Enhancement Effects and Relaxivities of Gadolinium-DTPA at 1.5 versus 3 Tesla : A Phantom Study
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概要
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Purpose: To investigate the difference in enhancement effects and relaxivities of the gadolinium chelate at 1.5 and 3 Tesla (T) and to elucidate the contribution of the high magnetic field to contrast enhancement in spin-echo (SE) and gradient-echo (GRE) images. Methods: Phantoms containing water with or without gadopentetate dimeglumine (Gd-DTPA) at different concentrations were scanned using 1.5T and 3T MRI scanners of the same manufacturer and under the same temperature conditions and scanning parameters. Relaxivities of gadolinium, R1 and R2, were estimated from serial T1 and T2 values of the phantoms using linear regression. Contrast enhancement ratios in SE and GRE T1-weighted images were compared at 1.5 and 3T. Results: The R1 and R2 of Gd-DTPA at 1.5 and 3T were 4.79 and 5.14, and 4.50 and 5.09, respectively. Although the relaxivities at 3T were slightly lower than those at 1.5T, the contrast enhancement ratio improved in both SE and GRE images as a result of T1 prolongation of the water at 3T. Conclusion: The decrease in relaxivities of the Gd-DTPA at 3T appears to be so small that T1 prolongation of the water improves contrast enhancement, suggesting a potential clinical advantage in administration of Gd-DTPA at high field strength.
- 日本磁気共鳴医学会の論文
- 2005-11-15
著者
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SASAKI Makoto
Department of Radiology, Iwate Medical University
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Sasaki Makoto
Department Of Radiology Iwate Medical University
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KANBARA Yoshiyuki
Memorial Heart Center, Iwate Medical University
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SHIBATA Eri
Advanced Medical Research Center, Iwate Medical University
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SHIBATA Eri
Department of Radiology, Iwate Medical University
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EHARA Shigeru
Department of Radiology, Iwate Medical University
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KANBARA Yoshiyuki
High Field Magnetic Resonance Imaging Research Institute, Iwate Medical University, School of Medici
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Ehara Shigeru
Department Of Radiology Iwate Medical University
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Sasaki Makoto
Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie
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Shibata Eri
Advanced Medical Research Center Iwate Medical University
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Shibata Eri
Department Of Pharmacy Kinki Central Hospital
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Shibata Eri
Department Of Radiology Iwate Medical University School Of Medicine
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Sasaki Makoto
Departments Of Neurosurgery Iwate Medical University School Of Medicine
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Kanbara Yoshiyuki
Memorial Heart Center Iwate Medical University
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Sasaki Makoto
Department Of Biochemistry Ii Nagoya City University Medical School
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Sasaki Makoto
Deparment Of Mathematical System Science Faculty Of Science And Technology Hirosaki University
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Sasaki Makoto
Department Of Radiology Iwate Medical University School Of Medicine
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