In Vitro Antibiotic Susceptibility of Francisella tularensis Isolates from Japan
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概要
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The antibiotic susceptibilities of 36 isolates of Japanese Francisella tularensis, an etiological agent of the zoonotic disease tularemia, were analyzed using the E test. All the isolates were susceptible to ciprofloxacin, doxycycline, erythromycin, and gentamicin but resistant to benzylpenicillin and cephalothin. The susceptibility to seven other β-lactams (aztreonam, cefotaxime, cefoxitin, ceftriaxone, cefuroxime, imipenem, and meropenem) varied among the isolates. These findings suggest that the guidelines for the antibiotic treatment of tularemia issued by the World Health Organization are appropriate for Japanese tularemia patients.
著者
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Hotta Akitoyo
Department Of Veterinary Microbiology Faculty Of Agriculture Gifu University
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Uda Akihiko
Department Of Veterinary Science National Institute Of Infectious Diseases
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Tanabayashi Kiyoshi
Department Of Veterinary Science National Institute Of Infectious Diseases
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Morikawa Shigeru
Department Of Bacteriology And Department Of Pathology Chest Disease Research Institute Kyoto Univer
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Yamamoto Yoshie
Department Of Veterinary Science
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Fujita Osamu
Department of Bioresources Science and Technology, Graduate School of Biosphere Science, Hiroshima University
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Yamada Akio
Laboratory of Veterinary Public Health, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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Sharma Neekun
Department of Veterinary Science, National Institute of Infectious Diseases
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