HASHIMOTO Yukiya | Graduate School of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

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概要

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著作論文

Evaluation of Phenytoin Dosage Regimens Based on Genotyping of CYP2C Subfamily in Routinely Treated Japanese Patients
Inhibitory and Stimulative Effects of Amiodarone on Metabolism of Carvedilol in Human Liver Microsomes
Involvement of the CYP1A Subfamily in Stereoselective Metabolism of Carvedilol in β-Naphthoflavone-Treated Caco-2 Cells(Biopharmacy)
Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Metoprolol in Routinely Treated Japanese Patients(Biopharmacy)
Pharmacokinetic Characterization of Transcellular Transport and Drug Interaction of Digoxin in Caco-2 Cell Monolayers(Biopharmacy)
OJ-003 Influences of CYP2D6 Genotype on Plasma Concentrations of Carvedilol : a Comparison with Metoprolol and Bisoprolol(Cardiovascular pharmacology, basic/clinical-2 (H) OJ1,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of
Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Routinely Administered Bepridil in Japanese Patients with Arrhythmias(Biopharmacy)
Analysis of CYP2D6 Genotype in Relation to Bepridil Pharmacokinetics in Patients with Persistent Atrial Fibrillation(Arrhythmia, Pharmacological Therapy 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
Pharmacokinetic Variability of Routinely Administered Bisoprolol in Middle-Aged and Elderly Japanese Patients(Biopharmacy)
The Genotype of CYP2D6 Determines Cardiac Responsiveness to β-adrenergic Stimulation in patients Treated with Metoprolol, but not with Bisoprolol(Cardiovascular Pharmacology, Basic/Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circula
Pharmacokinetics of R- and S-Carvedilol in Routinely Treated Japanese Patients with Heart Failure(Biopharmacy)
Effect of CYP2D6^*10 on the Pharmacokinetics of R- and S-Carvedilol in Healthy Japanese Volunteers(Biopharmacy)
Population Pharmacokinetics of Higher-Dose Mizoribine in Healthy Male Volunteers(Biopharmacy)
Intestinal Expression and Metabolic Activity of the CYP3A Subfamily in Female Rats(Biopharmacy)
Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Aripiprazole in Healthy Japanese Males(Biopharmacy)
Membrane Transport Mechanisms of Mizoribine in the Rat Intestine and Human Epithelial LS180 Cells(Biopharmacy)
The Apical Uptake Transporter of Levofloxacin is Distinct from the Peptide Transporter in Human Intestinal Epithelial Caco-2 Cells
Directional Transcellular Transport of Bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 Cells, but not in Renal Epithelial LLC-PK_1 Cells
Stereoselective Oxidation and Glucuronidation of Carvedilol in Human Liver and Intestinal Microsomes(Biopharmacy)
Additional Notes on Clinical Repeated-Dose Pharmacokinetic Trials Applying a Peak-and-Trough Sampling Design to Estimate Oral Clearance
Population Pharmacokinetics and Proton Pump Inhibitory Effects of Intravenous Lansoprazole in Healthy Japanese Males(Analytical Biochemistry)
Pharmacokinetic Analysis of Transcellular Transport of Levofloxacin across LLC-PK_1 and Caco-2 Cell Monolayers(Biopharmacy)
Simulation for Clinical Repeated-Dose Pharmacokinetic Trials Applying a Peak-and-Trough Sampling Design to Estimate Oral Clearance(Biopharmacy)
UGT2B7^*3はR-, S-カルベジロールの体内動態に影響を及ぼさない
LS180細胞におけるVDRリガンドのCYP3A4発現誘導活性の評価
Pharmacokinetics and Hepatic Extraction of Metoprolol in Rats with Glycerol-Induced Acute Renal Failure(Biopharmacy)
尿管結紮腎不全モデルラットにおけるビソプロロールの体内動態と薬効の解析
Endogenous Uremic Substances are not Involved in the Reduced Hepatic Extraction of Metoprolol in Bilateral Ureter-Ligated Rats
Multiple Regression Analysis of Pharmacogenetic Variability of Carvedilol Disposition in 54 Healthy Japanese Volunteers(Biopharmacy)
Pharmacokinetic Analysis of Transcellular Transport of Quinidine across Monolayers of Human Intestinal Epithelial Caco-2 Cells(Biopharmacy)
OJ-326 The Genotype of CYP2D6 Determines the Cardiovascular Responsiveness to Isoproterenol in Patients Treated with Metoprolol(Cardiovascular Pharmacology, Basic/Clinical 2 (H) : OJ39)(Oral Presentation (Japanese))
Intestinal Absorption and Hepatic Extraction of Propranolol and Metoprolol in Rats with Bilateral Ureteral Ligation(Biopharmacy)
A Simulation Study to Evaluate Limited Sampling Strategies to Estimate Area under the Curve of Drug Concentration versus Time Following Repetitive Oral Dosing: Limited Sampling Model versus Naive Trapezoidal Method

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