Prevalence and Risk Factors of Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Children in Japan

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概要

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• The findings of this study revealed a 22% prevalence of Streptococcus pneumoniae among healthy children in Japan; the prevalence tended to increase with age. We identified attendance at day-care facilities and the presence of older siblings as the major risk factors associated with pneumococcal carriage. A significant decrease in pneumococcal colonization was observed among children during the summer; however, a seasonal variation was independent of various factors. Our findings suggest that prior immunization with heptavalent pneumococcal conjugate vaccine within the current recommended schedule is required for children exposed to these risk factors.

著者

• Chang Bin

  Department Of Bacteriology National Institute Of Infectious Diseases

• Tateda Kazuhiro

  Department Of Microbiology And Infectious Disease Toho University School Of Medicine

• Ueno Masahiro

  Department Of Cardiovascular Surgery Kagoshima University Graduate School Of Medical And Dental Scie

• Ishii Yoshikazu

  Department Of Microbiology And Infectious Disease Toho University School Of Medicine

• Sugita Minoru

  Department Of Biology School Of Education Waseda University

• Suzuki Yoko

  Department Of Cardiology National Maiduru Hospital

• NISHIWAKI Yuji

  Department of Environmental and Occupational Health, Faculty of Medicine, Toho University

• TANAKA Taichiro

  Department of Health Science, Shiga University of Medical Science

• Ebata Akiko

  Department of Bacteriology, Ageo Medical Laboratories, Inc.

• Ueno Masahiro

  Department of Environmental and Occupational Health, School of Medicine, Toho University

• Anahara Yoshiko

  Department of Bacteriology, Ageo Medical Laboratories, Inc.

• Iida Masaei

  Department of Bacteriology, Ageo Medical Laboratories, Inc.

• Inamura Seiko

  Yashio Ekimae Internal Medicine and Pediatric Clinic

• Takahata Kahori

  Department of Pediatrics, Tokyo Women's Medical University Medical Center East

• Wada Akihito

  Yonaguni Medical Clinic

• Chang Bin

  Department of Bacteriology I, National Institute of Infectious Diseases

• Takahata Kahori

  Department of Pediatrics, Tokyo Women's Medical University Medical Center East

• Tateda Kazuhiro

  Department of Microbiology and Infectious Diseases, School of Medicine, Toho University

• Nishiwaki Yuji

  Department of Environmental and Occupational Health, School of Medicine, Toho University

• Sugita Minoru

  Department of Environmental and Occupational Health, School of Medicine, Toho University

• Tanaka Taichiro

  Department of Environmental and Occupational Health, School of Medicine, Toho University

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