IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock

スポンサーリンク

概要

• 論文の詳細を見る

著者

• AKIRA Shizuo

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University

• KAISHO Tsuneyasu

  Department of Host Defense, Research Institute for Microbial Diseases, Osaka University

• Nakanishi Kenji

  Department of Mathematics, Kyoto University

• TSUTSUI Hiroko

  Department of Immunology and Medical Zoology, Hyogo College of Medicine

• OKAMURA Haruki

  Hyogo College of Medicine

• Akira Shizuo

  Department Of Host Defense Research Institute For Microbial Diseases And Akira Innate Immunity Proje

• Takeda K

  Juntendo Univ. Tokyo Jpn

• Takeda Kiyoshi

  Department of Pharmacology, Toho University Faculty of Pharmaceutical Sciences, Japan

• OKAMURA Haruki

  Institute for Advanced Medical Sciences, Hyogo College of Medicine

• Koda T

  Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine Hokkaido Univ

• Okamura Haruki

  Institute For Advanced Medical Sciences Hyogo College Of Medicine

• Akira Shizuo

  Department Of Host Defenses Research Institute For Microbial Diseases Osaka University

• SAKAO Yoshimitsu

  Department of Biochemistry, Hyogo College of Medicine

• NOMURA Fumiko

  Department of Biochemistry, Hyogo College of Medicine

• Tsutsui Hiroko

  Department Of Microbiology Hyogo College Of Medicine

• Tsutsui Hiroko

  Department Of Immunology And Medical Zoology Hyogo College Of Medicine

• Nakanishi K

  Department Of Immunology And Medical Zoology Hyogo College Of Medicine

• Nomura Fumiko

  Department Of Biochemistry Hyogo College Of Medicine

• Akira Shizuo

  Department Of Biochemistry Hyogo College Of Medicine

• Takeda Kiyoshi

  Division Of Immunoregulation Section Of Disease Control Institute For Genetic Medicine Hokkaido Univ

• Nakanishi Kenji

  Department Of Immunology And Medical Zoology Hyogo College Of Medicine

• Nakanishi Kenji

  Department Of Immunology & Medical Zoology Hyogo College Of Medicine

• Takeda Kiyoshi

  Department Of Microbiology And Immunology Graduate School Of Medicine Osaka University

• Takeda Kiyoshi

  Department Of Anesthesia Osaka National Hospital

• Nakanishi Kenji

  Depardtment Of Immunology And Medical Zoology Hyogo College Of Medicine

• Sakao Yoshimitsu

  Department Of Biochemistry Hyogo College Of Medicine

• OKAMURA Haruki

  Institute for Advanced Medical Sciences and the Department of Emergency and Disaster Medicine, Hyogo College of Medicine

関連論文

• The Role of IFN-γ and Toll-Like Receptors in Nephropathy Induced by Toxoplasma gondii Infection
• TLR2 as an essential molecule for protective immunity against Toxoplasma gondii infection
• Endotoxin can induce MyD88-deficient dendritic cells to support T_h2 cell differentiation
• On the global existence of semirelativistic Hartree equations (Harmonic Analysis and Nonlinear Partial Differential Equations)
• Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4-and myeloid differentiation factor 88-dependent signaling pathway
• Electrophysiological and Pharmacological Characteristics of Triggered Activity Elicited in Guinea-Pig Pulmonary Vein Myocardium
• Immunoadjuvant effects of polyadenylic : polyuridylic acids through TLR3 and TLR7
• Contribution of CD1d-unrestricted hepatic DX5^+ NKT cells to liver injury in Plasmodium berghei-parasitized erythrocyte-injected mice
• Roles of caspase-1 in Listeria infection in mice
• IL-18-Mimic Cyclic Peptides Recognized by an Inhibitory Antibody against IL-18 Signaling
• Human Anti-Human IL-18 Antibody Recognizing the IL-18-Binding Site 3 with IL-18 Signaling Blocking Activity
• Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model
• TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
• Mycobacterial Infection in MyD88-Deficient Mice
• Mycobacterial Infection in TLR2 and TLR6 Knockout Mice
• Involvement of Interleukin 18 in Cataract Development in Hereditary Cataract UPL Rats
• Defective IL-2-mediated IL-2 receptor a chain expression in Stat3-deficient T lymphocytes
• P-548 Development of an assay method for anti-allergic effect by using HEL-induced blood flow decrease (Part 2)
• Involvement of the Na^+/Ca^ Exchanger in the Automaticity of Guinea-Pig Pulmonary Vein Myocardium as Revealed by SEA0400
• Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases
• Impaired Postnatal Development in C/EBPβ-deficient Mice
• Entropy-Theoretical Analysis of Glass Transitions in Binary Mixtures
• A regulatory role for suppressor of cytokine signaling-1 in T_h polarization in vivo
• Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways
• IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock
• SDTラットの膵島障害進展におけるマクロファージの役割
• Involvement of Inducible Nitric Oxide Synthase in Blood Flow Decrease in Vein Induced by Hen-Egg White Lysozyme(Miscellaneous)
• Expansion of Lung Vα14 NKT Cells by Administration of α-Galactosylceramidepulsed Dendritic Cells
• Polyl : C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation
• Critical role of the Th1/Tc1 circuit for the generation of tumor-specific CTL during tumor eradication in vivo by Th1-cell therapy
• The interface between innate and acpuired immunity: glycolipid antigen presentation by CD1 d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes
• Functional heterogeneity among bone marrow-derived dendritic cells conditioned by T_h1-and T_h2-biasing cytokines for the generation of allogeneic cytotoxic T lymphocytes
• Natural Killer T Cell Ligand α-Galactosylceramide Inhibited Lymph Node Metastasis of Highly Metastatic melanoma Cells
• Physical and functional interactions between STAT3 and ZIP kinase.
• MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis
• Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis
• Fra-1 negatively regulates lipopolysaccharide-mediated inflammatory responses
• Differential regulation of VLA-2 expression on T_h1 and T_2 cells : a novel marker for the classification of T_h subsets
• An efficient method to prepare T cell receptor gene-transduced cytotoxic T lymphocytes type 1 applicable to tumor gene cell-therapy
• Absence of Toll-Like Receptor-2 Modulates Ventricular Remodeling after Myocardial Infarction
• Acoustic Radiation Induced by Intensity Modulated Ion Beam
• Low Energy Excitations in Simple Molecular Glasses
• Persistent secretion of IL-18 in the skin contributes to IgE response in mice
• Antigen speciflc T cells transduced with interleukin-10 ameliorate experimentally induced arthritis without impairing systemic immune response to the antigen
• Autoreactive T cells as a therapeutic vehicle
• Ikk-i, a novel Lipopolysaccharide-inducible kinase that is realted to lκB Kinases
• Pathological role of Toll-like receptor signaling in cerebral malaria
• Differential involvement of IFN-β in Toll-like receptor-stimulated dendritic cell activation
• A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways
• Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
• Effect of Exercise on Endotoxin Shock with Special Reference to Changes in Concentration of Cytokines
• Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to V_α14 NKT cells
• A novel recognition motif of human NKT antigen receptor for a glycolipid ligand
• Freshly isolated Langerhans cells negatively regulate naive T cell activation in response to peptide antigen through cell-to-cell contact
• IL-12 synergizes with IL-18 or IL-1β for IFN-γ production form human T cells
• Discrimination of bacterial lipoproteins by Toll-like receptor 6
• Granzyme B is a novel interleukin-18 converting enzyme
• The genomic structure and chromosomal localization of the mouse STAT3 gene
• Distribution of Methanotrophic Bacteria in the Coastal Marine Sediments
• Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
• Formation of Aluminium Nitride by Nitrogen-Ion Implantation in Aluminium Single Crystal
• Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice
• Antiviral Signaling Through Pattern Recognition Receptors
• IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8
• Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins
• Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis
• Inducible expression of nuclear factor IL-6 increases endogenous gene expression of macrophage inflammatory protein-1α, osteopontin and CD14 in a monocytic leukemia cell line
• Modulation of Doxorubicin-lnduced Cardiac Dysfunction in Toll-Like Receptor 2 Knock-Out Mice
• IFN-γ is a master regulator of endotoxin shock syndrome in mice primed with heat-killed Propionibacterium acnes
• Targeting solid tumors with non-pathogenic obligate anaerobic bacteria
• Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/Ipr mice
• Mizoribine protects against bleomycin-induced lung injury
• IL-4 and anti-CD40 prtect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation
• Three Cases of Chemotherapy-induced Acral Erythema
• TNF signalings as pleiotropic gates in the liver
• S-I-1 Regulation of Inflammatory Responses by Nuclear IkB Proteins(S-I: Trigger of Inflammation: Up and Down of TLRs,Symposia,8^ INTERNATIONAL SOCIETY OF EXERCISE AND IMMUNOLOGY SYMPOSIUM,ISEI2007 INFLAMMATION IN EXERCISE FRIEND OR FOE?)
• IL-2 inhibits IL-4-dependent IgE and IgG1 production in vitro and in vivo
• Regulation of host immune responses by nuclear IκB proteins
• Aging Transition and Universal Scaling in Globally Coupled Oscillators(Oscillation, Chaos and Network Dynamics in Nonlinear Science)
• Contribution of IL-18-induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness
• Mammalian Innate Immune System and Viral Infection(Keynote lecture,8^ INTERNATIONAL SOCIETY OF EXERCISE AND IMMUNOLOGY SYMPOSIUM,ISEI2007 INFLAMMATION IN EXERCISE FRIEND OR FOE?)
• Toll-like receptors in innate immunity
• Microbial recognition by Toll-like receptors
• Accidental penetration of a vocal cord by a nasogastric tube
• Remarks on the energy scattering for nonlinear Klein-Gordon andSchrodinger equations
• Development of Model Materials for Physical Forming Simulation of Metals and Alloys
• Role of nuclear IκB proteins in the regulation of host immune responses
• The Malarial Metabolite Hemozoin and Its Potential Use as a Vaccine Adjuvant
• Electrophysiological and Pharmacological Characteristics of Triggered Activity Elicited in Guinea-Pig Pulmonary Vein Myocardium
• Importance of IL-18-Induced Super Th1 Cells for the Development of Allergic Inflammation
• Electrophysiological Effects of the Class Ic Antiarrhythmic Drug Pilsicainide on the Guinea-Pig Pulmonary Vein Myocardium
• Roles of IL-18 in Basophils and Mast Cells
• GLOBAL SOLUTIONS FOR NONLINEAR SCHRÖDINGER EQUATIONS WITH ARBITRARILY GROWING NONLINEARITY AND CONTRACTED INITIAL DATA
• Electrophysiological Effects of the Antiarrhythmic Drug Bepridil on the Guinea-Pig Pulmonary Vein Myocardium

もっと見る 閉じる

スポンサーリンク