Studies of Hydroxy Amino Acids. II. The Separation of Diastereoisomers of Hydroxy Amino Acids
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概要
- 論文の詳細を見る
It has been found that <I>erythro</I>-β-hydroxy-DL-norvaline, and <I>erythro</I>-β-hydroxy-DL-norleucine, and <I>threo</I>-β-hydroxy-DL-leucine form scarcely-soluble compounds in water with α-naphthylphosphoric acid, tetrachlorophthalic acid, and chlorendic acid, respectively. On the other hand, the compounds of their diastereoisomers with the reagents were soluble in water. On the basis of these facts, β-hydroxy-DL-norvaline, β-hydroxy-DL-norleucine, and β-hydroxy-DL-leucine were successfully separated into their diastereoisomers. The configurational assignment of α-amino-β-hydroxy acids without a branched side chain on the γ-carbon atom was established by means of NMR spectroscopy.
- 公益社団法人 日本化学会の論文
著者
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Ariyoshi Yasuo
Central Research Laboratories Ajinomoto Co. Inc
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Sato Naotake
Central Research Laboratories, Ajinomoto Co., Inc.
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