病院薬学研究へのインジウム-113mおよびテクネチウム-99m標識放射性薬剤の利用

概要

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Radioactive compounds as the radiopharmaceuticals, ^<113m>In-EDTA sterile solution, ^<113m>In. Fe(OH)_3-aggregate sterile suspension of the various particle sizes and ^<113m>In-GSH sterile solution were prepared for the general method of injection preparation and Kit systems as simplified methods, These sterile solutions were tested with animals and human subjects as scanning agents of brain, kidney, blood pool, lung, bone marrow, liver and spleen. The use of ^<113m>In and ^<99m>Tc to the pharmaceutics has included radioactive tracers of the components of various solid dosage forms and suppositories, For example, these are as follows; application of ^<113m>In for measurement of the degree of mixing, characteristics of the rectal suppositories in the release of ingredients as determined with ^<99m>Tc, and scintigraphical methods for evaluation of tablets and capsules in the gastrointestinal tract.
日本医療薬学会の論文
1992-06-20