Synthesis of Anomeric Methyl 6-<I>O</I>-(L-Mycarosyl)-β-D-glucosaminides and 4-<I>O</I>-(L-Mycarosyl)-β-D-mycaminosides
スポンサーリンク
概要
- 論文の詳細を見る
Condensation of 3,4-<I>O</I>-carbonyl-2,6-dideoxy-3-<I>C</I>-methyl-L-<I>ribo</I>hexopyranosyl chloride (III) with methyl 2-deoxy-2-(2,4-dinitroanilino)-β-D-glucopyranoside and the subsequent removal of blocking groups gave the anomeric isomers of methyl 6-<I>O</I>-(2,6-dideoxy-3-<I>C</I>-methyl-L-<I>ribo</I>hexopyranosyl)-2-amino-2-deoxy-β-D-glucopy-ranoside (VIIa, VIIb). On the other hand, the condensation of III with methyl 3,6-dideoxy-3-(<I>N</I>-methylcarboethoxyamino)-2-<I>O</I>-<I>p</I>-phenylazobenzoyl-β-D-glucopyranoside (XI) followed by removal of the acyl groups and <I>N</I>-methylation afforded the anomeric forms of methyl 4-<I>O</I>-(2,6-dideoxy-3-<I>C</I>-methyl-L-<I>ribo</I>hexopyranosyl)-3,6-dideoxy-3-dimethylamino-β-D-glucopyranoside (XVa, XVb).
- 公益社団法人 日本化学会の論文
著者
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Zen Shonosuke
School Of Pharmaceutical Sciences Kitasato University
-
Koto Shinkiti
School Of Pharmaceutical Sciences Kitasato University
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Omura Satoshi
The Kitasato Inst.
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Yago Kazuo
School of Pharmaceutical Sciences, Kitasato University
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