Nishimura Masuhiro | Department Of Drug Metabolism Division Of Pharmacology Drug Safety And Metabolism Otsuka Pharmaceuti

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著作論文

Pharmacological assessment of ARTCEREB_【○!R】 irrigation and perfusion solution for cerebrospinal surgery using primary cultures of rat brain cells
Comparative analysis of ATP-binding cassette (ABC) transporter gene expression levels in peripheral blood leukocytes and in liver with hepatocellular carcinoma
Cytochrome P450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver
Perfusion fluids used in neurosurgery affect cerebrospinal fluid and surrounding brain parenchyma in the rat ventriculocisternal perfusion model
Effects of NO-1886 (Ibrolipim), a Lipoprotein Lipase-Promoting Agent, on Gene Induction of Cytochrome P450s, Carboxylesterases, and Sulfotransferases in Primary Cultures of Human Hepatocytes
Influence of Albumin on Enantioselective Local Disposition of BOF-4272,a Xanthine Oxidase Inhibitor with Chiral Sulfoxide, in Rat Liver
Hepatic Local Disposition of a Drug with High Protein Binding and High Hepatic Clearance Using BOF-4272 as a Model Drug
カニクイザルにおける薬物代謝酵素およびトランスポーターmRNAの組織発現プロファイル
ヒト組織におけるトランスポーター-SLC35ファミリーのmRNA発現プロファイル
Comparison of Inducibility of Multidrug Resistance (MDR)1, Multidrug Resistance-Associated Protein (MRP)1, and MRP2 mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes(Pharmacology)
Comparison of Inducibility of Sulfotransferase and UDP-Glucuronosyltransferase mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes
One-Point サンプリングデータのブートストラップ法による薬物速度論パラメータのヒストグラム解析
Soybean Oil Fat Emulsion to Prevent TPN-Induced Liver Damage : Possible Molecular Mechanisms and Clinical Implications
Assessment of Induction of Cytochrome P450 by NO-1886 (Ibrolipim), a Lipoprotein Lipase-Promoting Agent, in Primary Cultures of Human Hepatocytes and in Female Rat Liver
Major Role of Soybean Oil in Preventing Decrease in CYP4A1 mRNA Content Relative to PPARα mRNA Down-Regulation in Infant Rats(Pharmacology)
Soybean Oil in Total Parenteral Nutrition Maintains Albumin and Antioxidant Enzyme mRNA Levels(Biopharmacy)
Expression of Multidrug Resistance Proteins and Accumulation of Cisplatin in Human Non-small Cell Lung Cancer Cells(Biopharmacy)
Role of Soybean Oil Fat Emulsion in the Prevention of Hepatic Xenobiotic Transporter mRNA Up- and Down-Regulation Induced by Overdose of Fat-free Total Parenteral Nutrition in Infant Rats
Soybean Oil Fat Emulsion Prevents Cytochrome P450 mRNA Down-Regulation Induced by Fat-Free Overdose Total Parenteral Nutrition in Infant Rats(Biopharmacy)
Effects of Pretreatment of Hep G2 Cells with β-Naphthoflavone on Cytotoxicity of Propranolol and its Active Metabolite 4-Hydroxypropranolol
Effects of Dimethyl Sulfoxide on the Gene Induction of Cytochrome P450 Isoforms, UGT-Dependent Glucuronosyl Transferase Isoforms, and ABCB1 in Primary Culture of Human Hepatocytes
資料 Tissue Distribution of mRNA Expression of Human Cytochrome P450 Isoforms Assessed by High-Sensitivity Real-Time Reverse Transcription PCR
Effects of Dimethyl Sulphoxide and Dexamethasone on mRNA Expression of Myogenesis- and Muscle Proteolytic System-related Genes in Mouse Myoblastic C2C12 Cells
Intrathecal Disposition of ARTCEREB® Irrigation and Perfusion Solution for Cerebrospinal Surgery in Rats
ヒトの肝細胞培養系を用いた新薬候補化合物曝露のCYP1A2およびCYP3A4誘導能の評価
Enhancement of Myofibrillar Proteolysis Following Infusion of Amino Acid Mixture Correlates Positively with Elevation of Core Body Temperature in Rats
Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight
Secretion of Albumin and Induction of CYP1A2 and CYP3A4 in Novel Three-dimensional Culture System for Human Hepatocytes using Micro-space Plate
Induction of Human CYP1A2 and CYP3A4 in Primary Culture of Hepatocytes from Chimeric Mice with Humanized Liver
Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver
Tissue-specific mRNA Expression Profiles of Human Nuclear Receptor Subfamilies
Metabolic Pathways and Pharmacokinetics of BOF-4272,a Sulfoxide-Containing Drug, in the Dog : In Vivo and in Vitro Studies

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