The Effect of D-Amino Acid-Containing Basic Peptides with Different Hydrophobicity on the Antimicrobial and Cytotoxic Activity

スポンサーリンク

概要

• 論文の詳細を見る
• Chemical Society of Japanの論文
• 2000-10-15

著者

• Sugihara Gohsuke

  Department of Chemistry, Faculty of Science, Fukuoka University

• LEE Sannamu

  Department of Chemistry, Faculty of Science, Fukuoka University

• KIYOTA Taira

  Department of Chemistry, Faculty of Science, Fukuoka University

• OKA Masahito

  Research Institute for Advanced Science and Technology, Osaka Prefecture University

• Sugihara Gohsuke

  Department Of Chem.istry Faculty Of Science Fukuoka University

• Kiyota Taira

  Department Of Chemistry Faculty Of Science Fukuoka University

• Lee S

  Department Of Chemistry Faculty Of Science Fukuoka University

• Lee Sannamu

  Department Of Chemistry Faculty Of Science Fukuoka University

• YANAGIDA Ryoko

  Department of Chemistry, Faculty of Science, Fukuoka University

• MIYOSHI Mie

  Pharmaceutical Research Division, Yoshitomi Pharmaceutical Industries, Ltd.

• Oka Masahito

  Research Institute For Advanced Science And Technology Osaka Prefecture University

• Matsutani M

  Pharmaceutical Research Division Yoshitomi Pharmaceutical Industries Ltd.

• Yanagida Ryoko

  Department Of Chemistry Faculty Of Science Fukuoka University

関連論文

• Solubilization of Sterols by Bile Salt Micelles and Monolayer Behavior of Mixed Systems of a Bile Acid with Different Sterols
• Effect of Hydrophobic Core Amino Acid Residues of P53 Oligomerization Domain on the Stability of Three-Dimensional Structure
• Study on Association Factor Using the Substituted Analogs of Tetramerization Domain of Tumor Suppressor Protein p53
• Micelle Formation of Phosphate-Type Hybrid Surfactants in Aqueous Solution
• Synthesis of Second Transmembrane Segment Peptides in Band 3 Protein from Human Erythrocyte Membrane and Their Interaction with Model Membranes
• Interaction if the Fragments Characteristic of Bactenecin 7 with Phospholipid Bilagyers and Their Antimicrobial Activity
• Structure and Function of Pro/Arg-rich Repeated Region in Antibiotic Bactenecin 5
• Amyloid Formation and Cytotoxicity of a De Novo Designed Protein, Amyloidgenesin, and Its Analogs
• Structure and Bilogical Activity of the Neuropeptide γ
• Purification and Characterization of a Novel Antimicrobial Peptide from the Skin of Hagfish, Eptatretus Burgeri.
• Secondary Structures of Synthetic Peptides Corresponding to the First Membrane-Contact Portion of Normal Band 3 and Its Deletion Mutant (Southeast Asian Ovalocytosis)
• Nanotubular Structure Formation by a De Novo-designed Amphiphilic α-Helical Peptide, Hel 13-5, and Various Biomembrane-specific Lipids
• The Effect of D-Amino Acid-Containing Basic Peptides with Different Hydrophobicity on the Antimicrobial and Cytotoxic Activity
• FIBRIL STRUCTURE FORMED BY THE INTERACTION OF AN AMPHIPHILIC α-HELICAL PEPTIDE, HEL 13-5, AND ITS ANALOGS WITH PHOSPHOLIPIDS
• INTERACTION OF AMYLOID β-PEPTIDE (1-40) WITH A LIPID-MIXTURE HAVING BRAIN MEMBRANE-LIKE LIPID COMPOSITION
• 各種胆汁酸から合成したカチオン活性剤のミセル形成に関する熱力学的研究
• Synthesis of Mutants of Lipophilic Core in a De Novo Designed Small Globular Protein (SGP) and Their Interactions with Lipid-and Bio-Membranes
• Structure and Activity Relationship of D-Amino Acid Incorporated Antimicrobial Model Peptides
• Morphological Change of Acidic and Neutral Liposomes Induced by Basic Amphiphilic α-Helical Pepties with Systematically Varied Hydrophobic Hydrophilic Balance
• N- and C-Terminal Effect of Amphiphilic α-Helical Peptides on the Interaction with Model- and Bio-Membranes
• Effect of Amphiphilic α-Helical Model Peptides with Systematically Varied Hydrophobic-Hydrophilic Balance on the Interaction with the Lipid Bilayers
• De Novo Design, Synthesis and Characterization of Three Analogs Related to a Pore-Forming Small Globular Protein (SGP)
• Effect of N- and C-Termini Blocked and Both-Terminal Free Amphiphilic Peptides on Interaction with Model- and Bio-Membranes
• Translocation of a Mimic Little Super Protein (LSP) from Aqueous Solution into Lipid Bilayers
• De Novo Synthesis of a Little Super Protein (LSP) with a Hydrophobic Helix Surrounded by Three Basic Amphiphilic Helices and Its Solution Property
• Interaction of Mastoparan B and Its Ala-Substituted Analogs with Phospholipid Bilayers
• Design and Synthesis of Amphiphilic α-Helical Model Peptides with Various Hydrophobic-Hydrophilic Balances and Their Interaction with Lipid- and Biomembranes
• Structure-Activity Relationships of Tachykinin Peptides Derived from Fish
• The Effect of Peptide Chain Length on the Nanotubular Structure Formed by the Interaction of an Amphiphilic α-Helical Peptide, Hel 13-5, with Phospholipid
• Molecular Mechanism of Liposome Membrane Fusion Induced by Amphipathic Helical Peptides
• Theoretical Analysis of β-Hairpin Structure
• Six-β-Strand Bundle Structure. A New Super Secondary Structure Constructed by Anti-Parallel Packing of Six b-Strands
• Design and Synthesis of Arg-Containing Peptides Having Various Secondary Structures and Their Biological Activities
• Conformation Study on Poly(tripeptide)s Composed of Pro, Asp and Ala Residues
• Conformation Study on Poly(tetrapeptide)s Composed of Pro, Asp and Ala Residues
• Conformation Analysis of Proline-rich Oligopeptides
• Cell-Attachment Activities of Surface Immobilized RGDS Mimetic Oligopeptides
• Solution Property of Copolypeptides Having Pro Residue as the Major Component
• Conformational Analysis of Model Polypeptides Having Repetitive Glu-Pro-Pro-Pro Sequences
• Conformational Analysis of Model Polypeptides Having Repetitive Xaa-Pro-Pro Sequences
• Conformational Analysis of Model Repetitive Polypeptides Poly(Xaa-Pro)
• Conformational Analysis of Model Polypeptides Having Repetitive Xaa-Pro Sequences
• Synthesis of Arg-Gly-Asp-Ser Mimetic Oligopeptides and Evaluation of Their Cell-Attachment Activity
• Thermal Property of Proline Copolypeptide
• Theoretical Analysis of α-Hairpin Structure
• Conformational Analysis of Model Polypeptides Having Repetitive Ala-Pro-Pro-Pro Sequence
• Conformational Analysis of Oligopeptides Containing Serine Residue as One Component
• SYNTHESIS AND CONFORMATIONAL ANALYSIS OF MODEL PEPTIDES HAVING REPETITIVE XAA-PRO-PRO SEQUENCES
• Theoretical Conformational Analysis on the Turn Portion of Tachyplesin I Based on the Ala-Residue Approximation
• Synthesis and Conformational Analysis on Model Polypeptides for Repetitive Portion of Amelogenin from Bovine Tooth Enamel
• Theoretical Analysis of β-Hairpin Structures Stabilized by a Disulfide-linkage between Two Strands
• Theoretical Analysis of α-Hairpin Structures Stabilized by a Disulfide-linkage between Two Helices
• Theoretical Analysis of α-Hairpin Structures Stabilized by Electrostatic Interactions between Two Charged Residues
• Theoretical Conformational Analysis of Disulfide-Linked Tetrapeptides Ac-Cys-Pro-Xaa-Cys-NHMe Having Hydrophobic Xaa Amino-Acid Residues
• Conformational Analysis Based on Molecular Mechanics Calculations of Model Poly(hexapeptide) for Repetitive Portion of γ-Zein
• Theoretical Analysis of x-Helix Hairpin Structures Constructed by Two Right-Handed x-Helices
• Enthalpy-Entropy Compensation Rule and the Compensation Temperature Observed in Micelle Formation of Different Surfactants in Water. What is the so-called Compensation temperature?
• Transport Behavior of Lipids Solubilized by Bile Salts across Porous Membranes
• Design and Synthesis of an Oxidation-Responsible Amyloid Fibril Formation Protein, AG-Met
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water. IV. Three Combinations of SDS with MEGA-8, -9 and -10
• Nanotubule Formed by a Hydrophobic Amphiphilic α-Helical Peptide and Natural Phospholipids and Its Application
• Effect of Cholesterol on Amyloid Beta-Peptide Deposition in Liposomes Prepared by Brain Membrane-Like Lipid
• Mechanism of Neutral Liposome Membrane Fusion Induced by the Two Charge-Reversed Amphipathic Helical Peptides
• Synthesis of Mutants of a De Novo Designed Amyloid-forming Protein, Amyloidgenesin, and Their Amyloid-Forming Abilities
• A De Novo Designed α-to-β Transition Protein with an Amyloid Fibril Formation
• In vitro biophysical activities of newer all-synthetic surfactant composed of mixture of soybean PC or soybean PC-peptide
• Development of Low Cost Pulmonary Surfactant Composed of a Mixture of Lipids or Lipids-Peptide
• Introduction of both D-Amino Acids and Arg-Residues into Cationic Cytotoxic Peptides and Their Selectivity for Normal and Cancer Cells
• Substitution of Arg Residues for Lys Resudues in a Cationic Anti-Tumor Peptide Containing D-Amino Acids and Cytotoxicities
• Effect of Innovation of D-amino Acids into Novel Anti-Tumor Peptide and Protein on their Conformation and Cytotoxicities
• Synthesis of Transmembrane Segment Peptides and Its Analogs of A Single Spanning Protein, Isk, Forming Potassium Channel and Its Channel Formation Activity
• Studies on Association Behavior of Transmembrane Segment of Influenza Virus M2 Protein in Lipid Bilayers
• Theoretical Conformational Analysis of the Tandem Repeat Sequence in RNA Polymerase II
• Interaction of Tandem Repeat Sequence in RNA Polyemerase II with DNA
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water. III. A Comparison between Cationic Gemini/Cationic and Cationic Gemini/Nonionic Combinations
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water II: A Combination of Cationic Gemini-type Surfactant with MEGA-10
• Conformation Analysis of Proline Oligopeptides
• Conformational Analysis of Polypeptides Having Repetitive Ser-Pro Sequences
• Molecular Design of β-Hairpin Peptides Having RGDS Sequence for Tissue Engineering
• Conformational Analysis of Polypeptides Having Repetitive Xaa-Xaa-Xaa-Pro Sequences
• Roles of Counterion Binding in the Micelle Formation of Ionic Surfactants in Water
• Theoretical Analysis of β-Type Super-Secondary Structures Constructed by β-Strands
• Aggregation Behavior of Sodium Mono-n-Dodecyl Phosphate Surfactant in Aqueous Media, and Function in Catalytic Activity . I. Multi-Step Aggregates Formation and Catalytic Activity for Hydrolysis of p-Nitrophenyl Acetate in Aqueous Solution
• ASSOCIATION MODE OF A TRANSMEMBRANE α-HELICAL MODEL PEPTIDE, p24, AND ITS ANALOGS IN PHOSPHOPLIPID BILAYERS
• Evaluation of the Stability Constants for Alkaline-Earth Metal Complexes with Dodecaoxohexaphosphate(III) Using EDTA as a Complexation-Competing Agent
• A Review of Recent Studies on Aqueous Binary Mixed Surfactant Systems
• Conformational Analysis of Model Polypeptides Having Repetitive Ala-Ala-Pro Sequences
• Molecular Design of β-Hairpin Peptides Having Arg-Gly-Asp-Ser Sequence
• Conformational Analysis of Model Polypeptides Having Repetitive Xaa-Pro-Pro-Pro Sequences
• イオン性/非イオン性界面活性剤二成分混合系:相乗的に強められる界面活性および単分散組成(X2),ミセル組成(Y2)、ならびに気/水界面の吸着膜組成(Z3)の関係
• A Kinetic and Thermodynamic Study on Hydrolysis of Sodium Laurate in Aqueous Phase Accompanied by Transfer into Oil Phases Containing Different Organic Additives. (II)
• Antibacterial activity of amphipathic basic peptides with a long acyl group and their interaction with phospholipid bilayers.
• Transfer of homologous alkanols from water to fluorocarbon and hydrocarbon surfactant micelles.
• The sol-gel transition of sodium deoxycholate solutions under high pressures.
• The binding of sodium dodecyl sulfate to lysozyme in aqueous solutions. II. The effect of added NaCl.
• The effect of added NaCl on the binding of sodium perfluorooctanoate to lysozyme in aqueous solutions.
• A light-scattering study of temperature effect on micelle formation of N-alkanoyl-N-methylglucamines in aqueous solution.
• The binding of sodium dodecyl sulfate to lysozyme in aqueous solutions.
• Partial molal volumes of surfactants in methanol-water mixtures.
• The behavior of aqueous solution of sodium deoxycholate in capillary flow.

もっと見る 閉じる

スポンサーリンク