MOLECULAR BIOLOGY OF THE VHL GENE

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概要

• 論文の詳細を見る

著者

• HINO Okio

  Department of Experimental Pathology, Cancer Institute

• Hino Okio

  Department Of Experimental Pathology Cancer Institute

• TSUCHIYA Haruo

  Department of Experimental Pathology, Cancer Institute

• SATAKE Nobuo

  Department of Experimental Pathology, Cancer Institute

• Satake Nobuo

  Department Of Experimental Pathology Cancer Institute

• Tsuchiya Haruo

  Department Of Experimental Pathology Cancer Institute

• MAHER Eamonn

  Division of Medical Genetics, Department of Paediatrics and Child Health, University of Birmingham,

• Maher Eamonn

  Division Of Medical Genetics Department Of Paediatrics And Child Health University Of Birmingham Bir

• Satake Nobuo

  Department Of Diagnostic Pathology Tokushima Prefectural Central Hospital

関連論文

• Serum level of expressed in renal carcinoma (ERC)/ mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT)
• Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis
• A Novel "Nihon" Rat Model of a Mendelian Dominantly Inherited Renal Cell Carcinoma
• Malignant perivascular epithelioid cell tumor of the colon : Report of a case with molecular analysis
• RENAL CARCINOGENESIS : GENOTYPE, PHENOTYPE AND DRAMATYPE
• Renal carcinogenesis : Genotype, phenotype and dramatype
• Intragenic Tsc2 Somatic Mutations as Knudson's Second Hit in Spontaneous and Chemically Induced Renal Carcinomas in the Eker Rat Model
• PATHOPHYSIOLOGICAL FEATURES OF HEREDITARY CANCERS
• Cloning of the Rat Homologue of the von Hippel-Lindau Tumor Suppressor Gene and Its Non-somatic Mutation in Rat Renal Cell Carcinomas
• Allelic Loss at the Tuberous Sclerosis (Tsc2) Gene Locus in Spontaneous Uterine Leiomyosarcomas and Pituitary Adenomas in the Eker Rat Model
• Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo
• Establishment of a novel specific ELISA system for rat N- and C-ERC/mesothelin. Rat ERC/mesothelin in the body fluids of mice bearing mesothelioma
• Novel ELISA system for detection of N-ERC/mesothelin in the sera of mesothelioma patients
• A Novel Gene"Niban "Upregulated in Renal Carcinogenesis: Cloning by the cDNA-amplified Fragment Length Polymorphism Approach
• Toward chemotherapy for Tsc2-mutant renal tumor
• Generation of Metastatic Variants of Eker Renal Carcinoma Cell Lines for Experimental Investigation of Renal Cancer Metastasis
• Age dependence of radiation-induced renal cell carcinomas in an Eker rat model
• A Novel Renal Carcinoma Predisposing Gene of the Nihon Rat Maps on Chromosome 10
• HZE Radiation Effects for Hereditary Renal Carcinomas
• Pathogenesis of multifocal micronodular pneumocyte hyperplasia and lymphangioleiomyomatosis in tuberous sclerosis and association with tuberous sclerosis genes TSC1 and TSC2
• Development of High-grade Renal Cell Carcinomas in Rats Independently of Somatic Mutations in the Tsc2 and VHL Tumor Suppressor Genes
• Knudson’s two hits, both associated with the insertions of genetic mobile elements in a rat pituitary adenoma
• JTII-1 A case of mesothelioma in which cytology was useful for the diagnosis
• CARCINOGENESIS IN TUBEROUS SCLEROSIS
• Diagnostic tumor marker of asbestos-related mesothelioma
• Hepatoprotective Drugs for the Treatment of Virus-Induced Chronic Hepatitis: From Hypercarcinogenic State to Hypocarcinogenic State
• Understanding the hypercarcinogenic state in chronic hepatitis: a clue to the prevention of human hepatocellular carcinoma
• Analysis of the initial gene in radiation induced tumors
• Down-regulation of cyclooxygenase-2 expression but up-regulation of cyclooxygenase-1 in renal carcinomas of the Eker (TSC2 gene mutant) rat model
• MOLECULAR BIOLOGY OF THE VHL GENE
• Molecular tumor markers for asbestos-related mesothelioma : Serum diagnostic markers
• Studies of familial tumors using models : genotype, phenotype, and dramatype in carcinogenesis
• Expression of Cyclooxygenase mRNA in the Livers of Mice With Interferon-γ Chronic Hepatitis
• Chronic Hepatitis in Interferon-γ Transgenic Mice Is Associated With Elevated CPP32-Like Activity and Interleukin-1β-Converting Enzyme Activity Suppression
• Induction of Fas Ligand and Fas Antigen mRNA Expressions in Interferon-γ Transgenic Mouse Liver
• Induction of Tumor Necrosis Factor-α mRNA in the Kidney of the Mouse Chronic Hepatitis Model
• Induction of TNF-α gene expression in the liver of IFN-γ transgenic mouse
• Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma
• Establishment of novel mAb to human ERC/mesothelin useful for study and diagnosis of ERC/mesothelin-expressing cancers
• Prevention of hereditary carcinogenesis
• Similarity of the secondary structure with identical seven bases in the pregenomic/genomic regions required for the replication of hepatitis B virus and hepatitis C virus
• Deficiency of the Erc/mesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice
• Type 2B-like acquired von Willebrand syndrome
• HCV core protein promotes heparin binding EGF-like growth factor expression and activates Akt

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