Factors Affecting Hand Tremor and Postural Sway in Children
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概要
- 論文の詳細を見る
Objectives : It is crucial to consider covariates relevant for outcome variables in developing doseeffect relations of environmental hazardous toxins. The aim of this study was to clarify the covariates affecting hand tremor and postural sway in children. Methods : Hand tremor and postural sway, as well as hair mercury concentrations, were measured in 155 boys and 148 girls at age 7 years. Results : Current mercury concentrations in child hair ranged from 0.35 to 6.32 μg/g (geometric mean, 1.71 μg/g for boys and 1.58 μg/g for girls), and were not significantly correlated with the neuromotor parameters. All hand tremor and postural sway parameters, except for tremor intensity at 1-6 Hz with non-dominant hand, were significantly larger in the boys than in the girls. Using multiple regression analysis, some postural sway parameters were related negatively to age in the boys and girls (p<0.05), and positively to height (p<0.05). Similarly, hand tremor parameters were positively related to age, height and heart rate either in the boys or in the girls (p<0.05). Also, there were positive relationships between tremor intensity at 1-6 Hz and transversal and sagittal sways at 1-2 Hz and 2-4 Hz (p<0.05). Conclusions : Heart rate and postural sway, together with age, sex, and height, should be considered in interpreting hand tremor in children. Hand tremor or postural sway may not be so sensitive or specific to methylmercury exposures at levels of less than 7 μg/g in hair.
- 日本衛生学会の論文
著者
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Satoh Hiroshi
Department of Pharmacy, Niigata University Medical and Dental Hospital
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Nakai Kunihiko
Department of Environmental Health Sciences, Tohoku University Graduate School of Medicine
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SAKAMOTO Mineshi
Department of Epidemiology, National Institute for Minamata Disease
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IWATA Toyoto
Department of Environmental Health Sciences, Akita University School of Medicine
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MURATA Katsuyuki
Department of Environmental Health Sciences, Akita University School of Medicine
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DAKEISHI Miwako
Department of Environmental Health Sciences, Akita University School of Medicine
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Iwata Toyoto
Department Of Environmental Health Sciences Akita University School Of Medicine
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Nakai K
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Nakai Kunihiko
Department Of Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Dakeishi Miwako
Department Of Dermatology Akita University School Of Medicine
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Satoh Masahiko
Department Of Hygienics Gifu Pharmaceutical University
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Sakamoto Mineshi
Department Of Epidemiology National Institute For Minamata Disease
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Satoh H
Tohoku Univ. Graduate School Of Medicine Sendai
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Satoh Hiroshi
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Murata Katsuyuki
秋田大学 医学部医学科社会環境医学
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Murata Katsuyuki
Department Of Environmental Health Sciences Akita University Graduate School Of Medicine
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Satoh H
Environmental Health Sciences Tohoku University Graduate School Of Medicine
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Satoh Hiroshi
Department Of Biology Faculty Of Science Shizuoka University
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Satoh Hiroshi
Tohoku University Graduate School Of Medicine
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