Renin, Cyclooxygenase-2 and Neuronal Nitric Oxide Synthase in the Kidneys of Transgenic Tsukuba Hypertensive Mouse
スポンサーリンク
概要
- 論文の詳細を見る
The transgenic Tsukuba hypertensive mouse (THM), which expresses the human renin and angiotensinogen genes, develops hypertension secondary to increased renin-angiotensin system activity. The aim of the present study was to assess expression of the renin, cyclooxygenase-2 (COX-2), and neuronal nitric oxide synthase (nNOS) proteins in THM kidneys by immunohistochemical stainings. Renin expression was decreased in the THM kidneys when compared to kidneys from heterozygotes or control mice. Although no differences were observed in nNOS expression, overexpression of the COX-2 protein was observed in the macula densa cells in THM kidneys.
- 社団法人 日本実験動物学会の論文
著者
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松元 光春
鹿児島大学農学部家畜解剖学教室
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松元 光春
鹿大・農・獣医
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松本 光春
鹿児島大学 農学部 家畜内科学 教室
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YABUKI Akira
Department of Veterinary Anatomy, Faculty of Agriculture, Kagoshima University
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SUZUKI Syusaku
Department of Veterinary Anatomy, Faculty of Agriculture, Kagoshima University
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TANIGUCHI Kazuyuki
Laboratory of Veterinary Anatomy, Iwate University
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Taniguchi K
Dep. Of Veterinary Anatomy School Of Veterinary Medicine And Animal Sciences Kitasato Univ.
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Taniguchi K
Steelmaking Research Section Iron And Steel Research Laboratories Kobe Steel Ltd.
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Tsuchiya K
Laboratory Of Paramedical Sciences Department Of Veterinary Medicine Faculty Of Agriculture Iwate Un
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Yabuki A
中華人民共和国
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Yabuki Akira
Department Of Electrical Engineering And Information Science Yamagata University
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Suzuki S
Laboratory Of Veterinary Anatomy Faculty Of Agriculture Kagoshima University
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Suzuki Shusaku
Lab. Of Veterinary Anatomy Dep. Of Veterinary Medicine
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Kamimura R
Frontier Science Research Center Kagoshima University
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Kamimura Ryozo
Divison Of Laboratory Animal Science Research Center For Life Science Resources Kagoshima University
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Suzuki S
Department Of Veterinary Medicine Faculty Of Agriculture Kagoshima University
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MATSUMOTO Mitsuharu
Department of Veterinary Anatomy, Faculty of Agriculture, Kagoshima University
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Matsumoto M
Department Of Veterinary Anatomy Faculty Of Agriculture Kagoshima University
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Kamimura Ryouzou
Frontier Science Research Center Kagoshima University
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Suzuki Syusaku
Laboratory Of Veterinary Anatomy Department Of Veterinary Medicine Faculty Of Agriculture Kagoshima
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Taniguchi Kazuyuki
Laboratory Of Veterinary Anatomy Iwate University
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Suzuki Syusaku
Department Of Veterinary Anatomy Faculty Of Agriculture Kagoshima University
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MATSUMOTO Mitsuharu
Department of Basic Veterinary Science, Faculty of Agriculture, Kagoshima University
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YABUKI Akira
Department of Clinical Veterinary Science, Faculty of Agriculture, Kagoshima University
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Taniguchi Kazuyuki
Laboratory of Paramedical Sciences, Department of Veterinary Medicine, Iwate University
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