1 ヒト口腔扁平上皮癌におけるモノクローナル抗体 (E8およびP54) 対応抗原の局在性 (第413回大阪歯科学会例会)

概要

論文の詳細を見る
The staining ability of the monoclonal antibodies (MoAbs) E 8 and P 54 was evaluated by light and electron microscopy using formalin-fixed, paraffin-embedded sections and fresh frozen sections of oral squamous cell carcinomas. E 8 and P 54 produced positive staining in the cell membrane of normal and neoplastic stratified squamous epithelia. Although E 8 and P 54 microscopically reacted throughout the cell membrane, they showed different localizations ultrastructurally. E 8 reactivity was evident throughout the cell membrane of normal and neoplastic stratified squamous epithelia, but staining with P 54 was localized around the desmosomes. These MoAbs may be useful in the investigation of oral epithelium and squamous cell carcinoma.
大阪歯科学会の論文
1992-06-25