A Case of Diffuse Interstitial Pneumonia Complicated by Hashimoto's Disease, Vitiligo and Eruption

概要

論文の詳細を見る
A 53 year old female was admitted on May,1982 having been suffered from dry cough and shortness of breath on exertion for a month. She had been pointed out the abnormal shadow on her chest X-ray film for last six months. She was recommended our clinic for detail examination. Lab. data: RA (+), CRP (± +), ESR (1hr. ) 83mm, γ-gl.26.8%, LDH 845u, CPK 779u, PaO2 66.7mmHg, T4.4.8μg/d1, T3 0.7μg/d1, TSH 50.4μu/ml. Her diffuse enlarged goiter and thyroid function diagnosed as Hashimoto's disease. The abnormal shadow on her chest X-ray film revealed diffuse interstitial pneumonia by trans bronchial lung biopsy (TBLB). On admission, she was treated with 40mg of predonisolone daily, which was gradually tapered. She showed improvement in her subjective and objective symptome. The possibility that idiopathic interstitial pneumonia is pathogenetically related to autoimmune reactions has been considered frequently. Hashimoto's disease is a representative autoimmune disease, and Vitiligo relates to autoimmune disease. Our case had Hashimoto's disease, vitiligo and idiopathic interstitial pneumonia. We considered that these diseases were not accidental complication, the pathogenesis of idiopathic interstitial pneumonia related to autoimmune factors.
The Medical Society of Kansai Medical Universityの論文