非アルコール性脂肪性肝疾患におけるエラストメーターの臨床的有用性

概要

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This study was conducted to elucidate the efficacy of elastometry in patients with nonalcoholic fatty liver disease. A total of 45 patients (4 simple steatosis and 41 nonalcoholic steatohepatitis (NASH)) and 22 healthy controls were enrolled in this study. Liver stiffness was measured by elastography or FibroScan502 (Echosens Co., Paris, France). Whereas significant differences of elastometry were not seen between patients with simple steatosis and healthy controls, those were evident between patients with simple steatosis and NASH. Furthermore, the elastometry correlated well to the stage of fibrosis in patients with NASH. These results suggest that elastometry would be useful for discriminating NASH from simple steatosis and evaluating fibrotic staging of the liver without any invasiveness.
2006-09-25