The Genetic Diversity of Merozoite Surface Antigen 1 (MSA-1) among Babesia bovis detected from Cattle Populations in Thailand, Brazil and Ghana
スポンサーリンク
概要
- 論文の詳細を見る
In the present study, we screened blood DNA samples obtained from cattle bred in Brazil (n=164) and Ghana (n=80) for Babesia bovis using a diagnostic PCR assay and found prevalences of 14.6% and 46.3%, respectively. Subsequently, the genetic diversity of B. bovis in Thailand, Brazil and Ghana was analyzed, based on the DNA sequence of merozoite surface antigen-1 (MSA-1). In Thailand, MSA-1 sequences were relatively conserved and found in a single clade of the phylogram, while Brazilian MSA-1 sequences showed high genetic diversity and were dispersed across three different clades. In contrast, the sequences from Ghanaian samples were detected in two different clades, one of which contained only a single Ghanaian sequence. The identities among the MSA-1 sequences from Thailand, Brazil and Ghana were 99.0–100%, 57.5–99.4% and 60.3–100%, respectively, while the similarities among the deduced MSA-1 amino acid sequences within the respective countries were 98.4–100%, 59.4–99.7% and 58.7–100%, respectively. These observations suggested that the genetic diversity of B. bovis based on MSA-1 sequences was higher in Brazil and Ghana than in Thailand. The current data highlight the importance of conducting extensive studies on the genetic diversity of B. bovis before designing immune control strategies in each surveyed country.
著者
-
Igarashi Ikuo
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
-
Sivakumar Thillaiampalam
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
-
Yokoyama Naoaki
National Research Center For Protozoan Diseases Obihiro University Of Agriculture And Veterinary Med
-
DE DE
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080–8555, Japan
-
NAGANO Daisuke
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080–8555, Japan
-
YOKOYAMA Naoaki
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido 080–8555, Japan
-
INPANKAEW Tawin
Department of Parasitology, Faculty Medicine, Kasetsart University, Bangkok, Thailand
-
ALHASSAN Andy
Veterinary Services Laboratory, Accra, Ghana
関連論文
- フタトゲチマダニの吸血に対するスカベンジャーレセプターノックアウト(SRKO)マウスの免疫応答と抵抗性獲得
- Genotypic Diversity of Theileria orientalis Detected from Cattle Grazing in Kumamoto and Okinawa Prefectures of Japan
- Epidemiological Survey of Theileria orientalis Infection in Grazing Cattle in the Eastern Part of Hokkaido, Japan
- Contribution of Complement Component C3 and Complement Receptor Type 3 to Carbohydrate-dependent Uptake of Oligomannose-coated Liposomes by Peritoneal Macrophages
- Comparison of Two Hemoplasma Species on Hematological Parameters in Cattle
- Molecular Epidemiological Survey of Theileria orientalis in Thua Thien Hue Province, Vietnam
- Expression Patterns of the Implantation-associated Genes in the Uterus during the Estrous Cycle in Mice
- マウスの発情周期における着床関連遺伝子の発現について
- Detection of the New Ehrlichia Species Closely Related to Ehrlichia ewingii from Haemaphysalis longicornis in Yonaguni Island, Okinawa, Japan
- Artesunate, a potential drug for treatment of Babesia infection
- Inhibitory effect of terpene nerolidol on the growth of Babesia parasites
- Comparison of Macrophage Scavenger Receptor-A Knockout Mice with Wild Type Ones in the Immune Response against Repeated Infestation with Haemaphysalis longicornis
- Involvement of a Host Erythrocyte Sialic Acid Content in Babesia bovis Infection
- A PCR Based Survey of Babesia ovata in Cattle from Various Asian, African, and South American Countries
- Dual Presence of Anaplasma phagocytophilum and Its Closely Related Anaplasma sp. in Ixodid Ticks in Hokkaido, Japan, and Their Specific Molecular Detection
- Prevalence and Risk Factor Analysis of Bovine Hemoplasma Infection by Direct PCR in Eastern Hokkaido, Japan
- Downregulation of Hepatic Cytochrome P450 3A in Mice Infected with Babesia microti
- First Molecular Characterization of Anaplasma marginale in Cattle and Rhipicephalus (Boophilus) microplus Ticks in Cebu, Philippines
- A Clinical Case of Severe Anemia in a Sheep Coinfected with Mycoplasma ovis and Candidatus Mycoplasma haemovis' in Hokkaido, Japan
- The Genetic Diversity of Merozoite Surface Antigen 1 (MSA-1) among Babesia bovis detected from Cattle Populations in Thailand, Brazil and Ghana
- PCR Detection and Genetic Diversity of Bovine Hemoprotozoan Parasites in Vietnam
- Specific Molecular Detection and Characterization of Anaplasma marginale in Mongolian Cattle
- Molecular Epidemiological Survey of Benign Theileria Parasites of Cattle in Japan: Detection of a New Type of Major Piroplasm Surface Protein Gene
- Babesia bovis Dihydroorotate Dehydrogenase (BboDHODH) is a Novel Molecular Target of Drug for Bovine Babesiosis
- Prevalence and Molecular Analyses of Hemotrophic Mycoplasma spp. (Hemoplasmas) Detected in Sika Deer (Cervus nippon yesoensis) in Japan
- Epidemiological Investigation of Equine Piroplasmosis in China by Enzyme-Linked Immunosorbent Assays