抗変異原に関する研究(特別企画「食品ならびに食品成分による抗変異原性作用」)

概要

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In recent years, because people have become more health and lifespan concious, interest has increased over how to prevent life-style related diseases, including cancer, by consuming daily foods or supplements. It is well known that several mutagens play an important role in the early stage of carcinogenesis. Therefore, intake of antimutagens should be effective in reducing cancer incidence and mortality. In this article, many experimental studies on antimutagens are reviewed. These chemicals have been isolated mainly from vegetables and fruits, and their antimutagenic activity studied in vitro with bacteria, yeast, and cultured animal cells, and in vivo in rats and mice. The mechanism of action of antimutagens in inhibiting carcinogenesis is also discussed. As recommended by the World Cancer Research Fund and the American Institute for Cancer Research, proper intake of vegetables and fruits might be a useful and important means for prevention of cancers.
日本環境変異原学会の論文
2002-11-13