Studies on 5-8 fused ring compounds. V. The conformations of eight-membered rings in 5-8-5 fused ring compounds and their cis-trans isomerization.

スポンサーリンク

概要

• 論文の詳細を見る

• The 5-8-5 fused ring compounds, synthesized by photocycloaddition, <I>cis</I>-<I>cisoid</I>-<I>cis</I>- and <I>cis</I>-<I>transoid</I>-<I>cis</I>-tricyclo[9.3.0.0<SUP>4,8</SUP>]tetradecane-2,9-dione (<B>1-A</B> and <B>2-A</B>) and <I>cis</I>-<I>cisoid</I>-<I>cis</I>-tricyclo[9.3.0.0<SUP>3,7</SUP>]tetradecane-2,9-dione (<B>3-A</B>) were isomerized to trans isomers (<B>1-B</B>, <B>1-C</B>, <B>2-B</B>, <B>2-C</B>, and <B>3-B</B>) at ring junction under basic conditions. Their molecular structures except for <B>1-B</B> were determined by X-ray crystallography. The eight-membered rings of these 5-8-5 fused ring compounds were found in various conformations, boat-chair, twist-boat (S<SUB>4</SUB>), chair, twist-boat-chair, and chair-chair forms. With regard to the conformations of their eight-membered rings the strain energies were calculated by MM2 and the predicted conformations were compared with those obtained by X-ray crystallography.

• 公益社団法人 日本化学会の論文

著者

• Zen Shonosuke

  School Of Pharmaceutical Sciences Kitasato University

• Saito Yoshihiko

  Department Of Cardiology Juntendo University School Of Medicine

• OHBA SHIGERU

  Deparment of Biology, Faculty of Science, Tokyo Metropolitan University

• Okuda Masami

  Department of Chemistry, Faculty of Science and Technology, Keio University

• Ito Masatoki

  Department of Chemistry, Faculty of Science and Technology, Keio University

• Umehara Misao

  Department of Chemistry, Keio University

• Hishida Shinzabro

  Naka Works, Hitachi Ltd.

関連論文

• Clinical Importance of Adherence to Treatment With Eicosapentaenoic Acid by Patients With Hypercholesterolemia
• Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan
• 1 Long-Term Feasibility of TACT and Cardiac Regeneration Enhancement by Intra-Coronary Infusion of Peripheral Blood Mononuclear Cells (CARE-PB-AMI) or Erythropoietin (CARE-EPO-AMI)(Clinical Trials of Regeneration Therapy in Japan, The 71st Annual Scientif
• Concentrations of Th1/Th2 Cytokines and C-Reactive Protein in Patients with Coronary Atherosclerosis and Acute Coronary Syndrome
• Circulating Oxidized Low-Density Lipoprotein Is an Independent Predictor for Cardiac Events in Patients with Coronary Artery Disease
• IS040 Positive association between essential hypertension and Glu298Asp polymorphism in the endothelial nitric oxide synthase gene
• Benzyl Derivatives of N-2,4-Dinitrophenyl-D-glucosamine and Their Use for Oligosaccharide Synthesis
• Adipocytokines as new promising markers of colorectal tumors : Adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer
• Subaru Deep Survey I. Near-Infrared Observations
• Relationship between plasma level of cardiotrophin-1 and left ventricular mass index in patients with dilated cardiomyopathy
• Characterization of Dimeric Copper(II) Trichloroacetate Complexes by Electron Spin Resonance, Infrared, and Electronic Reflectance Spectra. Correlation of Spectral Parameters with Molecular Geometry
• OJ-073 Atrial Functional Reserve as a Predictor for Fixed Atrial Fibrillation in Patients with Hypertrophic Cardiomuopathy(Cardiac function, basic/clinical(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation S
• Lack of Association between T^→C Mutation in the 5'-Flanking Region of the Endothelial Nitric Oxide Synthase Gene and Essential Hypertension
• Assisting the Diagnosis of Thyroid Diseases with Bayesian-Type and SOM-Type Neural Networks Making Use of Routine Test Data
• Superwind-Driven Intense H_2 Emission in NGC 6240
• Dual Gradient-echo In-phase and Opposed-phase Magnetic Resonance Imaging to Evaluate Lipomatous Metaplasia in Patients with Old Myocardial Infarction
• Syntheses of Penta-O-benzyl-myo-inositols, O-β-L-Arabinosyl-(1→2)-sn-myo-inositol, O-α-D-Galactosyl-(1→3)-sn-myo-inositol, and O-α-D-Galactosyl-(1→6)-O-α-D-Galactosyl-(1→3)-sn-myo-inositol
• Glycosylation Using 2-Azido-3,4,6-tri-ο-benzyl-2-deoxy-D-glucose,-galactose, and -mannose with the Aid of ρ-Nitrobenzenesulfonyl Chloride-Silver Trifluoromethanesulfonate-Triethylamine System
• Synthesis of Glucose-Containing Linear Oligosaccharides Having α(1→4) and α(1→6) Linkages Using Stereoselective Dehydrative Glycosylation
• FOCAS : The Faint Object Camera and Spectrograph for the Subaru Telescope
• Angiotensin II-Induced Ventricular Hypertrophy and Extracellular Signal-Regulated Kinase Activation Are Suppressed in Mice Overexpressing Brain Natriuretic Peptide in Circulation
• SOCS1/JAB Likely Mediates the Protective Effect of Cardiotrophin-1 Against Lipopolysaccharide-Induced Left Ventricular Dysfunction In Vivo
• JAB/SOCS1 and CIS3/SOCS3 inhibit hypertrophic response to cardiotrophin-1 independent of STAT3 suppression in neonatal rat ventricular myocytes
• Genetic disruption of angiotensin II type 2 (AT2) receptor worsened short-term survival after acute myocardial infarction in mice
• Natriuretic peptides induce NF-κ B activation during myocardial ischemia-reperfusion : possible mechanisms of acute inflammation and coronary endothelial apoptotic cell death
• Characterization of Dimeric (Carboxylato)copper(II) Complexes by Electron Spin Resonance Spectra. Correlation of ESR Parameters with Singlet-Triplet Energy Separations
• Structural and Magnetic Studies of Dimeric Copper(II) 2,2-Diphenylpropanoato and Triphenylacetato Complexes with Oxygen-Donor Ligands. The Cage Geometry of Dimeric α-Phenyl Substituted Copper(II) Carboxylates^
• Important Role of Tetrahydrofuran Ring in Activation of Hydrogen Peroxide in the Presence of Binuclear Iron(III) Complexes with Linear μ-Oxo Bridge
• Relaxation of pBR322 Form I DNA by Copper (II) Complex and Hydrogen Peroxide
• Synthesis and Utility of 2-(Benzoyloxyimino)-2-deoxy-α-D-lyxo-hexopyranosyl Bromide as a Novel α-D-Talosaminide Building Block
• A Practical Synthesis of Mannosaminyl-β(1→4)-glucosyl-α(1→2)-rhamnose, the Trisaccharide Repeating Unit of a Streptococcus pneumoniae Capsular Polysaccharide
• Synthesis of a 2-Acetamido-2-deoxy-β-D-mannuronic Acid-Containing Artificial Glycolipid Corresponding to the Repeating Unit of Teichuronic Acid from Micrococcus luteus
• A Pracitical, Highly Stereoselective Synthesis of the Trisaccharide Repeating Unit of a Streptococcus pneumoniae Polysaccharide
• Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
• Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene
• Expedient Synthesis of an Anomerically Modified Trisaccharide Component of the Capsular Polysaccharide from Streptococcus pneumoniae Type 19F
• Synthetic Study on a 26-Membered Macrolide, Amphidinolide B: Synthesis of the C_1-C_13 Fragment
• Antihypertensive Therapy Reduces Increased Plasma Levels of Adrenomedullin and Brain Natriuretic Peptide Concomitant with Regression of Left Ventricular Hypertrophy in a Patient with Malignant Hypertension
• -1059-INHIBITION OF ANP SECRETION BY CIRCULATING LEVEL OF ENDOTHELIN-1 (ET-1) : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Pacemaker System Malfunction Resulting from External Electrical Cardioversion : A Case Report
• Absolute Configuration of (+)-Aureothin: A Toxic Metabolite Possessing γ-Pyrone Unit
• Sensitive Chemiluminescent Enzyme Immunoassay for Determination of Endothelin-1
• A Novel, Readily Accessible Lactosaminyl Donor : N-Trichloroethoxycarbonyl-hexa-0-benzoyl-β-D-lactosaminyl Fluoride :
• Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers
• Using Imaging Mass Spectrometry to Accurately Diagnose Fabry's Disease
• Generator of Gauge Transformation in Phase Space and Velocity Phase Space : Particles and Fields
• Genetic Polymorphisms of FCGRT Encoding FcRn in a Japanese Population and Their Functional Analysis
• Early Lower Rectal Carcinoma with Synchronous Isolated Lateral Pelvic Lymph Node Metastasis : Report of a Case
• Plasma concentrations of VCAM-1 and PAI-1 : A predictive biomarker for post-operative recurrence in colorectal cancer
• Detection of Aldosterone Synthase Gene Expression in the Failing Human Ventricle : Quantitative Analysis Using a Newly Modified Real-Time RT-PCR
• 3 Sophisticated balance of renin angiotensin system and natriuretic peptide system in normal and infarct hearts(Symposium 1 (SY1) (H) : Cardiovascular Neurohumoral System : Novel Aspect of Angiotensin and Aldosterone Receptor)(Special Program)
• Stereoselective Syntheses of α-Glucuronides Using Dehydrative Glycosylation
• CURRENT STATUS IN THE OCCURRENCE OF POSTOPERATIVE BLEEDING, PERFORATION AND RESIDUAL/LOCAL RECURRENCE DURING COLONOSCOPIC TREATMENT IN JAPAN
• Systemic chemotherapy for peritoneal disseminated gastric cancer with inadequate oral intake : a retrospective study
• PREVALENCE AND CLINICOPATHOLOGICAL FEATURES OF NONPOLYPOID COLORECTAL NEOPLASMS : SHOULD WE PAY MORE ATTENTION TO IDENTIFYING FLAT AND DEPRESSED LESIONS?
• MID-TERM PROGNOSIS AFTER ENDOSCOPIC RESECTION FOR SUBMUCOSAL COLORECTAL CARCINOMA : SUMMARY OF A MULTICENTER QUESTIONNAIRE SURVEY CONDUCTED BY THE COLORECTAL ENDOSCOPIC RESECTION STANDARDIZATION IMPLEMENTATION WORKING GROUP IN JAPANESE SOCIETY FOR CANCER
• Is natriuretic peptide the best way to diagnose congestive heart failure?
• Intensive Lipid-Lowering Therapy With Rosuvastatin Stabilizes Lipid-Rich Coronary Plaques : Evaluation Using Dual-Source Computed Tomography
• Plaque-Stabilizing Statin Therapy Prior to Percutaneous Transluminal Angioplasty and Stenting : Reply
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer
• PJ-165 Myocardial Viability is Different in Systolic and Diastolic Function in Akinetic Region in Acute Myocardial Infarction : a Follow-up Study(Acute myocardial infarction, clinical (diagnosis/treatment)-8, The 71st Annual Scientific Meeting of the Japa
• X-ray structural studies of green and brown crystals of trans-(CoC)2(N48))X(N48=1,4,7,10-tetraazacyclopentadecane, X=NO3-, BF4-, and ClO4-).
• Preventive Effects of Eicosapentaenoic Acid on Coronary Artery Disease in Patients With Peripheral Artery Disease : Subanalysis of the JELIS Trial
• Preparation and characterization of rhodium(III) complexes containing (2-aminoethyl)dimethylphosphine (edmp) or 1,2-bis(dimethylphosphino)ethane (dmpe). Structures of fac-[Rh(edmp)3]3+, trans(Cl,Cl),cis(P,P)-[RhCl2(edmp)2]+, and trans-[RhCl2(dmpe)2]+.
• Green and brown isomers of the ((S)-1-amino-2-propanethiolato-N,S)(1,4,7,10-tetraazacyclododecane)cobalt(III) ion and crystal structure of the green isomer.
• Cobalt(III)-peroxo complexes containing 1,2-bis(dimethylphosphino)ethane (dmpe) or 1,3-bis(dimethylphosphino)propane (dmpp). Molecular structures of (Co(O2)(dmpe)2)B(C6H5)4 and (Co(O2)(dmpp)2)BF4H2O.
• Syntheses of Isomaltose, Isomaltotetraose, and Isomaltooctaose
• A study of the rapid anomerization of poly-O-benzyl-.BETA.-D-glucopyranosides with titanium tetrachloride.
• A stereoselective one-stage .ALPHA.-glucosylation with 2,3,4,6-tetra-O-benzyl-.ALPHA.-D-glucopyranose and a mixture of methanesulfonic acid, cobalt(II) bromide, and tetraethylammonium perchlorate.
• The direct synthesis of methyl 2,4-di-O-benzyl-.ALPHA.-D-xylopyranoside by the regiospecific benzylation of methyl .ALPHA.-D-xylopyranoside.
• Synthesis of O-.BETA.-D-glucopyranosyl-(1.RAR.2)-O-.BETA.-D-glucopyranosyl-(1.RAR.6)-D-glucopyranose; Dehydrative .BETA.-D-glucosylation using 2-O-acetyl-3,4,6-tri-O-benzyl-D-glucopyranose.
• The synthesis of .ALPHA.-D-galactopyranosyl and .ALPHA.-D-mannopyranosyl 2-amino-2-deoxy-.ALPHA.-D-glucopyranosides and the conformation of their glycoside linkage.
• .ALPHA.-D-glucosylation by 6-O-acetyl-2,3,4-tri-O-benzyl-D-glucopyranose using trimethylsilyl triflate and pyridine. Synthesis of .ALPHA.-maltosyl and .ALPHA.-isomaltosyl .ALPHA.-D-glucosides.
• Partial benzylation of methyl .ALPHA.- and .BETA.-D-galactopyranosides.
• Stereoselective synthesis of mixed acetal glycosides by reaction of tri-O-acetyl-N-(2,4-dinitrophenyl)-.ALPHA.-D-glucosaminyl bromide with alcohol in acetone.
• A through-process for the preparation of methyl per-O-acetyl 1-thio-glycosides from aldoses.
• Synthesis of Anomeric Methyl 6-O-(L-Mycarosyl)-β-D-glucosaminides and 4-O-(L-Mycarosyl)-β-D-mycaminosides
• The Synthesis of Methyl 2,4,6-Tri-O-benzyl-α-D-glucopyranoside
• Partially benzylated derivatives of 6-deoxy-D-glucose.
• .ALPHA.-Glucosylation of phenols with tetra-O-benzyl-.ALPHA.-D-glucose.
• The stereoselective dehydrative .ALPHA.-glucosylation using 6-O-acetyl- and 6-O-p-nitrobenzoyl-2,3,4-tri-O-benzyl-D-glucopyranoses.
• Synthesis of 4-Substituted Isoxazole-3,5-dicarboxylic Acids from 2-Substituted-1,3-dinitroglutarates and the Reaction Mechanism therefrom
• Glucosidation of tetra-O-benzyl-.ALPHA.-D-glucose with chlorosilane and silver sulfonate.
• Preparation of 2,3,4,6-tetra-O-benzyl-D-mannose.
• Structure and Polarized Spectra of cis-difluorotetraamminecobalt(III) Perchlorate, cis-(CoF2(NH3)4)ClO4.
• The Synthesis of Purine Nucleosides of L-Mycarose and L-Cladinose
• Structural, magnetic and spectroscopic characterization of novel di-.MU.-carboxylato-bridged binuclear copper(II) complexes with 1,10-phenanthroline.
• Structures of three diastereomers of trans(N-Ph, N-Ph)-2,4-pentanedionatobis(N-phenylethylenediamine)cobalt(III) and of one diastereomer of trans(N-Ph, N-Ph)-oxalatobis(N-phenylethylenediamine)cobalt(III) complex cations.
• The crystal structure of ion-exchanged mordenite.
• Preparation and characterization of cis- and trans-(RhCl2(dmap)2)+ (dmap=1,3-bis(dimethylarsino)propane), and X-ray structure analyses of these complexes and trans-(CoCl2(dmap)2)+.
• Preparation and crystal structure of bis((2-aminoethyl)dimethylphosphine)(1,2-bis(dimethylphosphino)ethane)cobalt(III) tribromide dihydrate, (Co{NH2CH2CH2P(CH3)2}2{(CH3)2PCH2CH2P(CH3)2})Br32H2O.
• Stereoselective .ALPHA.-glucosylation with tetra-O-benzyl-.ALPHA.-D-glucose and a mixture of trimethylsilyl bromide, cobalt(II) bromide, tetrabutylammonium bromide, and a molecular sieve. A synthesis of 3,6-di-O-(.ALPHA.-D-glucopyranosyl)-D-glucose.
• The Synthesis of 3-Amino-3-deoxy-D-allose and Related Substances
• 2-methoxyethyl group for protection of reducing hydroxyl group of aldose.
• Studies on 5-8 fused ring compounds. V. The conformations of eight-membered rings in 5-8-5 fused ring compounds and their cis-trans isomerization.
• Structure of cobalt(III) complexes with (R,R)- and (R,S)-N,N,N',N'-tetrakis(2-aminoethyl)-2,4-pentanediamine and N,N,N',N'-tetrakis(2-aminoethyl)-1,3-propanediamine.
• Crystal structure of (-)4C7D4mer-{N-(2-aminoethyl)-1,3-propanediamine}(diethylenetriamine)cobalt(III) iodide monohydrate, (-)4C7D4mer-(Co(aepn)(dien))I3H2O.
• The glucosylation of several alcohols with tetra-O-benzyl-.ALPHA.-D-glucopyranose and a mixture of p-nitrobenzenesulfonyl chloride, silver trifluoromethanesulfonate, and triethylamine.
• Studies on 5-8 fused ring compounds. IV. The syntheses of 5-8-5 fused ring compounds and the conformations of their eight-membered rings.
• A facile synthesis of anomeric methyl DL-tolyposaminides, methyl DL-forosaminides, and related substances.

もっと見る 閉じる

スポンサーリンク