Effects of Hair Treatment on Hair Mercury-The Best Biomarker of Methylmercury Exposure?
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概要
- 論文の詳細を見る
Objectives: Exposure misclassification is a major obstacle to obtain accurate dose-response relationships. In order to solve this problem, the impact of hair treatment on total mercury in hair was assessed in Japanese women. Methods: A cross-sectional study was carried out among 327 women at age 24-49 years to determine hair mercury levels and estimate daily mercury intakes from seafood by using a food frequency questionnaire. Results: Hair mercury levels in the women and daily mercury intake ranged from 0.11 to 6.86 (median 1.63) μg/g and from 0.77 to 144.9 (median 15.0) μg/day, respectively. The hair mercury was positively correlated with the daily mercury intake (p<0.001). When the women were divided into two subgroups based on artificial hair-waving, hair coloring/dyeing, residence (non-fishing and fishing areas), and working status, a significant difference in the hair mercury level was observed between the women with and without artificial hair-waving only (p<0.001). The multiple regression analysis showed that the log-transformed hair mercury level was significantly related to the log-transformed daily mercury intake (standardized regression coefficient βs=0.307) and artificial hair-waving (βs=−0.276); but not to hair coloring/dyeing, residence, working status or age. Permanent hair treatment was estimated to reduce total mercury in hair by approximately 30%, after adjusting for daily mercury intake and other possible factors. Conclusions: These findings suggest that hair mercury is not the best biomarker of methylmercury exposure when a study population includes women with artificial hair-waving.
- 日本衛生学会の論文
- 2005-07-01
著者
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Satoh Hiroshi
Department of Pharmacy, Niigata University Medical and Dental Hospital
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Liu Xiao-jie
State Key Laboratory Of Environmental Geochemistry Institute Of Geochemistry Chinese Academy Of Scie
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Suzuki Keita
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Suzuki Keita
Department Of Nanochemistry Faculty Of Engineering Tokyo Polytechnic University
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Suzuki Maki
東北大学 医系研究 障害科学 専攻 高次機能障害学 分野
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Nakai Kunihiko
Department of Environmental Health Sciences, Tohoku University Graduate School of Medicine
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SAKAMOTO Mineshi
Department of Epidemiology, National Institute for Minamata Disease
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IWATA Toyoto
Department of Environmental Health Sciences, Akita University School of Medicine
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MURATA Katsuyuki
Department of Environmental Health Sciences, Akita University School of Medicine
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DAKEISHI Miwako
Department of Environmental Health Sciences, Akita University School of Medicine
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LIU Xiao-Jie
Department of Epidemiology, National Institute for Minamata Disease
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OHNO Tomoko
Department of Environmental Health Sciences, Akita University School of Medicine
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KUROSAWA Tomoko
Department of Environmental Health Sciences, Akita University School of Medicine
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Oka Tomoko
Department Of Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Iwata Toyoto
Department Of Environmental Health Sciences Akita University School Of Medicine
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Nakai K
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Nakai Kunihiko
Department Of Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Dakeishi Miwako
Department Of Dermatology Akita University School Of Medicine
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Satoh Masahiko
Department Of Hygienics Gifu Pharmaceutical University
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Kurosawa Tomoko
Department Of Environmental Health Sciences Akita University School Of Medicine
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Sakamoto Mineshi
Department Of Epidemiology National Institute For Minamata Disease
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Ohno Tomoko
Department Of Chemical Analysis Pharmaceutical Research Laboratories Dainippon Pharmaceutical Co. Lt
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Satoh H
Tohoku Univ. Graduate School Of Medicine Sendai
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Satoh Hiroshi
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Murata Katsuyuki
秋田大学 医学部医学科社会環境医学
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Murata Katsuyuki
Department Of Environmental Health Sciences Akita University Graduate School Of Medicine
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Satoh H
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Satoh Hiroshi
Department Of Biology Faculty Of Science Shizuoka University
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Satoh Hiroshi
Tohoku University Graduate School Of Medicine
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Suzuki Keita
Department Of Applied Chemistry Nagoya Institute Of Technology
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