<症例>胃癌に合併した黒色表皮腫の3例

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Three cases are reported with acanthosis nigricans associated with gastric cancer ; they account for 0.6% of all patients diagnosed as gastric cancer in the First Department of Surgery in the last 10 years. Case 1 : A 45-year-old female was admitted to our hospital with the chief complaints of itching and hyperpigmentation of the axilla. At the Department of Dermatology, these changes were considered to be due to malignant acanthosis nigricans. Gastric cancer (Borr. 3) was discovered by radiological and endoscopical examinations. At laparotomy a marked invasion into the liver and pancreas was found, so no resection could be performed. After the operation, the skin lesions improved by chemotherapy. Case 2 : A 54-year-old female was admitted to this hospital with a complaint of hyperpigmentation of her inguinal region. At the Department of Dermatology, this change was considered to be due to malignant acanthosis nigricans. By X-ray and endoscopic examinations of the stomach, advanced gastric cancer (Borr. 4) was discovered. At laparotomy a marked lymph node metastases were found, so curative operation could not be performed. Five months after the operation, bone metastasis was detected. The skin lesions were not changed. Case 3 : A 72-year-old male underwent distal gastrectomy, under a diagnosis of gastric cancer (Borr. 2). However, curative resection was impossible on account of advanced cancer. After the operation, hyperpigmentation of his hands and feet was seen. At the Department of Dermatology these changes were considered to be due to malignant acanthosis nigricans. The skin lesions improved by chemotherapy.
近畿大学の論文
1985-12-25

<症例>胃癌に合併した黒色表皮腫の3例

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