Design and Synthesis of Amphiphilic α-Helical Model Peptides with Various Hydrophobic-Hydrophilic Balances and Their Interaction with Lipid- and Biomembranes

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概要

• 論文の詳細を見る
• 1995-10-01

著者

• Sugihara Gohsuke

  Department of Chemistry, Faculty of Science, Fukuoka University

• LEE Sannamu

  Department of Chemistry, Faculty of Science, Fukuoka University

• KIYOTA Taira

  Department of Chemistry, Faculty of Science, Fukuoka University

• Sugihara Gohsuke

  Department Of Chem.istry Faculty Of Science Fukuoka University

• Kiyota Taira

  Department Of Chemistry Faculty Of Science Fukuoka University

• Lee S

  Department Of Chemistry Faculty Of Science Fukuoka University

• Lee Sannamu

  Department Of Chemistry Faculty Of Science Fukuoka University

関連論文

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• Effect of Hydrophobic Core Amino Acid Residues of P53 Oligomerization Domain on the Stability of Three-Dimensional Structure
• Study on Association Factor Using the Substituted Analogs of Tetramerization Domain of Tumor Suppressor Protein p53
• Micelle Formation of Phosphate-Type Hybrid Surfactants in Aqueous Solution
• Synthesis of Second Transmembrane Segment Peptides in Band 3 Protein from Human Erythrocyte Membrane and Their Interaction with Model Membranes
• Interaction if the Fragments Characteristic of Bactenecin 7 with Phospholipid Bilagyers and Their Antimicrobial Activity
• Amyloid Formation and Cytotoxicity of a De Novo Designed Protein, Amyloidgenesin, and Its Analogs
• Structure and Bilogical Activity of the Neuropeptide γ
• Purification and Characterization of a Novel Antimicrobial Peptide from the Skin of Hagfish, Eptatretus Burgeri.
• Secondary Structures of Synthetic Peptides Corresponding to the First Membrane-Contact Portion of Normal Band 3 and Its Deletion Mutant (Southeast Asian Ovalocytosis)
• Nanotubular Structure Formation by a De Novo-designed Amphiphilic α-Helical Peptide, Hel 13-5, and Various Biomembrane-specific Lipids
• The Effect of D-Amino Acid-Containing Basic Peptides with Different Hydrophobicity on the Antimicrobial and Cytotoxic Activity
• FIBRIL STRUCTURE FORMED BY THE INTERACTION OF AN AMPHIPHILIC α-HELICAL PEPTIDE, HEL 13-5, AND ITS ANALOGS WITH PHOSPHOLIPIDS
• INTERACTION OF AMYLOID β-PEPTIDE (1-40) WITH A LIPID-MIXTURE HAVING BRAIN MEMBRANE-LIKE LIPID COMPOSITION
• 各種胆汁酸から合成したカチオン活性剤のミセル形成に関する熱力学的研究
• Synthesis of Mutants of Lipophilic Core in a De Novo Designed Small Globular Protein (SGP) and Their Interactions with Lipid-and Bio-Membranes
• Structure and Activity Relationship of D-Amino Acid Incorporated Antimicrobial Model Peptides
• Morphological Change of Acidic and Neutral Liposomes Induced by Basic Amphiphilic α-Helical Pepties with Systematically Varied Hydrophobic Hydrophilic Balance
• N- and C-Terminal Effect of Amphiphilic α-Helical Peptides on the Interaction with Model- and Bio-Membranes
• Effect of Amphiphilic α-Helical Model Peptides with Systematically Varied Hydrophobic-Hydrophilic Balance on the Interaction with the Lipid Bilayers
• De Novo Design, Synthesis and Characterization of Three Analogs Related to a Pore-Forming Small Globular Protein (SGP)
• Effect of N- and C-Termini Blocked and Both-Terminal Free Amphiphilic Peptides on Interaction with Model- and Bio-Membranes
• Translocation of a Mimic Little Super Protein (LSP) from Aqueous Solution into Lipid Bilayers
• De Novo Synthesis of a Little Super Protein (LSP) with a Hydrophobic Helix Surrounded by Three Basic Amphiphilic Helices and Its Solution Property
• Interaction of Mastoparan B and Its Ala-Substituted Analogs with Phospholipid Bilayers
• Design and Synthesis of Amphiphilic α-Helical Model Peptides with Various Hydrophobic-Hydrophilic Balances and Their Interaction with Lipid- and Biomembranes
• Structure-Activity Relationships of Tachykinin Peptides Derived from Fish
• The Effect of Peptide Chain Length on the Nanotubular Structure Formed by the Interaction of an Amphiphilic α-Helical Peptide, Hel 13-5, with Phospholipid
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• Transport Behavior of Lipids Solubilized by Bile Salts across Porous Membranes
• Design and Synthesis of an Oxidation-Responsible Amyloid Fibril Formation Protein, AG-Met
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water. IV. Three Combinations of SDS with MEGA-8, -9 and -10
• Nanotubule Formed by a Hydrophobic Amphiphilic α-Helical Peptide and Natural Phospholipids and Its Application
• Effect of Cholesterol on Amyloid Beta-Peptide Deposition in Liposomes Prepared by Brain Membrane-Like Lipid
• Mechanism of Neutral Liposome Membrane Fusion Induced by the Two Charge-Reversed Amphipathic Helical Peptides
• Synthesis of Mutants of a De Novo Designed Amyloid-forming Protein, Amyloidgenesin, and Their Amyloid-Forming Abilities
• A De Novo Designed α-to-β Transition Protein with an Amyloid Fibril Formation
• In vitro biophysical activities of newer all-synthetic surfactant composed of mixture of soybean PC or soybean PC-peptide
• Development of Low Cost Pulmonary Surfactant Composed of a Mixture of Lipids or Lipids-Peptide
• Introduction of both D-Amino Acids and Arg-Residues into Cationic Cytotoxic Peptides and Their Selectivity for Normal and Cancer Cells
• Substitution of Arg Residues for Lys Resudues in a Cationic Anti-Tumor Peptide Containing D-Amino Acids and Cytotoxicities
• Effect of Innovation of D-amino Acids into Novel Anti-Tumor Peptide and Protein on their Conformation and Cytotoxicities
• Synthesis of Transmembrane Segment Peptides and Its Analogs of A Single Spanning Protein, Isk, Forming Potassium Channel and Its Channel Formation Activity
• Studies on Association Behavior of Transmembrane Segment of Influenza Virus M2 Protein in Lipid Bilayers
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water. III. A Comparison between Cationic Gemini/Cationic and Cationic Gemini/Nonionic Combinations
• Adsorption and Micelle Formation of Mixed Surfactant Systems in Water II: A Combination of Cationic Gemini-type Surfactant with MEGA-10
• Roles of Counterion Binding in the Micelle Formation of Ionic Surfactants in Water
• Aggregation Behavior of Sodium Mono-n-Dodecyl Phosphate Surfactant in Aqueous Media, and Function in Catalytic Activity . I. Multi-Step Aggregates Formation and Catalytic Activity for Hydrolysis of p-Nitrophenyl Acetate in Aqueous Solution
• ASSOCIATION MODE OF A TRANSMEMBRANE α-HELICAL MODEL PEPTIDE, p24, AND ITS ANALOGS IN PHOSPHOPLIPID BILAYERS
• Evaluation of the Stability Constants for Alkaline-Earth Metal Complexes with Dodecaoxohexaphosphate(III) Using EDTA as a Complexation-Competing Agent
• A Review of Recent Studies on Aqueous Binary Mixed Surfactant Systems
• イオン性/非イオン性界面活性剤二成分混合系:相乗的に強められる界面活性および単分散組成(X2),ミセル組成(Y2)、ならびに気/水界面の吸着膜組成(Z3)の関係
• The Effect of Ion on the Stability of Three Dimensional Structure of Tumor Suppressor Protein, p53, Oligomerization Domain in Solution
• A Kinetic and Thermodynamic Study on Hydrolysis of Sodium Laurate in Aqueous Phase Accompanied by Transfer into Oil Phases Containing Different Organic Additives. (II)
• Antibacterial activity of amphipathic basic peptides with a long acyl group and their interaction with phospholipid bilayers.
• Transfer of homologous alkanols from water to fluorocarbon and hydrocarbon surfactant micelles.
• The sol-gel transition of sodium deoxycholate solutions under high pressures.
• The binding of sodium dodecyl sulfate to lysozyme in aqueous solutions. II. The effect of added NaCl.
• The effect of added NaCl on the binding of sodium perfluorooctanoate to lysozyme in aqueous solutions.
• A light-scattering study of temperature effect on micelle formation of N-alkanoyl-N-methylglucamines in aqueous solution.
• The binding of sodium dodecyl sulfate to lysozyme in aqueous solutions.
• Partial molal volumes of surfactants in methanol-water mixtures.
• The behavior of aqueous solution of sodium deoxycholate in capillary flow.
• A pH and pNa study of aqueous solutions of sodium deoxycholate.
• Secondary Structures of Synthetic Peptides Corresponding to the First Membrane-Contact Portion of Normal Band 3 and Its Deletion Mutant (Southeast Asian Ovalocytosis).

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