Acquired Factor V Inhibitor Responsive to Corticosteroids in a Patient with Double Cancers
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概要
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A 70-year-old woman suffering from HCV-related liver cirrhosis was admitted for abnormal bleeding. Laboratory findings included PT at 46.6 sec, APTT at >212 sec, factor V activity of <3%, and factor V inhibitor of 2 BU. Having experienced a persistent bleeding tendency for one month, the patient was started on prednisolone (0.8 mg/kg/day). Within a few days, the inhibitor became undetectable and clinical bleeding disappeared. Although clinical improvement was achieved, she died 6 months after the initial bleeding episode from the progression of a lung cancer. An autopsy revealed squamous cell carcinoma of the lung and hepatocellular carcinoma.
- 社団法人 日本内科学会の論文
著者
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Aiba Motohiko
Department Of Pathology School Of Medicine Keio University
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Iga Daijiro
Department Of Medicine Tokyo Women's Medical University Daini Hospital
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Otsuka Kuniaki
Department Of Anesthesiology Tokyo Women's Medical University Second Hospital
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Ogasawara Toshie
Department Of Medicine Tokyo Women's Medical University Daini Hospital
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Tomimatsu Masahiko
Department Of Medicine Tokyo Women's Medical University Daini Hospital
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Endo Hitoshi
Department Of Biochemical Engineering Graduate School Of Science And Technology Yamagata University
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Kawauchi Kiyotaka
Department Of Medicine Tokyo Women's Medical University Daini Hospital
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Yasuyama Masako
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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Saito Toshihito
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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Iga Daijiro
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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Tomimatsu Masahiko
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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Endo Hitoshi
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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Ogasawara Toshie
Department of Internal Medicine, Tokyo Women's Medical University Medical Center East
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