An Anti-Estrogenic Lignan Glycoside, Tracheloside, from Seeds of Carthamus tinctorius

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概要

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• The lignan glycoside, tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method. Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC50 value of 0.31 μg/ml, a level of inhibition comparable to that of tamoxifen (IC50 = 0.43 μg/ml).

• 社団法人 日本農芸化学会の論文
• 2006-11-23

著者

• Park Jeong

  Res. Inst. Of Pharmaceutical Sciences Coll. Of Pharmacy Seoul National Univ.

• PARK Jeong

  College of Pharmacy, Seoul National University

• YOO Hye

  College of Pharmacy, Seoul National University

• Park Jeong

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sciences Seoul National Univ.

• Yoo Hye

  College Of Pharmacy And Research Institute Of Pharmaceutical Sciences Seoul National University

• Yoo Hye

  College Of Pharmacy Seoul National University

• Park Jeong

  College Of Pharmacy And Research Institute Of Pharmaceutical Sciences Seoul National University

• Kwon Sung

  Coll. Of Pharmacy And Res. Inst. Of Pharmaceutical Sciences Seoul National Univ.

• Kwon Sung

  College Of Pharmacy And Research Institute Of Pharmaceutical Sciences Seoul National University

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