Type of Electrical Stimulation Influences Diaphragm Response to Adrenoceptor and Calcium Channel Modulators : the Role of Extracellular and Intracellular Calcium Events
スポンサーリンク
概要
- 論文の詳細を見る
The influence of direct single pulse and subtetanic electrical stimulation (ES) on isolated rat hemidiaphragm response to adrenoceptor antagonists and calcium channel blockers was investigated. Muscle contractility was stimulated by cumulative micromolar noradrenaline. Noradrenaline effects on developed tension (Td) in the presence of various α- and β-adrenoceptor antagonists (e.g., prazosin and ICI 118551) were qualitatively different during different types of ES. Also, intact L-voltage calcium channels were necessary for noradrenaline-induced potentiation of Td during both types of ES, while the balance between ryanodine receptors- and inositol triphosphate (IP3)-related calcium events in the muscle was influenced by the pattern of the ES.
- 社団法人 日本薬理学会の論文
- 2006-11-20
著者
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Stojanovic Radan
Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of
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Todorovic Zoran
Inst. For Pharmacology Clinical Pharmacology And Toxiciology Fac. Of Medicine Univ. Of Belgrade Serb
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Todorovic Zoran
Department Of Pharmacology Clinical Pharmacology And Toxicology School Of Medicine University Of Bel
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Stojanovic Radan
Department Of Pharmacology Clinical Pharmacology And Toxicology School Of Medicine University Of Bel
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PROSTRAN Milica
Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of
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NESIC Zorica
Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of
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DIVAC Nevena
Department of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine, University of
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VOJVODIC Nikola
Institute of Neurology, School of Medicine, University of Belgrade
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CEROVAC-COSIC Natasa
Clinic for Child Neurology and Psychiatry, Medical Faculty, University of Belgrade
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Prostran Milica
Inst. For Pharmacology Clinical Pharmacology And Toxiciology Fac. Of Medicine Univ. Of Belgrade Serb
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Prostran Milica
Department Of Pharmacology Clinical Pharmacology And Toxicology School Of Medicine University Of Bel
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Prostran Milica
Department Of Pharmacology Clinical Pharmacology And Toxicology Faculty Of Medicine University Of Be
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Vojvodic Nikola
Institute Of Neurology School Of Medicine University Of Belgrade
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Nesic Zorica
Department Of Pharmacology Clinical Pharmacology And Toxicology School Of Medicine University Of Bel
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Divac Nevena
Department Of Pharmacology Clinical Pharmacology And Toxicology School Of Medicine University Of Bel
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Cerovac-cosic Natasa
Clinic For Child Neurology And Psychiatry Medical Faculty University Of Belgrade
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Todorovic Zoran
Department Of Pharmacology Clinical Pharmacology And Toxicology Faculty Of Medicine University Of Be
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Todorovic Zoran
Department of Clinical Pharmacology, Pharmacology and Toxicology, School of Medicine University of Belgrade
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Nesic Zorica
Department of Clinical Pharmacology, Pharmacology and Toxicology, School of Medicine University of Belgrade
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Stojanovic Radan
Department of Clinical Pharmacology, Pharmacology and Toxicology, School of Medicine University of Belgrade
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Prostran Milica
Department of Clinical Pharmacology, Pharmacology and Toxicology, School of Medicine University of Belgrade
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