Emphysematous Cystitis in a Chemically-Induced Diabetic Dog
スポンサーリンク
概要
- 論文の詳細を見る
Emphysematous cystitis is a rare disorder caused by bacterial infection and characterized by gas accumulation within the bladder wall with cyst formation. This report describes the histopathological characteristics of emphysematous cystitis found in a diabetic female beagle induced by streptozotocin and alloxan. Macroscopically, multiple cyst-like structures were observed on the cut surface of the urinary mucosa. During fixation, small specimens cut from the mucosa floated on the surface of the fixative solution. Histopathologically, multiple cysts were lined with a single layer of flattened cells found to be immunohistochemically positive for vimentin, partially positive for α-smooth muscle actin or macrophage scavenger receptor, class A, and thought to be myofibroblasts, fibroblasts or macrophages. Multinucleated giant cells were observed around the cysts, and gram-negative short bacilli were observed in the lumen of the urinary bladder. From these findings, this case was diagnosed as emphysematous cystitis.
- 日本毒性病理学会の論文
- 2009-12-01
著者
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鈴木 雅実
Safety Assessment Dep. Fuji Gotemba Res. Laboratories Chugai Pharmaceutical Co. Ltd.
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鈴木 雅実
Safety Assessment Department Chugai Pharmaceutical Co. Ltd.
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Adachi Kenji
Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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Miyoshi Akio
Safety Assessment Department, Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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KATO Atsuhiko
Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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Kato Atsuhiko
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Hayashi Shuji
Safety Assessment Department Chugai Pharmaceutical Co. Ltd.
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Miyoshi Akio
Safety Assessment Department Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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鈴木 雅実
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Adachi Kenji
Toxicology Laboratory Chugai Pharmaceutical Co. Ltd.
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Matsuo Saori
Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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Miyoshi Akio
Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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Kato Atsuhiko
Safety Assessment Department Chugai Pharmaceutical Co. Ltd.
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Kato Atsuhiko
Safety Assessment Laboratory Chugai Pharmaceutical Co. Ltd.
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Suzuki Masami
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Watanabe Takeshi
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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Hayashi Shuji
Fuji Gotemba Research Laboratories Chugai Pharmaceutical Co. Ltd.
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