検疫中に下痢を認めた中国由来カニクイザルの臨床学的諸数値
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概要
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Shin Nippon Biomedical Laboratories, Ltd. (SNBL) imported and quarantined 3,148 cynomolgus monkeys (aged 2.5 to 6.5 years) from China in 2002. The hematology and blood biochemistry data obtained from these monkeys on Day 32 of quarantine were analyzed separately by sex [2,890 animals in which no abnormalities were observed during the 35-day quarantine period (normal group), and 258 animals which exhibited diarrhea 1 to 12 times (diarrhea group)]. The values obtained for all parameters were within the normal range (mean ± SD), and no significant abnormalities were noted in either sex. The clinical pathology data from 11 animals (6 males and 5 females) exhibiting diarrhea repeatedly (10 to 12 times) were statistically analyzed, and significant differences were noted in PLT and ALP in both sexes. The PLT values of these animals were within the normal group mean ± 2 SD, and were considered within the normal range. A significant difference was noted in some individual ALP values (males: Nos. 2 and 3, females: Nos. 1, 3, and 4). The clinical pathology data obtained from the normal group in this study basically correspond to the widely reported results already obtained from healthy cynomolgus monkeys, from which it can be concluded that the cynomolgus monkeys from China were generally healthy and presenting no particular abnormality. The clinical pathology data from the normal group will serve as valuable baseline data for experimenters using cynomolgus monkeys.
- 社団法人 日本実験動物学会の論文
著者
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TOKADO Hiroshi
Shin Nippon Biomedical Laboratories (SNBL), Ltd.
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FUKUZAKI Koichiro
Shin Nippon Biomedical Laboratories (SNBL), Ltd.
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LIU Yan-Wei
Department of Electronic Engineering, National Taiwan University of Science and Technology
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SUZUKI Syusaku
Department of Veterinary Anatomy, Faculty of Agriculture, Kagoshima University
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鈴木 秀作
鹿児島大学 農学部家畜解剖学教室
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鈴木 秀作
鹿児島大学農学部
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Miyajima Hiroaki
Shin Nippon Biomedical Laboratories, Ltd., Japan
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劉 艶薇
鹿児島大学農学部
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Tokado Hiroshi
Shin Nippon Biomedical Laboratories (snbl) Ltd.
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加島 政利
株式会社新日本科学
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劉 艶薇
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
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鈴木 秀作
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
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加島 政利
Shin Nippon Biomedical Laboratories Ltd.
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KASHIMA Masatoshi
Shin Nippon Biochemical Laboratories, Ltd.
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Miyajima Hiroaki
Shin Nippon Biochemical Laboratories Ltd.
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Miyajima Hiroaki
Shin Nippon Biomedical Laboratories Ltd.
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Fukuzaki Koichiro
Shin Nippon Biomedical Laboratories (snbl) Ltd.
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Fukuzaki Koichiro
Shin Nippon Biomedical Laboratories Ltd.
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Liu Yan-wei
Department Of Electronic Engineering National Taiwan University Of Science And Technology
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Kashima Masatoshi
Shin Nippon Biochemical Laboratories Ltd.
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Suzuki Syusaku
Department Of Veterinary Anatomy Faculty Of Agriculture Kagoshima University
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LIU Yan-Wei
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
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SUZUKI Syusaku
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University
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KASHIMA Masatoshi
Shin Nippon Biomedical Laboratories Ltd.
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TOKADO Hiroshi
Shin Nippon Biomedical Laboratories Ltd.
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