酵素機構研究への有機化学的アプロ-チ--"逆性基質"によるトリプシンの研究を中心に
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概要
著者
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谷沢 和隆
Faculty of Pharmaceutical Sciences, Hokkaido University
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谷沢 和隆
Faculty Of Pharmaceutical Sciences Hokkaido University
関連論文
- Kinetic Study on the Mechanism of Inhibition of Trypsin and Trypsin-like Enzymes by p-Guanidinobenzoate Ester
- Fluorescence Labeled and Cross-Linked Subtilisin : Kinetic Characteristics and Binding to Streptomyces Subtilisin Inhibitor
- Preparation of Fluorescence-Labeled and Cross-Linked Subtilisin
- Inverse Substrates. XV. Spectrometric Properties of Fluorescence-labeled Acyl Trypsins
- Inverse Substrates. IX. Amidinophenyl Esters derived from Amino Acids and Peptides : Synthesis and Properties as Trypsin Substrates
- Proteolytic Enzymes. V. Further Application of p-Nitrophenyl p-Amidinobenzoate as a Titrant of Trypsin
- Proteolytic Emzymes. III. trans-4-Aminomethylcyclohexane-1-carboxylic Acid Derivatives as Substrates and an Active Site Titrant of Trypsin
- Proteolytic Enzymes. II. Studies on the Requirement for the Active Center of Trypsin with Amidinobenzoates as Substrates
- New Fluorogenic Substrates for Subtilisin
- Comparison of Deacylation Rates of Chymotryptic Catalysis within an Enantiomeric Pair of p-Nitrophenyl Esters
- Introduction of γ-Glutamyl Residue into Chymotrypsin and Agarose Gel : Application to Cross-Linking and Immobilization of Protein
- Dansylation of Streptomyces Subtilisin Inhibitor : Spectrometric Analysis of the Fluorescence-Labeled Inhibitor
- Schiff Base Copper(II) : Chelate as a Tool for Immobilization of Protein
- Diketene Analogs as β-Lactamase Inhibitor
- Synthesis and Physicochemical Properties of Cyclic Peptides
- Comparative Studies on the Stability of Acyl Enzyme Intermediates : An Approach to the Design of Temporary Inhibitors for Trypsin-like Enzymes
- トリプシン"逆性基質"概念の確立.酵素研究及び新生理活性物質開発への応用
- Predominant Transesterification Reaction Catalyzed by Immobilized Trypsin
- 酵素を化学で考える (生命と化学--その接点を考える) -- (生命を化学で考える)
- 酸素による基質の認識とその応用 (分子の認識と機能の発現)
- Efficient Tryptic Hydrolysis of Aryl Esters with a Cationic Center in the Leaving Group. Further Characterization of"Inverse Substrates"
- アフィニティラベルに利用できる有機反応 (アフィニティクロマトとアフィニティラベル) -- (アフィニティクロマトグラフィ-)
- 加水分解酵素研究の新しい有機化学的アプロ-チ,"逆性基質"--機能性分子設計の一例
- 酵素機構研究への有機化学的アプロ-チ--"逆性基質"によるトリプシンの研究を中心に
- Studies on Protein-Sulfhydryl Reagents. I. Synthesis of Benzimidazole Derivatives of Maleimide ; Fluorescent Labeling of Maleimide.
- Polyphosphate Ester as a Synthetic Agent. XII. A Convenient Synthesis of Nitriles by the Dehydration of Amides with PPE
- Polyphosphate Ester as a Synthetic Agent. XI. Synthesis of 2-(1'-Aminoalkyl) benzimidazoles from N-Benzoylamino Acids
- Polyphosphate Ester as a Synthetic Agent. IV. A Novel Preparation of Aryl Esters
- “逆性基質”によるトリプシンの解析
- Polyphosphate Esters as Synthetic Reagent. I. Synthesis of 2-Substituted Benzimidazoles
- 生物化学--トリプシン研究の進歩 (1975年の化学-12完-)