<原著>Sodium tellurite投与による実験的う歯の発生と口腔内レンサ球菌叢の変動に関する研究

概要

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In rats fed on a diet containing sodium tellurite, an increase in dental caries and a change in oral streptococcal flora was observed. Dental caries developed in both the control and tellurite group, but a clear increase was seen in the latter over the former. Simultaneously, a change in proliferation of oral streptococcal flora was seen : namely, Streptococcus(S.) mulans was isolated in all plaque samples from pits and fissures of the control and tellurite groups, but the ratio of S. mutans to total streptococci was lower in the tellurite group. On the other hand, S. salivarius was detected from all tellurite rats, but not from the control. It was also shown that S. salivarius was more resistant to sodium tellurite than S. mutans in vitro. Furthermore, S. milleri was isolated at a higher rate in the tellurite group than in the control group. From the above, it was clear that, after administration of sodium tellurite, both a qualitative and a quantitative change of oral streptococcal flora occurred. This change of flora is probably related to the increase of dental caries in the tellurite group.
北海道医療大学の論文
1985-06-30