Introduction of both D-Amino Acids and Arg-Residues into Cationic Cytotoxic Peptides and Their Selectivity for Normal and Cancer Cells
スポンサーリンク
概要
- 論文の詳細を見る
- 2008-03-01
著者
-
LEE Sannamu
Department of Chemistry, Faculty of Science, Fukuoka University
-
IDE HIROKO
Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University
-
KUROKI Motomu
Department of Biochemstry, Fukuoka University School of Medicine
-
Ide Hiroko
Department Of Chemistry Faculty Of Science Fukuoka University
-
Lee Sannamu
Department Of Chemistry Faculty Of Science Fukuoka University
-
Kuroki Masahide
Department Of Biochemistry Cancer Research Institute
-
Kuroki Motomu
Department Of Biochemistry School Of Medicine Fukuoka University
-
Kuroki Motomu
Department Of Biochemistry Faculty Of Medicine Fukuoka University
-
Lee Sannamu
Department Of Chemistry Faculty Of Science School Of Medicine Fukuoka University
-
TOKUNAGA Ikuko
Department of Chemistry, Faculty of Science, Fukuoka University
-
TAKENOSHITA Hiroko
Department of Chemistry, Faculty of Science, Fukuoka University
-
Tokunaga Ikuko
Department Of Chemistry Faculty Of Science Fukuoka University
-
Kuroki Masahide
Department Of Biochemistry School Of Medicine Fukuoka University
-
Takenoshita Hiroko
Department Of Chemistry Faculty Of Science Fukuoka University
関連論文
- Effect of Hydrophobic Core Amino Acid Residues of P53 Oligomerization Domain on the Stability of Three-Dimensional Structure
- Study on Association Factor Using the Substituted Analogs of Tetramerization Domain of Tumor Suppressor Protein p53
- DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae
- USEFUL ENDOSCOPIC ULTRASONOGRAPHY TO ASSESS THE EFFICACY OF NEOADJUVANT THERAPY FOR ADVANCED ESOPHAGEAL CARCINOMA : BASED ON THE RESPONSE EVALUATION CRITERIA IN SOLID TUMORS
- Preoperative Evaluation of Lymph Node Metastasis in Esophageal Cancer
- Expression of apoptosis-related proteins (p53, p21^, bcl-2, and bax) and sensitivity to chemotherapy in squamous cell carcinoma of the esophagus
- Analysis of Postoperative Complications after Esophagectomy for Esophageal Cancer in Patients receiving Neoadjuvant Therapy
- An Evaluation of the Efficacy of Preoperative Therapy for Thoracic Esophageal Carcinoma Using Endoscopic Ultrasonography
- Expression of p53 Protein Related to Human Papillomavirus and DNA Ploidy in Superficial Esophageal Carcinoma
- Synthesis of Second Transmembrane Segment Peptides in Band 3 Protein from Human Erythrocyte Membrane and Their Interaction with Model Membranes
- A Monoclonal Antibody Modulates Neutrophil Adherence While Enhancing Cell Motility
- Measurement of circulating biliary glycoprotein (CD66a) in liver diseases
- Interaction if the Fragments Characteristic of Bactenecin 7 with Phospholipid Bilagyers and Their Antimicrobial Activity
- Amyloid Formation and Cytotoxicity of a De Novo Designed Protein, Amyloidgenesin, and Its Analogs
- Granulocyte and Monocyte Adsorption Apheresis Therapy for Ulcerative Colitis Patients : A Useful Tool for Surgical Indication Assessments
- Structure and Bilogical Activity of the Neuropeptide γ
- Purification and Characterization of a Novel Antimicrobial Peptide from the Skin of Hagfish, Eptatretus Burgeri.
- Secondary Structures of Synthetic Peptides Corresponding to the First Membrane-Contact Portion of Normal Band 3 and Its Deletion Mutant (Southeast Asian Ovalocytosis)
- Nanotubular Structure Formation by a De Novo-designed Amphiphilic α-Helical Peptide, Hel 13-5, and Various Biomembrane-specific Lipids
- The Effect of D-Amino Acid-Containing Basic Peptides with Different Hydrophobicity on the Antimicrobial and Cytotoxic Activity
- FIBRIL STRUCTURE FORMED BY THE INTERACTION OF AN AMPHIPHILIC α-HELICAL PEPTIDE, HEL 13-5, AND ITS ANALOGS WITH PHOSPHOLIPIDS
- INTERACTION OF AMYLOID β-PEPTIDE (1-40) WITH A LIPID-MIXTURE HAVING BRAIN MEMBRANE-LIKE LIPID COMPOSITION
- 各種胆汁酸から合成したカチオン活性剤のミセル形成に関する熱力学的研究
- Synthesis of Mutants of Lipophilic Core in a De Novo Designed Small Globular Protein (SGP) and Their Interactions with Lipid-and Bio-Membranes
- Structure and Activity Relationship of D-Amino Acid Incorporated Antimicrobial Model Peptides
- Morphological Change of Acidic and Neutral Liposomes Induced by Basic Amphiphilic α-Helical Pepties with Systematically Varied Hydrophobic Hydrophilic Balance
- N- and C-Terminal Effect of Amphiphilic α-Helical Peptides on the Interaction with Model- and Bio-Membranes
- Effect of Amphiphilic α-Helical Model Peptides with Systematically Varied Hydrophobic-Hydrophilic Balance on the Interaction with the Lipid Bilayers
- De Novo Design, Synthesis and Characterization of Three Analogs Related to a Pore-Forming Small Globular Protein (SGP)
- Effect of N- and C-Termini Blocked and Both-Terminal Free Amphiphilic Peptides on Interaction with Model- and Bio-Membranes
- Translocation of a Mimic Little Super Protein (LSP) from Aqueous Solution into Lipid Bilayers
- De Novo Synthesis of a Little Super Protein (LSP) with a Hydrophobic Helix Surrounded by Three Basic Amphiphilic Helices and Its Solution Property
- Interaction of Mastoparan B and Its Ala-Substituted Analogs with Phospholipid Bilayers
- Design and Synthesis of Amphiphilic α-Helical Model Peptides with Various Hydrophobic-Hydrophilic Balances and Their Interaction with Lipid- and Biomembranes
- Structure-Activity Relationships of Tachykinin Peptides Derived from Fish
- The Effect of Peptide Chain Length on the Nanotubular Structure Formed by the Interaction of an Amphiphilic α-Helical Peptide, Hel 13-5, with Phospholipid
- Molecular Mechanism of Liposome Membrane Fusion Induced by Amphipathic Helical Peptides
- Design and Synthesis of Arg-Containing Peptides Having Various Secondary Structures and Their Biological Activities
- Thoracic and Cardiovascular Surgery in Japan during 1999 : Annual Report by The Japanese Association for Thoracic Surgery
- Thoracic and Cardiovascular Surgery in Japan During 1997 : Annual Report by the Japanese Association for Thoracic Surgery
- Antitumor activity of chimeric immunoreceptor gene-modified Tc1 and Th1 cells against autologous carcinoembryonic antigen-expressing colon cancer cells
- Interaction Analysis of the Carcinoembryonic Antigen (CEA) with Its Monoclonal Antibody Immobilized on a Gold Surface Using Fourier Transform Infrared Reflection-Absorption Spectroscopy (FT-IR RAS)
- Design and Synthesis of an Oxidation-Responsible Amyloid Fibril Formation Protein, AG-Met
- Nanotubule Formed by a Hydrophobic Amphiphilic α-Helical Peptide and Natural Phospholipids and Its Application
- Effect of Cholesterol on Amyloid Beta-Peptide Deposition in Liposomes Prepared by Brain Membrane-Like Lipid
- Mechanism of Neutral Liposome Membrane Fusion Induced by the Two Charge-Reversed Amphipathic Helical Peptides
- Synthesis of Mutants of a De Novo Designed Amyloid-forming Protein, Amyloidgenesin, and Their Amyloid-Forming Abilities
- A De Novo Designed α-to-β Transition Protein with an Amyloid Fibril Formation
- In vitro biophysical activities of newer all-synthetic surfactant composed of mixture of soybean PC or soybean PC-peptide
- Development of Low Cost Pulmonary Surfactant Composed of a Mixture of Lipids or Lipids-Peptide
- Introduction of both D-Amino Acids and Arg-Residues into Cationic Cytotoxic Peptides and Their Selectivity for Normal and Cancer Cells
- Substitution of Arg Residues for Lys Resudues in a Cationic Anti-Tumor Peptide Containing D-Amino Acids and Cytotoxicities
- Effect of Innovation of D-amino Acids into Novel Anti-Tumor Peptide and Protein on their Conformation and Cytotoxicities
- Synthesis of Transmembrane Segment Peptides and Its Analogs of A Single Spanning Protein, Isk, Forming Potassium Channel and Its Channel Formation Activity
- Studies on Association Behavior of Transmembrane Segment of Influenza Virus M2 Protein in Lipid Bilayers
- Thoracic and Cardiovascular Surgery in Japan during 2000 : Annual Report by The Japanese Association for Thoracic Surgery
- Dialysis-based Bioreactor System for the Production of Chimeric Antibodies : an Alternative to Ascites Production in Mice
- Inhibition of the Proliferation of a Malignant Peripheral Nerve Sheath Tumor Cell Line by Gamma Interferon Gene Transfection
- Comparison of Extended Esophagectomy through Mini-thoracotomy/laparotomy with Conventional Thoracotomy/laparotomy for Esophageal Cancer
- Amphiregulin regulates the activation of ERK and Akt through epidermal growth factor receptor and HER3 signals involved in the progression of pancreatic cancer
- Thoracic and Cardiovascular Surgery in Japan During 1998 Annual Report by the Japanese Association for Thoracic Surgery
- ASSOCIATION MODE OF A TRANSMEMBRANE α-HELICAL MODEL PEPTIDE, p24, AND ITS ANALOGS IN PHOSPHOPLIPID BILAYERS
- The Effect of Ion on the Stability of Three Dimensional Structure of Tumor Suppressor Protein, p53, Oligomerization Domain in Solution
- Reactivity of Direct Assays for Low-Density Lipoprotein (LDL) Cholesterol Toward Charge-Modified LDL in Hypercholesterolemia
- Antibacterial activity of amphipathic basic peptides with a long acyl group and their interaction with phospholipid bilayers.
- Therapeutic Approaches to the Regulation of Metabolism of High-Density Lipoprotein:– Novel HDL-Directed Pharmacological Intervention and Exercise –
- P23. Sonodynamic cancer therapy using low-intensity ultrasound with novel porphyrin derivatives(Poster Presentation)
- Secondary Structures of Synthetic Peptides Corresponding to the First Membrane-Contact Portion of Normal Band 3 and Its Deletion Mutant (Southeast Asian Ovalocytosis).