Stereoselective .ALPHA.-glucosylation with tetra-O-benzyl-.ALPHA.-D-glucose and a mixture of trimethylsilyl bromide, cobalt(II) bromide, tetrabutylammonium bromide, and a molecular sieve. A synthesis of 3,6-di-O-(.ALPHA.-D-glucopyranosyl)-D-glucose.
スポンサーリンク
概要
- 論文の詳細を見る
A mixture of trimethylsilyl bromide, cobalt(II) bromide, tetrabutylammonium bromide, and a molecular sieve (4A) is effective for the stereoselective, one-stage α-glucosylation of alcohol with 2,3,4,6-tetra-<I>O</I>-benzyl-α-D-glucopyranose in dichloromethane. Using this procedure, several disaccharide derivatives as well as <I>O</I>-α-D-glucopyranosyl-(1→3)]-<I>O</I>-[α-D-glucopyranosyl-(1→6)]-D-glucopyranose are synthesized.
- 公益社団法人 日本化学会の論文
著者
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YOSHIDA Toyosaku
School of Pharmaceutical Sciences, Kitasato University
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Zen Shonosuke
School Of Pharmaceutical Sciences Kitasato University
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Koto Shinkiti
School Of Pharmaceutical Sciences Kitasato University
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Morishima Naohiko
School Of Nursing Kitasato University
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Kusuhara Chiharu
School of Pharmaceutical Sciences, Kitasato University
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Sekido Shigeko
School of Pharmaceutical Sciences, Kitasato University
関連論文
- Benzyl Derivatives of N-2,4-Dinitrophenyl-D-glucosamine and Their Use for Oligosaccharide Synthesis
- Syntheses of Penta-O-benzyl-myo-inositols, O-β-L-Arabinosyl-(1→2)-sn-myo-inositol, O-α-D-Galactosyl-(1→3)-sn-myo-inositol, and O-α-D-Galactosyl-(1→6)-O-α-D-Galactosyl-(1→3)-sn-myo-inositol
- Glycosylation Using 2-Azido-3,4,6-tri-ο-benzyl-2-deoxy-D-glucose,-galactose, and -mannose with the Aid of ρ-Nitrobenzenesulfonyl Chloride-Silver Trifluoromethanesulfonate-Triethylamine System
- Synthesis of Glucose-Containing Linear Oligosaccharides Having α(1→4) and α(1→6) Linkages Using Stereoselective Dehydrative Glycosylation
- Synthesis and Utility of 2-(Benzoyloxyimino)-2-deoxy-α-D-lyxo-hexopyranosyl Bromide as a Novel α-D-Talosaminide Building Block
- A Practical Synthesis of Mannosaminyl-β(1→4)-glucosyl-α(1→2)-rhamnose, the Trisaccharide Repeating Unit of a Streptococcus pneumoniae Capsular Polysaccharide
- Synthesis of a 2-Acetamido-2-deoxy-β-D-mannuronic Acid-Containing Artificial Glycolipid Corresponding to the Repeating Unit of Teichuronic Acid from Micrococcus luteus
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- Expedient Synthesis of an Anomerically Modified Trisaccharide Component of the Capsular Polysaccharide from Streptococcus pneumoniae Type 19F
- Synthesis of β-D-Ribofuranosyl-(1→3)-α-L-rhamnopyranosyl-(1→3)-L-rhamnopyranose by in situ Activating Glycosylation Using 1-OH Sugar Derivative and Me_3SiBr-CoBr_2-Bu_4NBr-Molecular Sieves 4A System
- Biochemical Characterization of Bovine Lactoferrin as a Glycyrrhizin-Binding Protein in Vitro
- Glycosylation Using Hemiacetal Sugar Derivatives : Synthesis of O-α-D-Rhamnosyl-(1→3)-O-α-D-rhamnosyl-(1→2)-D-rhamnose and O-α-D-Tyvelosyl-(1→3)-O-α-D-mannosyl-(1→4)-L-rhamnose
- A Novel, Readily Accessible Lactosaminyl Donor : N-Trichloroethoxycarbonyl-hexa-0-benzoyl-β-D-lactosaminyl Fluoride :
- Syntheses of O-β-D-Mannosyl-(1→4)-O-α-D-mannosyl-(1→3)-L-rhamnose and O-(2-Acetamido-2-deoxy-β-D-mannosyl)-(1→4)-O-α-D-galactosyl-(1→4)-D-galactose via In-situ-activating Glycosylation Using 2-O-Acetyl-3, 4, 6-tri-O-benzyl-D-glucose
- Stereoselective Syntheses of α-Glucuronides Using Dehydrative Glycosylation
- Synthesis of Methyl O -IX- D Mannosyl (1→4)-[(3-O-methyl-α-D-mannosyl)-(1→4) ]_n 3-O methyl-α-D-mannosides (n=O, 1, and 2) via Dehydrative Glycosylation
- Dehydrative Glycosylation by Diethylaminosulfur Trifluoride (DAST)-Tin(II) Trifluoromethanesulfonate-Tetrabutylammonium Perchlorate-Triethylamine System
- In situ Activating Glycosylation of 6-Deoxysugars: Synthesis of O-α-_D-Fucosyl-(1→4)-O-α-_D-fucosyl-(1→4)-O-α-_D-quinovosyl-(1→4)-_D-quinovose
- Syntheses of Isomaltose, Isomaltotetraose, and Isomaltooctaose
- A study of the rapid anomerization of poly-O-benzyl-.BETA.-D-glucopyranosides with titanium tetrachloride.
- A stereoselective one-stage .ALPHA.-glucosylation with 2,3,4,6-tetra-O-benzyl-.ALPHA.-D-glucopyranose and a mixture of methanesulfonic acid, cobalt(II) bromide, and tetraethylammonium perchlorate.
- The direct synthesis of methyl 2,4-di-O-benzyl-.ALPHA.-D-xylopyranoside by the regiospecific benzylation of methyl .ALPHA.-D-xylopyranoside.
- Synthesis of O-.BETA.-D-glucopyranosyl-(1.RAR.2)-O-.BETA.-D-glucopyranosyl-(1.RAR.6)-D-glucopyranose; Dehydrative .BETA.-D-glucosylation using 2-O-acetyl-3,4,6-tri-O-benzyl-D-glucopyranose.
- The synthesis of .ALPHA.-D-galactopyranosyl and .ALPHA.-D-mannopyranosyl 2-amino-2-deoxy-.ALPHA.-D-glucopyranosides and the conformation of their glycoside linkage.
- .ALPHA.-D-glucosylation by 6-O-acetyl-2,3,4-tri-O-benzyl-D-glucopyranose using trimethylsilyl triflate and pyridine. Synthesis of .ALPHA.-maltosyl and .ALPHA.-isomaltosyl .ALPHA.-D-glucosides.
- Partial benzylation of methyl .ALPHA.- and .BETA.-D-galactopyranosides.
- Stereoselective synthesis of mixed acetal glycosides by reaction of tri-O-acetyl-N-(2,4-dinitrophenyl)-.ALPHA.-D-glucosaminyl bromide with alcohol in acetone.
- A through-process for the preparation of methyl per-O-acetyl 1-thio-glycosides from aldoses.
- Synthesis of Anomeric Methyl 6-O-(L-Mycarosyl)-β-D-glucosaminides and 4-O-(L-Mycarosyl)-β-D-mycaminosides
- The Synthesis of Methyl 2,4,6-Tri-O-benzyl-α-D-glucopyranoside
- Partially benzylated derivatives of 6-deoxy-D-glucose.
- .ALPHA.-Glucosylation of phenols with tetra-O-benzyl-.ALPHA.-D-glucose.
- The stereoselective dehydrative .ALPHA.-glucosylation using 6-O-acetyl- and 6-O-p-nitrobenzoyl-2,3,4-tri-O-benzyl-D-glucopyranoses.
- Synthesis of 4-Substituted Isoxazole-3,5-dicarboxylic Acids from 2-Substituted-1,3-dinitroglutarates and the Reaction Mechanism therefrom
- Glucosidation of tetra-O-benzyl-.ALPHA.-D-glucose with chlorosilane and silver sulfonate.
- Preparation of 2,3,4,6-tetra-O-benzyl-D-mannose.
- The Synthesis of Purine Nucleosides of L-Mycarose and L-Cladinose
- Stereoselective .ALPHA.-glucosylation with tetra-O-benzyl-.ALPHA.-D-glucose and a mixture of trimethylsilyl bromide, cobalt(II) bromide, tetrabutylammonium bromide, and a molecular sieve. A synthesis of 3,6-di-O-(.ALPHA.-D-glucopyranosyl)-D-glucose.
- The Synthesis of 3-Amino-3-deoxy-D-allose and Related Substances
- 2-methoxyethyl group for protection of reducing hydroxyl group of aldose.
- Studies on 5-8 fused ring compounds. V. The conformations of eight-membered rings in 5-8-5 fused ring compounds and their cis-trans isomerization.
- The glucosylation of several alcohols with tetra-O-benzyl-.ALPHA.-D-glucopyranose and a mixture of p-nitrobenzenesulfonyl chloride, silver trifluoromethanesulfonate, and triethylamine.
- A facile synthesis of anomeric methyl DL-tolyposaminides, methyl DL-forosaminides, and related substances.