
Department Of Toxicology And Microbial Chemistry Faculty Of Pharmaceutical Sciences
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Izumiyama Naotaka
Department Of Clinical Pathology Tokyo Metropolitan Institute Of Gerontology
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Ohtsubo K
Tokyo Metropolitan Inst. Gerontology Tokyo Jpn
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Ohtsubo Kohichiro
Department Of Clinical Pathology Tokyo Metropolitan Institute Of Gerontology
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Mori Mayumi
Department Of Anesthesiology School Of Medicine Fukuoka University
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Ueno Yoshio
Department Of Applied Chemistry Nagoya Institute Of Technology
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