High Molecular Weight Form Insulin-like Growth Factor II-producing Mesenteric Sarcoma Causing Hypoglycemia
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概要
- 論文の詳細を見る
An 81-year-old woman presented with frequent episodes of hypoglycemia. Her serum level of insulin was normal, but her serum insulin-like growth factor (IGF)-II level was high. She was found to have a spindle cell sarcoma originated from the mesentery of the sigmoid colon, which was completely resected. Postoperatively, hypoglycemia ameliorated with concomitant reduction in serum IGF-II levels. Immunohistochemical study revealed positive immunostaining for IGF-II in tumor cells, and the abundant expression of IGF-II mRNA was demonstrated by RT-PCR. The presence of high molecular weight (HMW) form IGF-II in patients serum was confirmed by immunoblotting. This is the first report of a patient with HMW form IGF-II-producing mesenteric sarcoma causing hypoglycemia.
- 社団法人 日本内科学会の論文
- 2004-10-01
著者
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Hizuka Naomi
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Womens Medical University
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Aiba Motohiko
Department Of Pathology School Of Medicne Keio University
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Hitara Yukio
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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Hizuka Naomi
Department Of Medicine And Gastroenterology Tokyo Women's Medical University
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SATO Ryuji
Division of Cardiology, Department of Medicine, Showa University School of Medicine
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Sato Ryuji
Division Of Cardiology Department Of Medicine Showa University School Of Medicine
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SHICHIRI Masayoshi
Department of Clinical and Molecular Endocrinology, Graduate School, Tokyo Medical and Dental Univer
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Shichiri Masayoshi
Department Of Clinical And Molecular Endocrinology Tokyo Medical And Dental University Graduate Scho
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Shichiri Masayoshi
Department Of Clinical And Molecular Endocrinology Graduate School Tokyo Medical And Dental Universi
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Aiba Motohiko
Department Of Surgical Pathology Tokyo Women's Medical University Daini Hospital
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Aiba Motohiko
Department Of Pathology School Of Medicine Keio University
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TSUJINO Motoyoshi
Division of Internal Medicine and Surgery, Tokyo Metropolitan Fuchu Hospital
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NISHIDA Kenji
Division of Internal Medicine and Surgery, Tokyo Metropolitan Fuchu Hospital
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OTANI Yasukazu
Division of Internal Medicine and Surgery, Tokyo Metropolitan Fuchu Hospital
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MINAMI Tomohito
Division of Internal Medicine and Surgery, Tokyo Metropolitan Fuchu Hospital
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Tsujino Motoyoshi
Division Of Internal Medicine And Surgery Tokyo Metropolitan Fuchu Hospital
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Otani Yasukazu
Division Of Internal Medicine And Surgery Tokyo Metropolitan Fuchu Hospital
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Minami Tomohito
Division Of Internal Medicine And Surgery Tokyo Metropolitan Fuchu Hospital
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Sato Ryuji
Division Of Internal Medicine And Surgery Tokyo Metropolitan Fuchu Hospital
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Nishida Kenji
Division Of Internal Medicine And Surgery Tokyo Metropolitan Fuchu Hospital
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Shichiri Masayoshi
Department Of Clinical And Molecualr Endocrinology Tokyo Medicine And Dental University Graduate School
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HIZUKA NAOMI
Department of Internal Medicine Tokyo Women's Medical College
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